Results 131 to 140 of about 5,424,793 (311)

Microfluidic Engineering of Microgels: A Review of Emerging Technologies, Materials, Fabrication Strategies, and Applications

Advanced Healthcare Materials, EarlyView.
Recent advances in microfluidic technologies for microgel fabrication are critically reviewed, highlighting the capabilities and limitations of major microfluidic platforms and discussing how platform design, material selection, and crosslinking strategies influence microgel architecture and functionality. Current challenges and future opportunities in
Afshin Abrishamkar, Laura Neely, Cynthia Pham, Nada Ibrahim, Alexis Larios‐Cervantes, Ben A. Kertesz, Todd Hoare   +6 more
wiley   +1 more source

In vitro co-culture of Clostridium scindens with primary human colonic epithelium protects the epithelium against Staphylococcus aureus

Frontiers in Bioengineering and Biotechnology
A complex and dynamic network of interactions exists between human gastrointestinal epithelium and intestinal microbiota. Therefore, comprehending intestinal microbe-epithelial cell interactions is critical for the understanding and treatment of ...
Hao Wang, Raehyun Kim, Raehyun Kim, Yuli Wang, Kathleen L. Furtado, Christopher E. Sims, Christopher E. Sims, Rita Tamayo, Nancy L. Allbritton   +8 more
doaj   +1 more source

Modeling Early Metastatic Progression in Breast Cancer Using a Barrier‐Free, Perfusable Spheroid‐on‐a‐Chip Platform

Advanced Healthcare Materials, EarlyView.
Open‐port, barrier‐free microfluidic device for modeling early metastatic progression. A centrally positioned tumor spheroid releases invasive cells that migrate through the surrounding matrix and intravasate into endothelialized lateral channels.
Vira Sharko, Claudia Olaizola‐Rodrigo, Clara Bayona, Teodora Ranđelović, Rosa Monge, Estela Solanas, Sara Oliván, Ignacio Ochoa   +7 more
wiley   +1 more source

Dynamic cellular heterogeneity revealed through a time-resolved single-cell atlas: assessment of porcine intestinal organoids as an in vitro model for deoxynivalenol and zearalenone

Journal of Animal Science and Biotechnology
Background Intestinal epithelial cells are supported by dynamic cellular heterogeneity, which is critical for maintaining intestinal homeostasis.
Tae Hong Kang, Jung Woong Yoon, Seung Joon Lim, Chae Hyun Lee, Yo Han Lee, Suhyeon Yun, Heejun Jung, Hyun Jun Jang, Tae Hyun Kim, Sang In Lee   +9 more
doaj   +1 more source

Investigating the properties of cancer stem cells and epithelial to mesenchymal transition in human prostate cancer [PDF]

, 2012
In recent years, the cancer stem cell hypothesis has emerged as a compelling but controversial model of cancer progression. Contrary to the clonal evolution model, the cancer stem cell hypothesis postulates that, akin to normal tissues, tumours are ...
Dunning-Foreman, NL
core  

Mechanoactive Biomaterials for Cell–Matrix Mechanotransduction

Advanced Materials, EarlyView.
The graphical abstract shows how individual triggers (force, light, or temperature) and combined optothermal or receptor‐targeted actuation induce material responses at the tissue, cellular, and receptor scales. Their spatial (global or focused) and temporal (continuous or cyclic) modulation determines the resulting mechanical output.
Yi‐Tung Lu, Alison E. John, Marc A. Fernández‐Yagüe   +2 more
wiley   +1 more source

Numb mitigates intestinal epithelial cell senescence induced by radiation through a PLK1-dependent pathway

Scientific Reports
Radiation-induced senescence of intestinal epithelial cells plays a crucial role in damaging the intestinal mucosal barrier. Previous studies have implicated Numb in regulating intestinal mucosal barrier homeostasis, while Polo-like kinase 1 (Plk1 ...
Yongtao Yang, Xiao Hu, Yuwei Pan, Wen Ji, Tao Liu, Xi Zheng   +5 more
doaj   +1 more source

“Activation‐Resistance Elimination” Regulation by Lanthanide/Transition Metal Ion‐Coordinated Nanostructures Intensifies Cuproptosis and Tumor Immunotherapy

Advanced Materials, EarlyView.
The lanthanide/transition metal ion coordination nanoparticles, La‐Cu@Lap/IWR‐1, with optimized coordination, have been proven to achieve remarkable results in realizing comprehensive tumor cuproptosis through efficient cuproptosis activation and multidimensional resistance elimination, thereby synchronously realizing the synergistic antitumor effects ...
Junrong Wang, Mengqian Xu, Huaping Zhao, Yulin Xie, Guoqing Zhu, Haoze Li, Qianqian Sun, Yong Lei, Chunxia Li   +8 more
wiley   +1 more source

Cellular Plasticity in Gut and Liver Regeneration

Gut and Liver
The intestine and liver share a unique regenerative property that sets them apart from other mammalian visceral organs. The intestinal epithelium exhibits rapid renewal, making it one of the fastest renewing tissues in humans.
Minwook Kim, Yoojeong Park, You Sun Kim, Sungjin Ko   +3 more
doaj   +1 more source

Hyperinvasiveness in the major food-borne pathogen Campylobacter jejuni [PDF]

, 2009
Campylobacter jejuni is a common cause of human gastrointestinal infections. Invasion of host epithelial cells is believed to be an important virulence Mechanism of this bacterium. C.
Javed, Muhammad Afzal, Javed, MA
core