Results 61 to 70 of about 278,744 (336)

Community study of infectious intestinal disease in England [PDF]

BMJ, 1999
Editor—Wheeler et al’s paper estimates the burden of symptomatic infectious intestinal disease in the United Kingdom.1 One aspect of their findings was the high proportion (55%) of community episodes in which no pathogen was identified. I would suggest that this study severely underestimates the prevalence of certain intestinal pathogens.
P. R Hunter, J. G Wheeler, L. C Rodrigues, D. Sethi, D. S Tompkins, M. J Hudson, P. J Roderick, J. M Cowden, P. G Wall   +8 more
openaire   +4 more sources

Mendelian randomization and bioinformatics unveil potential links between gut microbial genera and colorectal cancer

Frontiers in Genetics
BackgroundColorectal cancer (CRC) poses a significant global health burden, with high incidence and mortality rates. Despite advances in diagnostic and therapeutic modalities, early diagnosis remains critical for improved outcomes.
Long Wu, Huan Wu, Fei Huang, Song Mu, Xiao-Yun Li, Bao-Fang Zhang, Yun-Huan Zhen, Hai-Yang Li   +7 more
doaj   +1 more source

Current Status of Phage Therapy against Infectious Diseases and Potential Application beyond Infectious Diseases

International Journal of Clinical Practice, 2022
Intestinal microbiota plays a key role in regulating the pathogenesis of human disease and maintaining health. Many diseases, mainly induced by bacteria, are on the rise due to the emergence of antibiotic-resistant strains.
Hao-Ming Xu, Wen-Min Xu, Long Zhang
doaj   +1 more source

The therapeutic management of gut barrier leaking: the emerging role for mucosal barrier protectors [PDF]

, 2015
OBJECTIVE: Gut barrier is a functional unit organized as a multi-layer system and its multiple functions are crucial for maintaining gut homeostasis. Numerous scientific evidences showed a significant association between gut barrier leaking and gastro ...
Bruno, G, Franceschi, F, Gasbarrini, A, Lopetuso, Lr, Petito, V, Scaldaferri, F   +5 more
core  

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Global burden of malaria before and after the COVID-19 pandemic based on the global burden of disease study 2021

Scientific Reports
Malaria poses significant public health challenges and huge disease and economic burdens across the world, notably in low-income countries. Although great strides have been achieved, the COVID-19 pandemic hinders the progress towards global elimination ...
Jiaofeng Huang, Yuekai Hu, Yinlian Wu, Li Pan, Mingfang Wang, Wei Wang, Su Lin   +6 more
doaj   +1 more source

Estimating the Incidence of Acute Infectious Intestinal Disease in the Community in the UK: A Retrospective Telephone Survey [PDF]

PLOS ONE, 2016
To estimate the burden of intestinal infectious disease (IID) in the UK and determine whether disease burden estimations using a retrospective study design differ from those using a prospective study design.A retrospective telephone survey undertaken in each of the four countries comprising the United Kingdom.
Laura Viviani, Mike van der Es, Lisa Irvine, Clarence C Tam, Laura C Rodrigues, Kathryn A Jackson, Sarah J O'Brien, Paul R Hunter, IID2 Study Executive Committee   +8 more
openaire   +7 more sources

Acute intestinal infections in children [PDF]

, 2013
Acute intestinal infections - a large group of human infectious diseases caused by pathogenic and opportunistic bacteria, viruses and protozoa. Intestinal infections until now occupy a leading position in infectious diseases, especially in childhood ...
Smiyan, K.O.
core  

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Infectious intestinal disease : do we know it all? [PDF]

, 2006
Infectious intestinal disease (IID), with associated high morbidity and considerable mortality worldwide, causes a wide spectrum of illness. This ranges from mild discomfort to illness with severe complications.
Gauci, Charmaine, Gilles, Herbert M., Mamo, Julian, O’Brien, Sarah J.   +3 more
core