Results 121 to 130 of about 263,980 (286)
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
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Cellular and Molecular Gastroenterology and Hepatology, 2018 The successful culture of intestinal organoids has greatly enhanced our understanding of intestinal stem cell physiology and enabled the generation of novel intestinal disease models. Although of tremendous value, intestinal organoid culture systems have
Yuli Wang +9 more
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FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Clinical and Experimental Gastroenterology, 2009 Plauto Beck1, George C Mayne1, David Astill2, Tanya Irvine1, David I Watson1, Willem A Dijckmeester1, Bas PL Wijnhoven1, Damian J Hussey11Department of Surgery, 2Department of Anatomical Pathology, Flinders University, Flinders Medical Centre, Bedford ...
Plauto Beck +5 more
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Cdx2 regulates patterning of the intestinal epithelium
Developmental Biology, 2010 Cdx1, Cdx2 and Cdx4 encode homeodomain transcription factors that are involved in vertebral anterior-posterior (AP) patterning. Cdx1 and Cdx2 are also expressed in the intestinal epithelium during development, suggesting a role in this tissue. Intestinal defects have not been reported in Cdx1 null mutants, while Cdx2 null mutants die at embryonic day 3.
Grainger, Stephanie +2 more
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Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion
FEBS Open Bio, EarlyView.Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng +2 more
wiley +1 more source
mSphere, 2016 Despite serving as the primary entry portal for coxsackievirus B (CVB), little is known about CVB infection of the intestinal epithelium, owing at least in part to the lack of suitable in vivo models and the inability of cultured cells to recapitulate ...
Coyne G. Drummond +2 more
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The Ultrastructure of Normal Chick Intestinal Epithelium
Poultry Science, 1974 Abstract Duodenal, jejunal and ileal mucosa of chicks, four to seven weeks old, were embedded in Epon-812 for examination by conventional electron microscopic procedures. A portion of the embedded tissues was also sectioned for examination by light microscopy.
C D, Humphrey, D E, Turk
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Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
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Effect of Deoxynivalenol and Other Type B Trichothecenes on the Intestine: A Review
Toxins, 2014 The natural food contaminants, mycotoxins, are regarded as an important risk factor for human and animal health, as up to 25% of the world’s crop production may be contaminated.
Philippe Pinton, Isabelle P. Oswald
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