Results 91 to 100 of about 669,928 (206)

Isolation of Serpulina pilosicoli from rectal biopsy specimens showing evidence of intestinal spirochetosis [PDF]

, 1998
Histologic evidence of intestinal spirochetosis (IS) was found in 22 of 41 (53.7%) rectal biopsy specimens from homosexual men attending a sexually transmitted diseases clinic. Serpulina pilosicoli was cultured from 11 of the IS-positive biopsy specimens
Gilbert, G.L., Trivett-Moore, N.L., Hampson, D.J., Law, C.L.H., Trott, D.J.   +4 more
core  

Crosstalk between B lymphocytes, microbiota and the intestinal epithelium governs immunity versus metabolism in the gut

, 2011
Using a systems biology approach, we discovered and dissected a three-way interaction between the immune system, the intestinal epithelium and the microbiota. We found that, in the absence of B cells, or of IgA, and in the presence of the microbiota, the
Matzinger, Polly, William Hsiao, Natalia Shulzhenko, Claire Fraser-Liggett, Oksana Gavrilova, Michele Battle, Andrew J Macpherson, Polly Matzinger, Macpherson, Andrew J, Andrey Morgun, Hsiao, William, Morgun, Andrey, Mayer, Lloyd, Battle, Michele, Yao, Michael, Shulzhenko, Natalia, Marlene Orandle, Michael Yao, Lloyd Mayer, Orandle, Marlene, McCoy, Kathy D, Gavrilova, Oksana, Fraser-Liggett, Claire, Kathy D McCoy, Macpherson, Andrew   +24 more
core   +1 more source

Probiotic-induced changes in the intestinal epithelium: Implications in gastrointestinal disease

, 2009
There is resurgent interest in the use of probiotics to maintain gastrointestinal and systemic health, driven by recent advances in knowledge of bacterial interactions with the epithelium and innate immune system of the intestine.
Ramakrishna, B. S.
core   +1 more source

PRMT5 Maintains Homeostasis of the Intestinal Epithelium by Modulating Cell Proliferation and Survival

Advanced Science
Intestinal homeostasis is sustained by self‐renewal of intestinal stem cells, which continuously divide and produce proliferative transit‐amplifying (TA) and progenitor cells.
Leilei Li, Zhe Zhang, Xu Wang, Haiyong Zhao, Liansheng Liu, Yanhui Xiao, Shan Hua, Ye‐Guang Chen   +7 more
doaj   +1 more source

When Insult Is Added to Injury: Cross Talk between ILCs and Intestinal Epithelium in IBD

Mediators of Inflammation, 2016
Inflammatory bowel disease (IBD) is characterized by an impairment of the integrity of the mucosal epithelial barrier, which causes exacerbated inflammation of the intestine.
Esmé van der Gracht, Sonja Zahner, Mitchell Kronenberg   +2 more
doaj   +1 more source

Investigating signal integration in the intestinal epithelium [PDF]

, 2020
Multicellular tissues arise from a complex collaboration between the constituent cell types. Proper coordination between cells through signal interactions is crucial for tissue renewal and response to environmental changes such as injury or infection ...
Chen, Ina Weilin
core  

Epidermal growth factor reduces autophagy in intestinal epithelium and in the rat model of necrotizing enterocolitis

, 2010
Necrotizing enterocolitis (NEC) is a devastating intestinal disease of premature infants. Epidermal growth factor (EGF) is one of the most promising candidates in NEC prophylaxis.
Kelly M. Arganbright, Melissa D. Halpern, Katerina Dvorak, Andrew A. Maynard, Ashish R. Kurundkar, Akhil Maheshwari, Ludmila Khailova, Bohuslav Dvorak, Holly Dobrenen   +8 more
core   +1 more source

Cell dynamics in fetal intestinal epithelium: implications for intestinal growth and morphogenesis

, 2011
The cellular mechanisms that drive growth and remodeling of the early intestinal epithelium are poorly understood. Current dogma suggests that the murine fetal intestinal epithelium is stratified, that villi are formed by an epithelial remodeling process
Kara L. Hamilton, Lauren B. Curley, Jeffrey D. Hildebrand, Ben Margolis, Mark F. Pressprich, Deborah L. Gumucio, Ann S. Grosse   +6 more
core   +1 more source

Circular RNA Cdr1as inhibits proliferation and delays injury-induced regeneration of the intestinal epithelium

JCI Insight
Circular RNAs (circRNAs) are highly expressed in the mammalian intestinal epithelium, but their functions remain largely unknown. Here, we identified the circRNA Cdr1as as a repressor of intestinal epithelial regeneration and defense.
Hee Kyoung Chung, Lan Xiao, Naomi Han, Jason Chen, Vivian Yao, Cassandra M. Cairns, Benjamin Raufman, Jaladanki N. Rao, Douglas J. Turner, Rosemary Kozar, Myriam Gorospe, Jian-Ying Wang   +11 more
doaj   +1 more source

HPSC-derived organoids express intestinal marker genes at levels comparable to human intestinal epithelium.

, 2015
Results represent day 33 organoids (d42 from hPSC) derived from day 9 CHIR cells. A. Gene expression of intestinal differentiation markers CDX2, KRT20, KLF5, IFABP2 and HOXA13. B. Expression of crypt area/intestinal stem cell markers LGR5, ASCL2 and SOX9.
Diego Balboa (714689), Sanna Toivonen (465679), Zoltan Wiener (5664631), Kari Alitalo (42940), Timo Otonkoski (250629), Kaisa Tamminen (778132), Mikko P. Pakarinen (778133)   +6 more
core   +1 more source