Results 61 to 70 of about 2,641,131 (261)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Microbiota and hepatic diseases

Лечащий Врач, 2021
The data on the existing knowledge in the field of intestinal microbiota influence on human diseases were presented, in particular, non-alcoholic fat liver disease, alcoholic liver disease, inflammatory intestinal diseases and infectious gastrointestinal
T. E. Polunina
doaj  

HIV and intestinal parasite co-infections among a Chinese population : an immunological profile [PDF]

, 2013
Parasite infections often result in a switch of the human body's predominant immune reaction from T-helper 1 (Th1)-type to Th2-type. Hence, parasite infections are widely expected to accelerate the progression of human immunodeficiency virus (HIV ...
Wang, Feng-Feng, Peter Steinmann, Xiao-Mei Yin, Tian, Li-Guang, Jian Guo, Cai, Yu-Chun, Mary Dickey, Jia-Xu Chen, Dickey, Mary Kathryn, Li-Guang Tian, Shan Lv, Yu-Chun Cai, Steinmann, Peter, Guo, Jian, Chen, Jia-Xu, Feng-Feng Wang, Lv, Shan, Wang, Tian-Ping, Yin, Xiao-Mei, Tian-Ping Wang   +19 more
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Changes in reported cases and distribution of infectious disease under the grading diagnosis and treatment model in Minhang District， Shanghai

Shanghai yufang yixue
Objective To analyze the reported cases of infectious diseases across different tiers of public medical and healthcare institutions in Minhang District, Shanghai from 2013 to 2023, to investigate the status and changes in reported infectious diseases
CHEN Long, DONG Linjuan, ZHOU Yibin, CHENG Tingqin, WANG Dunjia, XU Zhiyin, CHEN Wanli, ZHONG Wei, LIU Xiaohua   +8 more
doaj   +1 more source

Intestinal Microbiome in Hematopoietic Stem Cell Transplantation For Autoimmune Diseases: Considerations and Perspectives on Behalf of Autoimmune Diseases Working Party (ADWP) of the EBMT

Frontiers in Oncology, 2021
Over the past decades, hematopoietic stem cell transplantation (HSCT) has been evolving as specific treatment for patients with severe and refractory autoimmune diseases (ADs), where mechanistic studies have provided evidence for a profound immune ...
Tobias Alexander, Tobias Alexander, John A. Snowden, John A. Snowden, Joachim Burman, Hyun-Dong Chang, Hyun-Dong Chang, Nicoletta Del Papa, Dominique Farge, Dominique Farge, Dominique Farge, James O. Lindsay, Florent Malard, Paolo A. Muraro, Rosamaria Nitti, Azucena Salas, Basil Sharrack, Basil Sharrack, Mohamad Mohty, Raffaella Greco   +19 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Sentinel Surveillance: an option for surveillance of infectious intestinal disease

Eurosurveillance, 2007
Binary file ES_Abstracts_Final_ECDC.txt matches
Gauci, C., Melillo Fenech, T., Gilles, H., O'Brien, S., Mamo, J., Stabile, I., Calleja, N., Ruggeri, F., Cuschieri, L.   +8 more
openaire   +4 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Sheep Movement Networks and the Transmission of Infectious Diseases [PDF]

, 2010
Background and Methodology: Various approaches have been used to investigate how properties of farm contact networks impact on the transmission of infectious diseases.
Nicholas J. Savill, Nicholas J Savill, Woolhouse Mark E. J., Mark E J Woolhouse, Volkova Victoriya V., Savill, Nicholas J., Howey Richard, Savill Nicholas J., Mark E. J. Woolhouse, Howey, Richard, Victoriya V Volkova, Victoriya V. Volkova, Volkova, Victoriya V., Richard Howey, Woolhouse, Mark E. J.; id_orcid   +14 more
core   +2 more sources