Results 11 to 20 of about 5,424,793 (311)

Regulation of intestinal epithelial homeostasis by mesenchymal cells

Inflammation and Regeneration
The gastrointestinal tract harbors diverse microorganisms in the lumen. Epithelial cells segregate the luminal microorganisms from immune cells in the lamina propria by constructing chemical and physical barriers through the production of various factors
Hisako Kayama, Kiyoshi Takeda
doaj   +3 more sources

Intestinal Epithelial Cells In Vitro [PDF]

Stem Cells and Development, 2010
Recent advances in the biology of stem cells has resulted in significant interest in the development of normal epithelial cell lines from the intestinal mucosa, both to exploit the therapeutic potential of stem cells in tissue regeneration and to develop treatment models of degenerative disorders of the digestive tract.
Dharam P, Chopra, Alan A, Dombkowski, Paul M, Stemmer, Graham C, Parker   +3 more
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"Tolerosomes" are produced by intestinal epithelial cells [PDF]

European Journal of Immunology, 2001
The development of immunological tolerance to orally fed antigens depends on the sampling, processing and transportation events followed in the intestinal epithelium. We present here a description of a "tolerosome": a supra-molecular, exosome-like structure assembled in and released from the small intestinal epithelial cell.
M, Karlsson, S, Lundin, U, Dahlgren, H, Kahu, I, Pettersson, E, Telemo   +5 more
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Epigenetics in Intestinal Epithelial Cell Renewal [PDF]

Journal of Cellular Physiology, 2016
A controlled balance between cell proliferation and differentiation is essential to maintain normal intestinal tissue renewal and physiology. Such regulation is powered by several intracellular pathways that are translated into the establishment of specific transcription programs, which influence intestinal cell fate along the crypt-villus axis.
Roostaee, Alireza, Benoit, Yannick D., Boudjadi, Salah, Beaulieu, Jean‐François   +3 more
openaire   +2 more sources

A key role for E-cadherin in intestinal homeostasis and Paneth cell maturation. [PDF]

, 2010
E-cadherin is a major component of adherens junctions. Impaired expression of E-cadherin in the small intestine and colon has been linked to a disturbed intestinal homeostasis and barrier function.
Trülzsch, Konrad, Eckhard Wolf, Sylvia Steininger, Hirschi Benjamin, Müller-Höcker Josef, Frank T Kolligs, Allgäuer, Michael, Marlon R. Schneider, Schneider Marlon R., Dahlhoff, Maik, Gerhard Markus, Schneider, Marlon R., Konrad Trülzsch, Vogelmann, Roger, Maik Dahlhoff, Müller-Höcker, Josef, Michael Allgäuer, Allgäuer Michael, Horst David, Roger Vogelmann, Markus Gerhard, Horst, David, Frank T. Kolligs, Wolf Eckhard, Dahlhoff Maik, Benjamin Hirschi, Kolligs, Frank T., David Horst, Trülzsch Konrad, Wolf, Eckhard, Josef Müller-Höcker, Kolligs Frank T., Marlon R Schneider, Hirschi, Benjamin, Steininger Sylvia, Gerhard, Markus, Steininger, Sylvia, Vogelmann Roger, Schneider, MR;Dahlhoff, M;Horst, D;Hirschi, B;Trülzsch, K;Müller-Höcker, J;Vogelmann, R;Allgauer, M;Gerhard, M;Steininger, S;Wolf, E;Kolligs, FT   +38 more
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Interactions of intestinal epithelial cells with bacterial extracellular products [PDF]

The enteric microflora represents one of the densest microbial populations in the biological world; as a consequence, the intestinal immune system is constantly exposed to high concentrations of antigenic materials. One of the major frontline defences in
Patten, Daniel
core   +3 more sources

Selective non-steroidal glucocorticoid receptor agonists attenuate inflammation but do not impair intestinal epithelial cell restitution in vitro [PDF]

, 2012
Introduction: Despite the excellent anti-inflammatory and immunosuppressive action of glucocorticoids (GCs), their use for the treatment of inflammatory bowel disease (IBD) still carries significant risks in terms of frequently occurring severe side ...
Kerstin C Reuter, Jürgen Stein, Axel U Dignass, Stefan M Loitsch, Dieter Steinhilber (182458), Reuter, Kerstin C., Dignaß, Axel Uwe, Kerstin C. Reuter (186426), Dieter Steinhilber, Stefan M. Loitsch (186433), Loitsch, Stefan Marcel, Stein, Jürgen, Axel U. Dignass (186440), Steinhilber, Dieter, Jürgen Stein (186447)   +14 more
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(Na+ + K+)-ATPase and plasma membrane polarity of intestinal epithelial cells : presence of a brush border antigen in the distal large intestine that is immunologically related to beta subunit [PDF]

, 1989
The previously produced monoclonal antibody IEC 1/48 against cultured rat intestinal crypt cells (Quaroni, A., and K. J. Isselbacher. 1981. J. Natl. Cancer Inst.
Quaroni, A., B Stieger, Kashgarian, M., Marxer, A., A Marxer, A Quaroni, M Kashgarian, Stieger, B., Hauri, H. P., H P Hauri, Marxer A, Stieger B, Kashgarian M, Quaroni A, Hauri HP   +14 more
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Epithelial organization and cyst lumen expansion require efficient Sec13-Sec31-driven secretion [PDF]

, 2012
Epithelial morphogenesis is directed by interactions with the underlying extracellular matrix. Secretion of collagen and other matrix components requires efficient coat complex II (COPII) vesicle formation at the endoplasmic reticulum. Here, we show that
Schmidt, Katy, Hodgson, Lorna, Stephens, David J, Townley, Anna K   +3 more
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Nocodazole, a microtubule-active drug, interferes with apical protein delivery in cultured intestinal epithelial cells (Caco-2) [PDF]

, 1989
The polarized delivery of membrane proteins to the cell surface and the initial secretion of lysosomal proteins into the culture medium were studied in the polarized human intestinal adenocarcinoma cell line Caco-2 in the presence or absence of the ...
Hauri, H.P., Klumperman, J., Eilers, U., U Eilers, J Klumperman, Hauri, H. P., H P Hauri, Klumperman J, Hauri HP, Eilers U   +9 more
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