Results 81 to 90 of about 9,797,826 (264)

Neural Network-Based Histologic Remission Prediction In Ulcerative Colitis [PDF]

arXiv, 2023
BACKGROUND & AIMS: Histological remission (HR) is advocated and considered as a new therapeutic target in ulcerative colitis (UC). Diagnosis of histologic remission currently relies on biopsy; during this process, patients are at risk for bleeding, infection, and post-biopsy fibrosis.
arxiv  

PPARα-targeted mitochondrial bioenergetics mediate repair of intestinal barriers at the host-microbe intersection during SIV infection. [PDF]

, 2019
Chronic gut inflammatory diseases are associated with disruption of intestinal epithelial barriers and impaired mucosal immunity. HIV-1 (HIV) causes depletion of mucosal CD4+ T cells early in infection and disruption of gut epithelium, resulting in ...
Arredondo, Juan, Cortopassi, Gino, Crakes, Katti R, Dandekar, Satya, Datta, Sandipan, Fenton, Anne, Gaulke, Christopher A, Giulivi, Cecilia, Grishina, Irina, Hirao, Lauren A, Marco, Maria L, Napoli, Eleonora, Sankaran-Walters, Sumathi, Santos Rocha, Clarissa   +13 more
core  

Trans-Anastomotic Drainage Tube Placement After Hand-Sewn Anastomosis in Patients Undergoing Intersphincteric Resection for Low Rectal Cancer: An Alternative Drainage Method

Frontiers in Oncology, 2022
Anastomotic leakage (AL) is a common complication after intersphincteric resection (ISR). It significantly reduces quality of life and causes great distress to patients.
Xinjian Zhong, Xinjian Zhong, Xinjian Zhong, Xinjian Zhong, Xinjian Zhong, Xiaoyu Xie, Xiaoyu Xie, Xiaoyu Xie, Xiaoyu Xie, Xiaoyu Xie, Hang Hu, Hang Hu, Hang Hu, Hang Hu, Hang Hu, Yi Li, Yi Li, Yi Li, Yi Li, Yi Li, Shunhua Tian, Shunhua Tian, Shunhua Tian, Shunhua Tian, Shunhua Tian, Qun Qian, Qun Qian, Qun Qian, Qun Qian, Qun Qian, Congqing Jiang, Congqing Jiang, Congqing Jiang, Congqing Jiang, Congqing Jiang, Xianghai Ren, Xianghai Ren, Xianghai Ren, Xianghai Ren, Xianghai Ren   +39 more
doaj   +1 more source

Unraveling the Link between Periodontitis and Inflammatory Bowel Disease: Challenges and Outlook [PDF]

arXiv, 2023
Periodontitis and Inflammatory Bowel Disease (IBD) are chronic inflammatory conditions, characterized by microbial dysbiosis and hyper-immunoinflammatory responses. Growing evidence suggest an interconnection between periodontitis and IBD, implying a shift from the traditional concept of independent diseases to a complex, reciprocal cycle.
arxiv  

INTESTINAL MICROBIOTA IN DIGESTIVE DISEASES [PDF]

Arquivos de Gastroenterologia, 2017
ABSTRACT BACKGROUND In recent years, especially after the development of sophisticated metagenomic studies, research on the intestinal microbiota has increased, radically transforming our knowledge about the microbiome and its association with health maintenance and disease development in humans.
PASSOS, Maria do Carmo Friche, MORAES-FILHO, Joaquim Prado   +1 more
openaire   +6 more sources

Persistent systemic microbial translocation, inflammation, and intestinal damage during Clostridioides difficile infection [PDF]

, 2020
Background. Clostridioides difficile infection (CDI) might be complicated by the development of nosocomial bloodstream infection (n-BSI). Based on the hypothesis that alteration of the normal gut integrity is present during CDI, we evaluated markers of ...
Aversano, L., Battaglia, R., Bruno, G., Ciardi, M. R., Corazziari, E. S., de Angelis, M., Iera, J., Mascellino, M. T., Mastroianni, C. M., Miele, M. C., Morelli, S., Oliva, A., Venditti, M., Vullo, V.   +13 more
core   +1 more source

Regional tissue oxygen saturation during minimal enteral feeding is associated with the subsequent feeding intolerance in very preterm infants

Scientific Reports
Feeding intolerance (FI) is a common clinical problem in very preterm infants (VPIs) and it increases the risk for adverse outcomes. The value of regional tissue oxygen saturation in predicting FI remains unclear. A total of 57 VPIs were involved in this
Jianyun Chen, Xi Fan, Shanshan He, Zhiying Lin, Zhiwen Su, Fan Wu   +5 more
doaj   +1 more source

JNK Pathway-Associated Phosphatase/DUSP22 Suppresses CD4+ T-Cell Activation and Th1/Th17-Cell Differentiation and Negatively Correlates with Clinical Activity in Inflammatory Bowel Disease

Frontiers in Immunology, 2017
This study aimed to investigate the role of JNK pathway-associated phosphatase (JKAP) in inflammatory bowel disease (IBD). JKAP expression was analyzed in the intestinal mucosa of 81 IBD patients and 25 healthy controls (HCs) by qPCR and immunoblotting ...
Rui Zhou, Rui Zhou, Ying Chang, Ying Chang, Jing Liu, Jing Liu, Min Chen, Min Chen, Hongling Wang, Hongling Wang, Meifang Huang, Meifang Huang, Shi Liu, Shi Liu, Xiaobing Wang, Xiaobing Wang, Qiu Zhao, Qiu Zhao   +17 more
doaj   +1 more source

Diseases of the Large Intestine

Cleveland Clinic Journal of Medicine, 1932
Diseases and abnormalities of the large intestine are far too numerous to be described in one paper; I shall discuss, therefore, only the more common conditions that may be encountered in the routine examination of the gastro-intestinal tract. The normal contour and position of the colon, as well as many of the abnormal positions that it may assume ...
openaire   +3 more sources

Intestinal organoids for modelling intestinal development and disease [PDF]

Philosophical Transactions of the Royal Society B: Biological Sciences, 2018
Gastrointestinal diseases are becoming increasingly prevalent in developed countries. Immortalized cells and animal models have delivered important but limited insight into the mechanisms that initiate and propagate these diseases. Human-specific models of intestinal development and disease are desperately needed that can recapitulate structure and ...
Kathryn L. Fair, Jennifer Colquhoun, Nicholas R.F. Hannan, Nicholas R.F. Hannan   +3 more
openaire   +3 more sources