Results 51 to 60 of about 317,603 (310)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Differences in virus receptor for type I and type II feline infectious peritonitis virus. [PDF]

, 1998
Feline infectious peritonitis viruses (FIPVs) are classified into type I and type II serogroups. Here, we report that feline aminopeptidase N (APN), a cell-surface metalloprotease on the intestinal, lung and kidney epithelial cells, is a receptor for ...
Hohdatsu, T, Izumiya, Y, Kida, K, Koyama, H, Yokoyama, Y   +4 more
core  

Impact of Experimental Hookworm Infection on the Human Gut Microbiota [PDF]

, 2014
The interactions between gastrointestinal parasitic helminths and commensal bacteria are likely to play a pivotal role in the establishment of host-parasite cross-talk, ultimately shaping the development of the intestinal immune system.
Alex Loukas, Broadhurst, Caporaso, Cinzia Cantacessi, Cooper, Croese, Croese, Daveson, Gaze, Javier Sotillo, John Croese, Kumar, Leisa McCann, Li, Lutz Krause, Makedonka Mitreva, Martha Zakrzewski, Matthew J. Nolan, Muyzer, Paul Giacomin, Round, Sepehri, Summers, Walk, Yazdanbakhsh   +24 more
core   +3 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Intestinal Microbiome in Hematopoietic Stem Cell Transplantation For Autoimmune Diseases: Considerations and Perspectives on Behalf of Autoimmune Diseases Working Party (ADWP) of the EBMT

Frontiers in Oncology, 2021
Over the past decades, hematopoietic stem cell transplantation (HSCT) has been evolving as specific treatment for patients with severe and refractory autoimmune diseases (ADs), where mechanistic studies have provided evidence for a profound immune ...
Tobias Alexander, Tobias Alexander, John A. Snowden, John A. Snowden, Joachim Burman, Hyun-Dong Chang, Hyun-Dong Chang, Nicoletta Del Papa, Dominique Farge, Dominique Farge, Dominique Farge, James O. Lindsay, Florent Malard, Paolo A. Muraro, Rosamaria Nitti, Azucena Salas, Basil Sharrack, Basil Sharrack, Mohamad Mohty, Raffaella Greco   +19 more
doaj   +1 more source

Porcine innate and adaptative immune responses to influenza and coronavirus infections [PDF]

, 2006
Both innate and adaptative immune responses contribute to the control of infectious diseases, including by limiting the spreading of zoonotic diseases from animal reservoirs to humans.
Asselin-Paturel, Baudoux, BERNARD CHARLEY, Brim, Charley, Charley, Charley, Chen, Chinsangaram, Corthier, Fitzgerald-Bocarsly, Guzylack-Piriou, Heinen, KRISTIEN VAN REETH, La Bonnardière, Laude, Laude, Le Bon, Lim, Liu, Palese, Peiris, Pestka, Riffault, Riffault, Riffault, Rothenfusser, SABINE RIFFAULT, Saif, Siegal, Summerfield, Tu, Tudor, Van Reeth, Van Reeth, van Reeth   +35 more
core   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Microbiota and hepatic diseases

Лечащий Врач, 2021
The data on the existing knowledge in the field of intestinal microbiota influence on human diseases were presented, in particular, non-alcoholic fat liver disease, alcoholic liver disease, inflammatory intestinal diseases and infectious gastrointestinal
T. E. Polunina
doaj  

Acute intestinal infections in children [PDF]

, 2013
Acute intestinal infections - a large group of human infectious diseases caused by pathogenic and opportunistic bacteria, viruses and protozoa. Intestinal infections until now occupy a leading position in infectious diseases, especially in childhood ...
Smiyan, K.O.
core  

Murine fecal microbiota transplantation lowers gastrointestinal pathogen loads and dampens pro-inflammatory immune responses in Campylobacter jejuni infected secondary abiotic mice [PDF]

, 2019
Conventional mice are protected from Campylobacter jejuni infection by the murine host-specific gut microbiota composition. We here addressed whether peroral fecal microbiota transplantation (FMT) might be an antibiotics-independent option to lower even ...
Bereswill, Stefan, Heimesaat, Markus M., Mrazek, Katharina   +2 more
core   +1 more source