Results 111 to 120 of about 5,424,793 (311)
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
LTβR-RelB signaling in intestinal epithelial cells protects from chemotherapy-induced mucosal damage
Frontiers in ImmunologyThe intricate immune mechanisms governing mucosal healing following intestinal damage induced by cytotoxic drugs remain poorly understood. The goal of this study was to investigate the role of lymphotoxin beta receptor (LTβR) signaling in chemotherapy ...
Qiangxing Chen +10 more
doaj +1 more source
Analyses of binding of ITF to intestinal epithelial cells and to epidermal cells.
, 2013 Analyses of binding of ITF to intestinal epithelial cells and to epidermal cells.
Wang Lin (462145) +7 more
core +1 more source
Transcriptional regulation and impact of ABC-transporters in intestinal cell lines [PDF]
, 2009 The intestine has an important role in facilitating and limiting absorption of drugs. Since the intestine forms a barrier to the external, epithelial cells have several properties to protect the body from microorganisms and toxins, and to control uptake ...
Maier, Angelika Erika
core +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
, 2018 In vitro models of the human intestinal epithelium derived from primary stem cells are much needed for the study of intestinal immunology in health and disease. Here, we describe an intestinal monolayer cultured on a porous membrane with accessible basal
Yuli Wang (103182) +11 more
core +1 more source
Effect of green tea extract on expression of proteins involved in drug transport and metabolism and on the expression and secretion of the chemokine interleukin-8 in intestinal cell lines [PDF]
, 2006 Pharmacokinetic interactions often occur as a result of changes in the functional expression of drug-metabolising and transporting proteins. In recent years, interactions of herbal medicines with synthetic drugs have come into focus and drug-interactions
Netsch, Marco Ivo
core +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Molecular Medicine, 2017 Sirtuin-6 (Sirt6) is a critical epigenetic regulator, but its function in the gut is unknown. Here, we studied the role of intestinal epithelial Sirt6 in colitis-associated intestinal epithelial injury.
Fangyi Liu +10 more
doaj +1 more source
Helicobacter pylori-induced histone modification, associated gene expression in gastric epithelial cells, and its implication in pathogenesis. [PDF]
, 2010 Histone modifications are critical in regulating gene expression, cell cycle, cell proliferation, and development. Relatively few studies have investigated whether Helicobacter pylori, the major cause of human gastric diseases, affects histone ...
Haas, Rainer +37 more
core +1 more source