Results 161 to 170 of about 188,056 (260)

Intestinal Colonization and Subsequent Nosocomial Infection with Carbapenem-Resistant Organisms in a PICU: Risk Factors and Molecular Homology Analysis. [PDF]

Infect Drug Resist
Yan G, Yang Y, Liu L, Yang W, He L, Wang Y, Zhou J, Chen W, Zhang Y, Zhang C, Fu P, Wang C, Lu G.   +12 more
europepmc   +1 more source

m6A‐Mediated Glycolysis by IL‐37 Drives T Cell Metabolic Reprogramming to Regulate Colitis

Advanced Science, EarlyView.
This study identifies an IL‐37/SIGIRR‐METTL14 regulatory axis that suppresses global m6A modification in CD4+ T cells. IL‐37 signaling, mediated through SIGIRR, inhibits IRAK4 and JNK phosphorylation, leading to downregulation of the methyltransferase METTL14.
Xiaoyan Wang, Jiadong Yu, Guolin Li, Ya Li, Fanlian Zeng, Jing Hu, Yifan Zhou, Chengcheng Yue, Qixiang Zhao, Chen Zhang, Hong Zhou, Fulei Zhao, Yawen Hu, Pei Zhou, Linna Gu, Yuting Feng, Mingxiang He, Shishi Huang, Xiaochi Sun, Xinmeng Wang, Jie Tang, Xinyu Zeng, Wenling Wu, Nongyu Huang, Xinai Cui, Kaijun Cui, Jiong Li   +26 more
wiley   +1 more source

Concurrent infection with piscine intestinal coccidia and infectious spleen and kidney necrosis virus associated with mass mortality and severe gastrointestinal pathology in juvenile <i>Lates calcarifer</i>. [PDF]

Vet World
Suyapoh W, Jantrakajorn S, Pinpimai K, Yostawonkul J, Angsujinda K, Daewang N, Assavalapsakul W, Pirarat N.   +7 more
europepmc   +1 more source

Single‐Cell Dissection of Therapy‐Induced Remodeling Uncovers a Fibroblast‐Driven Immunosuppressive Niche and Targetable Vulnerabilities in Lethal Prostate Cancer

Advanced Science, EarlyView.
Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen, Dandan Dong, Jinling Liao, Naikai Liao, Mengqi Liu, Qin Zhang, Siting Chen, Qi Liu, Ying Lu, Tianyu Li, Chunlin Zou, Qiong Song, Qiuyan Wang, Jian Liang, Qiji Xie, Chengyang Li, Mengyun Wang, Jiwen Cheng, Zengnan Mo, Gong‐Hong Wei   +19 more
wiley   +1 more source

Correlation between fecal eosinophil cationic protein and cow's milk protein allergy in extremely preterm infants and its value in auxiliary diagnosis. [PDF]

Sci Rep
Jin H, Chen Y, Lin Y, Lin Y, Zhuang D, Liu X.   +5 more
europepmc   +1 more source

Unveiling Lactylation: A Novel Frontier in Cancer Stemness and Therapy

Advanced Science, EarlyView.
Tumor metabolism and epigenetic regulation are intrinsically linked. This review highlights lactylation as a pivotal bridge connecting these processes, acting as an active epigenetic effector in cancer stemness. We delineate how lactylation orchestrates the cancer stem cell landscape and evaluate its regulatory networks.
Ting Li, Hongyu Gu, Chang Liu, Yuesheng Lv, Feifei Li, Liang Liang, Jia Yi, Xuanyi Wang, Yi Zhun Zhu, Chuan Xu   +9 more
wiley   +1 more source

Trends in incidence and DALYs of infectious disease from 2000 to 2023 and the attributable risk factors in China: an analysis of the Global Burden of Disease Study 2023. [PDF]

Lancet Reg Health West Pac
Zhou L, Liu Q, Wang Y, Du M, Qin C, Li X, Yan W, Zhang S, Chen W, Wu S, Zhang Z, Zhou L, Hao Y, Cao Z, Luo S, Yang W, Liang W, Liu M, Liu J.   +18 more
europepmc   +1 more source

Correspondence for infectious diseases under infectious diseases '99 "infectious disease new law" . III. Typology of infectious disease Concept of disease and correspondence. 3. Class 3 infectious disease Intestinal hemorrhagic Escherichia coli infectious disease.

Nihon Naika Gakkai Zasshi, 1999
openaire   +2 more sources

Bifidobacterium Pseudolongum‐Derived Inosine Mitigates Polystyrene Nanoplastics‐Induced Hepatic Injury by Inhibiting the Polarization of M1 Macrophages

Advanced Science, EarlyView.
Probiotic B.p colonization elevated gut‐derived inosine level in the liver, while elevated inosine activated A2AR and subsequently blocked NPs‐induced polarization of M1 macrophages by repressing the miR155/SOCS1/NF‐κB pathway. This reduced the release of inflammatory cytokines and thereby, mitigated NPs‐induced hepatic injury.
Kaikai Zhang, Yuchuan Chen, Jiayuan Wan, Jianzheng Yang, Lijian Chen, Qingyuan Li, Anding Zhou, Nian Zhou, Jiuyang Ding, Qi Wang, Jian Sun   +10 more
wiley   +1 more source

Epidemic trends and characteristics of notifiable infectious diseases in mainland China during the COVID-19: a nationwide surveillance study, 2020-2024. [PDF]

J Glob Health
Xu J, Xu Y, Dai Z, Xu Z, Cai H, Zhao Z, Shang W, Dang Y.   +7 more
europepmc   +1 more source