Results 51 to 60 of about 2,641,131 (261)

mTOR signalling controls the formation of smooth muscle cell-derived luminal myofibroblasts during vasculitis

EMBO Reports
The accumulation of myofibroblasts within the intimal layer of inflamed blood vessels is a potentially catastrophic complication of vasculitis, which can lead to arterial stenosis and ischaemia.
Angus T Stock, Sarah Parsons, Jacinta A Hansen, Damian B D’Silva, Graham Starkey, Aly Fayed, Xin Yi Lim, Rohit D’Costa, Claire L Gordon, Ian P Wicks   +9 more
doaj   +1 more source

Surveillance and response systems for elimination of tropical diseases : summary of a thematic series in infectious diseases of poverty [PDF]

, 2016
The peer-reviewed journal Infectious Diseases of Poverty provides a new platform to engage with, and disseminate in an open-access format, science outside traditional disciplinary boundaries.
Zhou, Xiao-Nong, Xiao-Nong Zhou (92570), Yap, Peiling, Utzinger, Jürg, Robert Bergquist (377449), Xia Zhou (291729), Zhou, Xia, Bergquist, Robert, Peiling Yap (596280), Marcel Tanner (33894), JĂźrg Utzinger (3428396), Tanner, Marcel   +11 more
core   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Mendelian randomization and bioinformatics unveil potential links between gut microbial genera and colorectal cancer

Frontiers in Genetics
BackgroundColorectal cancer (CRC) poses a significant global health burden, with high incidence and mortality rates. Despite advances in diagnostic and therapeutic modalities, early diagnosis remains critical for improved outcomes.
Long Wu, Huan Wu, Fei Huang, Song Mu, Xiao-Yun Li, Bao-Fang Zhang, Yun-Huan Zhen, Hai-Yang Li   +7 more
doaj   +1 more source

Evaluation of the Mechanisms Underlying Amino Acid and Microbiota Interactions in Intestinal Infections Using Germ-Free Animals

Infectious Microbes & Diseases, 2021
. Intestinal infectious diseases refer to the inflammatory changes in the intestinal tract caused by pathogens (including bacteria, viruses, fungi, protozoa, or parasites) or their toxic products.
Yapeng Yang, Peng Bin, Shiyu Tao, Guoqiang Zhu, Zhifeng Wu, Wei Cheng, Wenkai Ren, Hong Wei, Fudi Wang   +8 more
doaj   +1 more source

The epidemiology of norovirus in England diagnostics, incidence and transmission [PDF]

Existing estimates of the incidence of infectious intestinal disease (IID) caused by norovirus in the community are based on electron microscopy or reverse transcription- polymerase chain reaction (RT-PCR).
Phillips, Gemma
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Infectious intestinal disease : do we know it all? [PDF]

, 2006
Infectious intestinal disease (IID), with associated high morbidity and considerable mortality worldwide, causes a wide spectrum of illness. This ranges from mild discomfort to illness with severe complications.
Gauci, Charmaine, Mamo, Julian, Gilles, Herbert M., O’Brien, Sarah J.   +3 more
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Intestinal microbiota of patients with bacterial infection of the respiratory tract treated with amoxicillin

, 2005
The intestinal tract harbors a huge diversity of metabolically-active aerobic and anaerobic bacteria that interact, forming a complex ecosystem. This microbiota has an important role in human metabolism, nutrition, immunity, and protection against ...
Lopes, Carlos Alberto De Magalhães [UNESP], Monreal, Maria Tereza Ferreira Duenhas, Pereira, Paulo Câmara Marques [UNESP]   +2 more
core   +1 more source