Results 31 to 40 of about 669,928 (206)

The RNA Polymerase III Subunit Polr3b Is Required for the Maintenance of Small Intestinal Crypts in MiceSummary

Cellular and Molecular Gastroenterology and Hepatology, 2016
Background & Aims: The continuously self-renewing mammalian intestinal epithelium, with high cellular turnover, depends on adequate protein synthesis for its proliferative capacity.
Julia E. Kieckhaefer, Sabina Lukovac, Diana Z. Ye, Dolim Lee, Danielle J. Beetler, Michael Pack, Klaus H. Kaestner   +6 more
doaj   +1 more source

Intestinal barrier function and absorption in pigs after waeaning: a review [PDF]

, 2011
Under commercial conditions, weaning of piglets is associated with social, environmental and dietary stress. Consequently, small-intestinal barrier and absorptive functions deteriorate within a short time after weaning.
Wijtten, P.J.A., Verstegen, M.W.A., Meulen, J., van der   +2 more
core   +1 more source

Advances in intestinal epithelium and gut microbiota interaction [PDF]

Frontiers in Microbiology
Hanmin Liu
exaly   +2 more sources

The ‘de novo’ DNA methyltransferase Dnmt3b compensates the Dnmt1-deficient intestinal epithelium

eLife, 2016
Dnmt1 is critical for immediate postnatal intestinal development, but is not required for the survival of the adult intestinal epithelium, the only rapidly dividing somatic tissue for which this has been shown.
Ellen N Elliott, Karyn L Sheaffer, Klaus H Kaestner   +2 more
doaj   +1 more source

STIM1 Deficiency In Intestinal Epithelium Attenuates Colonic Inflammation and Tumorigenesis by Reducing ER Stress of Goblet CellsSummary

Cellular and Molecular Gastroenterology and Hepatology, 2022
Background & Aims: As an indispensable component of store-operated Ca2+ entry, stromal interaction molecule 1 (STIM1) is known to promote colorectal cancer and T-cell–mediated inflammatory diseases.
Xiaojing Liang, Jiansheng Xie, Hao Liu, Rongjie Zhao, Wei Zhang, Haidong Wang, Hongming Pan, Yubin Zhou, Weidong Han   +8 more
doaj   +1 more source

Development and differentiation of the intestinal epithelium

Cellular and Molecular Life Sciences (CMLS), 2003
The gastrointestinal tract develops from a simple tube to a complex organ with patterns of differentiation along four axes of asymmetry. The organ is composed of all three germ layers signaling to each other during development to form the adult structure.
de Santa Barbara, Pascal, van den Brink, Gijs, Roberts, Drucilla   +2 more
openaire   +3 more sources

Developing a 3D intestinal epithelium model for livestock species [PDF]

, 2019
The in vitro 3D culture of intestinal epithelium is a valuable resource in the study of its function. Organoid culture exploits stem cells’ ability to regenerate and produce differentiated epithelium.
Wastling, JM, Fong, WY, Hartley, CS, Campbell, BJ, Armstrong, SD, Coombes, JL, Luu, L, Johnston, LJ, Randle, N, Duckworth, CA, Derricott, H   +10 more
core   +3 more sources

Neutrophil–Epithelial Crosstalk During Intestinal InflammationSummary

Cellular and Molecular Gastroenterology and Hepatology, 2022
Neutrophils are the most abundant leukocyte population in the human circulatory system and are rapidly recruited to sites of inflammation. Neutrophils play a multifaceted role in intestinal inflammation, as they contribute to the elimination of invading ...
Le Kang, Xue Fang, Yi-Hang Song, Zi-Xuan He, Zhi-Jie Wang, Shu-Ling Wang, Zhao-Shen Li, Yu Bai   +7 more
doaj   +1 more source

Organoids and Their Use in Modeling Gut Epithelial Cell Lineage Differentiation and Barrier Properties During Intestinal Diseases

Frontiers in Cell and Developmental Biology, 2021
Maintenance of intestinal epithelium homeostasis is a complex process because of the multicellular and molecular composition of the gastrointestinal wall and the involvement of surrounding interactive signals.
Dianne Pupo Gómez, Francois Boudreau
doaj   +1 more source

Glycosylation in Intestinal Epithelium

, 1991
This chapter reviews the glycosylation reactions in the intestinal epithelium. The intestinal epithelium represents a good model system in which the glycosylation process can be studied. The intestinal epithelium is composed of two basic epithelial cell types: the absorptive enterocyte and the mucus-producing goblet cell.
Taatjes DJ, Roth J
openaire   +4 more sources