Results 1 to 10 of about 669,928 (206)
Intestinal subepithelial myofibroblasts support in vitro and in vivo growth of human small intestinal epithelium. [PDF]
PLoS ONE, 2011 The intestinal crypt-niche interaction is thought to be essential to the function, maintenance, and proliferation of progenitor stem cells found at the bases of intestinal crypts.
Nicholas Lahar +9 more
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Spatial transcriptome analysis of myenteric plexus and intestinal epithelium of colon in patients with Parkinson’s disease [PDF]
Acta Neuropathologica CommunicationsAlpha-synuclein (AS) accumulation is found in the nerve plexuses of the gastrointestinal tract in patients with Parknison’s disease (PD). Moreover, alterations in microbiome composition and its metabolites were confirmed in the colon of patients with PD.
Chaewon Shin +8 more
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Tuft cells: sentinels of the intestinal mucosa
Comptes Rendus Biologies, 2021 The intestinal epithelium is one of our main interfaces with the outside world, including the intestinal microbiota. This epithelium thus combines the two essential functions of nutrient absorption and barrier.
Jay, Philippe
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Frontiers in Cell and Developmental Biology, 2021 This study aimed to determine whether Bmi-1 deficiency leads to intestinal epithelial barrier destruction and microbiota dysfunction, which members of the microbial community alter barrier function with age, and whether p16INK4a deletion could reverse ...
Jiawen Zhou +14 more
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Intestinal cellular heterogeneity and disease development revealed by single-cell technology
Cell Regeneration, 2022 The intestinal epithelium is responsible for food digestion and nutrient absorption and plays a critical role in hormone secretion, microorganism defense, and immune response.
Yalong Wang +4 more
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Effects of six common dietary nutrients on murine intestinal organoid growth. [PDF]
PLoS ONE, 2018 The intestinal epithelium of the gastrointestinal (GI) tract constantly renews itself to absorb nutrients and provide protection for the body from the outside world.
Tenson Cai +5 more
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iScience, 2021 Summary: Homeostasis in the intestinal epithelium is maintained by Lgr5-positive intestinal stem cells (ISCs) located at the base of the crypt. The function of ISCs is reduced upon aging which leads to a decline of regeneration of the intestinal ...
Kodandaramireddy Nalapareddy +4 more
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iScience, 2023 Summary: Upon exposure to a bacterial pore-forming toxin, enterocytes rapidly purge their apical cytoplasm into the gut lumen, resulting in a thin intestinal epithelium.
Catherine Socha +6 more
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Intestinal fatty acid binding protein regulates mitochondrion β-oxidation and cholesterol uptake
Journal of Lipid Research, 2008 The role of intestinal fatty acid binding protein (I-FABP) in lipid metabolism remains elusive. To address this issue, normal human intestinal epithelial cells (HIEC-6) were transfected with cDNA to overexpress I-FABP and compared with cells treated with
Alain Montoudis +10 more
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Cellular and Molecular Gastroenterology and Hepatology, 2021 The healthy gut is achieved and maintained through a balanced relationship between the mucosal immune system, microbial communities resident in the lumen, and the intestinal epithelium.
Huong D. Nguyen +2 more
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