Results 61 to 70 of about 544,713 (308)

Diseases of the Large Intestine

Cleveland Clinic Journal of Medicine, 1932
Diseases and abnormalities of the large intestine are far too numerous to be described in one paper; I shall discuss, therefore, only the more common conditions that may be encountered in the routine examination of the gastro-intestinal tract. The normal contour and position of the colon, as well as many of the abnormal positions that it may assume ...
openaire   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Effects of hygiene and defecation behavior on helminths and intestinal protozoa infections in Taabo, Côte d'Ivoire [PDF]

, 2013
Effect of community-led total sanitation and hygiene education to reduce the transmission of helminthiases and intestinal protozoa ...
Silué, Kigbafori D., Kouadio, Bernadette A., Eveline Hürlimann, Bassirou Bonfoh, Clarisse Houngbedji, Utzinger, Jürg, Yapi, Richard B., Kouassi Dongo, Kouadio Bernadette A., N’Goran Eliézer K., Utzinger Jürg, Richard B Yapi, Houngbedji Clarisse, Zouzou, Fabien, Dongo Kouassi, Bonfoh Bassirou, N'goran, Eliézer K., Jürg Utzinger, Houngbedji, Clarisse, Giovanna Raso, Ouattara Mamadou, Raso, Giovanna, Hürlimann Eveline, Kouassi, Dongo, Acka-Douabélé, Cinthia A., Bonfoh, Bassirou, Fabien Zouzou, Schmidlin, Thomas, Mamadou Ouattara, Cinthia A Acka-Douabélé, Yapi Richard B., Thomas Schmidlin, Bernadette A Kouadio, Silué Kigbafori D., Acka-Douabélé Cinthia A., Eliézer K N'Goran, Schmidlin Thomas, Ouattara, Mamadou, Hürlimann, Eveline, Kigbafori D Silué, Zouzou Fabien, Raso Giovanna   +41 more
core   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

The aetiology of infectious intestinal disease in the community in Malta [PDF]

, 2010
Routine sources of data provide limited information on aetiological agents causing infectious intestinal disease (IID) in the community. A retrospective, age-stratified, cross-sectional, telephone study at community level was performed whereby identified
Gauci, Charmaine, Ruggieri, Franco-Maria, Mamo, Julian, Cuschieri, Liliana, Barbara, Christopher, Gilles, Herbert, Bartolo, Ilaria di   +6 more
core  

Bowel Sounds Detection Method Based on ResNet-BiLSTM and Attention Mechanism

Zhongguo yiliao qixie zazhi
Bowel sounds can reflect the movement and health status of the gastrointestinal tract. However, the traditional manual auscultation method has subjective deviation and is time-consuming and labor-intensive. In order to better assist doctors in diagnosing
Yali HAO, Xianrong WAN, Congqing JIANG, Xianghai REN, Xiaoming ZHANG, Xiang ZHAI   +5 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Intestinal parasitic infections in HIV-infected patients, Lao People's Democratic Republic [PDF]

, 2014
HIV infection is an emerging problem in Laos. We conducted the first prospective study on intestinal parasites, including opportunistic protozoa, in newly diagnosed HIV infected patients, with or without diarrhea.
Borel, Elisabeth, Saykham Phaxayaseng, Jean-François Etard, Niranh Phoumindr, Rabodonirina, Meja, Etard, Jean-François, Luangkhot, E., Vansilalom, Y., Peter Odermatt, Eric Delaporte, Sourinphoumy, Khamphang, Rabodonirina, M., Sengphilom, B., Phaxayaseng, Saykham, Delaporte, Eric, Luangkhot, Elodie, Khamphang Sourinphoumy, Yathmany Vansilalom, Meja Rabodonirina, Elodie Luangkhot, Phoumindr, Niranh, Borel, E., Bouachanh Sengphilom, Paboriboune, Phimpha, Phaxayaseng, S., Odermatt, P., Odermatt, Peter, Sourinphoumy, K., Sengphilom, Bouachanh, Phoumindr, N., Elisabeth Borel, Jean- François Etard, Paboriboune, P., Vansilalom, Yathmany, Phimpha Paboriboune   +34 more
core   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source