Results 1 to 10 of about 5,424,793 (311)
Emerging Microbes and Infections, 2023 Intestinal epithelial cell interactions with enteric pathogens have been incompletely elucidated owing to the lack of model systems that recapitulate the cellular diversity, architecture and functionality of the intestine.
Miaomiao Yan +8 more
doaj +1 more source
Intestinal epithelial cells necroptosis and its association with intestinal inflammation [PDF]
Ķazaķstannyṇ Klinikalyķ Medicinasy, 2019 This review focuses on the role of necroptosis, an alternative mode of cell death, in the pathogenesis of diseases associated with intestinal inflammation whose prevalence has been significantly increased for last decades, which substantiates the ...
Anton S. Tkachenko
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 Intestinal epithelial cells are critical for nutrient absorption and defending against pathogen infection. Deoxynivalenol (Don), the most common mycotoxin, contaminates cereals and food throughout the world, causes serious damage to mammal intestinal ...
Lianjie Hou +5 more
doaj +1 more source
Cellular and Molecular Gastroenterology and Hepatology, 2021 Background & Aims: Inflammatory bowel disease is commonly treated by administration of glucocorticoids. While the importance of intestinal epithelial cells for the pathogenesis of this disorder is widely accepted, their role as target cells for ...
Chiara Muzzi +6 more
doaj +1 more source
Alpha-Lipoic Acid Promotes Intestinal Epithelial Injury Repair by Regulating MAPK Signaling Pathways
Mediators of Inflammation, 2022 Intestinal epithelial cells are an essential barrier in human gastrointestinal tract, and healing of epithelial wound is a key process in many intestinal diseases.
Yu Yang +6 more
doaj +1 more source
Activation of intestinal epithelial Stat3 orchestrates tissue defense during gastrointestinal infection. [PDF]
PLoS ONE, 2015 Gastrointestinal infections with EHEC and EPEC are responsible for outbreaks of diarrheal diseases and represent a global health problem. Innate first-line-defense mechanisms such as production of mucus and antimicrobial peptides by intestinal epithelial
Nadine Wittkopf +8 more
doaj +1 more source
Intestinal epithelial BLT1 promotes mucosal repair
JCI Insight, 2022 Acute and chronic intestinal inflammation is associated with epithelial damage, resulting in mucosal wounds in the forms of erosions and ulcers in the intestinal tract.
Shusaku Hayashi +7 more
doaj +1 more source
Microorganisms, 2021 Cryptosporidium is a genus of protozoan parasites that infect the gastrointestinal epithelium of a variety of vertebrate hosts. Intestinal epithelial cells are the first line of defense and play a critical role in orchestrating host immunity against ...
Wei He +9 more
doaj +1 more source
Cholera Toxin Suppresses Expression of Ubiquitin Editing Enzyme A20 and Enhances Transcytosis
Cellular Physiology and Biochemistry, 2013 Background: The ubiquitin editing enzyme A20 plays an important role in maintaining the homeostasis in the body Microbe-derived adjuvants are commonly used in animal models of intestinal allergy.
Ming-Yang Li +3 more
doaj +1 more source
Modeling gut neuro-epithelial connections in a novel microfluidic device
Microsystems & Nanoengineering, 2023 The intestinal lumen is filled with diverse chemical and physical stimuli. Intestinal epithelial cells sense these stimuli and signal to enteric neurons which coordinate a range of physiologic processes required for normal digestive tract function.
Jose M. de Hoyos-Vega +11 more
doaj +1 more source