Results 61 to 70 of about 669,928 (206)
BMP suppresses Wnt signaling via the Bcl11b-regulated NuRD complex to maintain intestinal stem cells
The EMBO JournalLgr5+ intestinal stem cells (ISCs) are crucial for the intestinal epithelium renewal and regeneration after injury. However, the mechanism underlying the interplay between Wnt and BMP signaling in this process is not fully understood. Here we report that
Yehua Li +12 more
doaj +1 more source
Intestinal stem cells: guardians of homeostasis in health and aging amid environmental challenges
Experimental and Molecular MedicineThe intestinal epithelium is the first line of defense and acts as an interface between the vast microbial world within the gastrointestinal tract and the body’s internal milieu. The intestinal epithelium not only facilitates nutrient absorption but also
Jiahn Choi, Leonard H. Augenlicht
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Intermediate Filaments and Polarization in the Intestinal Epithelium [PDF]
Cells, 2016 The cytoplasmic intermediate filament cytoskeleton provides a tissue-specific three-dimensional scaffolding with unique context-dependent organizational features. This is particularly apparent in the intestinal epithelium, in which the intermediate filament network is localized below the apical terminal web region and is anchored to the apical junction
Richard Coch, Rudolf Leube
openaire +4 more sources
, 2010 The intestinal epithelium is constantly exposed to inducers of reactive oxygen species (ROS), such as commensal microorganisms. Levels of ROS are normally maintained at nontoxic levels, but dysregulation of ROS is involved in intestinal inflammatory ...
Kunihiro Matsumoto +5 more
core +1 more source
, 2016 (A) Intestinal epithelium of Balb-C mouse with normal appearance. (B) Intestinal epithelium showing severe damage with necrotic enteritis. We can observe the loss of microvilli (■), presence of inflammatory cells (ic) and cellular lysis (*) is observed. (
Jorge Reyes-Esparza (3183498) +21 more
core +1 more source
Intrinsic Defense Mechanisms of the Intestinal Epithelium [PDF]
Cell Host & Microbe, 2016 The intestinal epithelium is a single cell layer that facilitates the absorption of nutrients but also provides a tight barrier to prevent pathogen invasion and dissemination of commensal microbes. Specialized epithelial cells of the gastrointestinal tract achieve this frontline defense by working in concert with lymphoid, myeloid, and stromal cells to
Deepshika, Ramanan, Ken, Cadwell
openaire +2 more sources
Mechanism of uric acid transport in intestinal epithelium [PDF]
, 2020 Uric acid is main metabolite from purine degradation pathway in humans a higher primates. Serum uric acid level is controlled on one side by absorbtion and on the other side by excretion. This proceses run in kidney nephrone and in intestinal epithelium.
Vrzáčková, Aneta
core
IL-22 mediates goblet cell hyperplasia and worm expulsion in intestinal helminth infection. [PDF]
, 2013 Type 2 immune responses are essential in protection against intestinal helminth infections. In this study we show that IL-22, a cytokine important in defence against bacterial infections in the intestinal tract, is also a critical mediator of anti ...
Stockinger, Brigitta +8 more
core +1 more source
, 2013 Select list of differentially expressed genes in the Intestinal Epithelium at 21 days post SIV infection.
Xavier Alvarez (33185) +5 more
core +1 more source
Cell Reports, 2013 Immortal spheroids were generated from fetal mouse intestine using the culture system initially developed to culture organoids from adult intestinal epithelium.
Roxana C. Mustata +9 more
doaj +1 more source