Results 51 to 60 of about 669,928 (206)

Epithelial NAD+ depletion drives mitochondrial dysfunction and contributes to intestinal inflammation

open access: yesFrontiers in Immunology, 2023
IntroductionWe have previously demonstrated that a pathologic downregulation of peroxisome proliferator-activated receptor–gamma coactivator 1-alpha (PGC1α) within the intestinal epithelium contributes to the pathogenesis of inflammatory bowel disease ...
Elizabeth A. Novak   +20 more
doaj   +1 more source

Crystals in the Intestinal Epithelium of Neonatal Pigs [PDF]

open access: yesPathologia veterinaria, 1969
Laminated crystalline structures occurred within vacuoles of absorptive intestinal cells in colostrum-fed pigs. They are believed to be bilirubin crystals formed by breakdown of ingested red blood cells, but this could not be substantiated histochemically, and they could not be produced experimentally.
T E, Staley, E W, Jones, L D, Corley
openaire   +2 more sources

Inflammasomes in the Intestinal Epithelium [PDF]

open access: yes, 2023
Inflammasomes are multiprotein signalling complexes that detect a diverse range of pathological stimuli to activate inflammatory caspases, resulting in cell death and the release of IL-18 and IL-1. Inflammasomes are important in a wide range of diseases,
Bruce, Jessica
core  

The intestine: A highly dynamic microenvironment for IgA plasma cells

open access: yesFrontiers in Immunology, 2023
To achieve longevity, IgA plasma cells require a sophisticated anatomical microenvironment that provides cytokines, cell-cell contacts, and nutrients as well as metabolites.
Katharina Pracht   +4 more
doaj   +1 more source

Localization of Endotoxin in the Rat Intestinal Epithelium [PDF]

open access: yesThe Journal of Infectious Diseases, 2000
High levels of circulating lipopolysaccharide (LPS) cause intestinal inflammation and increased permeability to bacteria and toxins. To better understand the effects of LPS on the gut, confocal microscopy and immunofluorescence staining were used to examine the distribution of LPS in the rat intestine after intravenous or enteral administration.
Y, Ge, R M, Ezzell, H S, Warren
openaire   +2 more sources

The Intestinal Epithelium – Fluid Fate and Rigid Structure From Crypt Bottom to Villus Tip

open access: yesFrontiers in Cell and Developmental Biology, 2021
The single-layered, simple epithelium of the gastro-intestinal tract controls nutrient uptake, coordinates our metabolism and shields us from pathogens.
Vangelis Bonis   +2 more
doaj   +1 more source

Cdx2 regulates patterning of the intestinal epithelium

open access: yesDevelopmental Biology, 2010
Cdx1, Cdx2 and Cdx4 encode homeodomain transcription factors that are involved in vertebral anterior-posterior (AP) patterning. Cdx1 and Cdx2 are also expressed in the intestinal epithelium during development, suggesting a role in this tissue. Intestinal defects have not been reported in Cdx1 null mutants, while Cdx2 null mutants die at embryonic day 3.
Grainger, Stephanie   +2 more
openaire   +2 more sources

Regulation of Gene Expression in the Intestinal Epithelium [PDF]

open access: yes, 2010
Regulation of gene expression within the intestinal epithelium is complex and controlled by various signaling pathways that regulate the balance between proliferation and differentiation. Proliferation is required both to grow and to replace cells lost through apoptosis and attrition, yet in all but a few cells, differentiation must take place to ...
Camilla A, Richmond, David T, Breault
openaire   +2 more sources

Prevalência de metaplasia intestinal na junção esofagogástrica no Instituto de Endiscopia do Planalto [PDF]

open access: yes, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Ciências Médicas, Florianópolis, 2006.Os estudos de prevalência de metaplasia intestinal na junção esofagogástrica são recentes na ...
Guzatti Fiho, Osmar
core  

Human intestinal spirochetes are distinct from Serpulina hyodysenteriae [PDF]

open access: yes, 1993
Twenty-nine intestinal spirochetes isolated from Australian aboriginal children and six strains from Italian adults (HRM1, -2, -4, -5, -7, and -14) were genetically examined at 15 enzyme loci by using multilocus enzyme electrophoresis.
Lymbery, A.J.   +3 more
core  

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