Results 81 to 90 of about 670,134 (326)

Automated Infectious Disease Forecasting: Use-cases and Practical Considerations for Pipeline Implementation [PDF]

arXiv, 2022
Real-time forecasting of disease outbreaks requires standardized outputs generated in a timely manner. Development of pipelines to automate infectious disease forecasts can ensure that parameterization and software dependencies are common to any execution of the forecasting code.
arxiv  

Socioeconomic status and infectious intestinal disease in the community: a longitudinal study (IID2 study) [PDF]

European Journal of Public Health, 2017
Infectious intestinal diseases (IID) are common, affecting around 25% of people in UK each year at an estimated annual cost to the economy, individuals and the NHS of £1.5 billion. While there is evidence of higher IID hospital admissions in more disadvantaged groups, the association between socioeconomic status (SES) and risk of IID remains unclear ...
Mara Violato, Tanith C. Rose, Sarah J. O'Brien, David Taylor-Robinson, Jeremy Hawker, Benjamin Barr, Margaret Whitehead, Natalie L. Adams, Natalie L. Adams   +8 more
openaire   +5 more sources

Community study of infectious intestinal disease in England [PDF]

BMJ, 1999
Editor—Wheeler et al’s paper estimates the burden of symptomatic infectious intestinal disease in the United Kingdom.1 One aspect of their findings was the high proportion (55%) of community episodes in which no pathogen was identified. I would suggest that this study severely underestimates the prevalence of certain intestinal pathogens.
P. R Hunter, J. G Wheeler, L. C Rodrigues, D. Sethi, D. S Tompkins, M. J Hudson, P. J Roderick, J. M Cowden, P. G Wall   +8 more
openaire   +4 more sources

Mendelian randomization and bioinformatics unveil potential links between gut microbial genera and colorectal cancer

Frontiers in Genetics
BackgroundColorectal cancer (CRC) poses a significant global health burden, with high incidence and mortality rates. Despite advances in diagnostic and therapeutic modalities, early diagnosis remains critical for improved outcomes.
Long Wu, Huan Wu, Fei Huang, Song Mu, Xiao-Yun Li, Bao-Fang Zhang, Yun-Huan Zhen, Hai-Yang Li   +7 more
doaj   +1 more source

Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases

FEBS Letters, EarlyView.
The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher, Paula Armina V. Buco, Jia Q. Truong, Paul A. Ramsland, Monique F. Smeets, Carl R. Walkley, Jessica K. Holien   +6 more
wiley   +1 more source

Channel Capacity of Starch and Glucose Molecular Communications in the Small Intestine Digestive Tract [PDF]

arXiv, 2021
The emerging field of Molecular Communication (MC) aims to characterize biological-based signaling environment through information that are encoded into molecules. Since the birth of this field, a number of different applications and biological systems have been characterized using MC theory.
arxiv  

[Retracted] Effects of Irrational Use of Antibiotics on Intestinal Health of Children with Extraintestinal Infectious Diseases

Contrast Media & Molecular Imaging, 2022
The effects of different antibiotic treatment regimens on intestinal function and flora distribution in children with extraintestinal infectious diseases are explored. A total of 150 cases of extraintestinal infectious diseases admitted to our hospital from January 2021 to January 2022 and 50 healthy subjects during the same period were selected for ...
Xiaomei Guo, Lifu Sun, Shengjiang Wang, Yan Shen   +3 more
openaire   +2 more sources

Emerging Role of Exosomes in Diagnosis and Treatment of Infectious and Inflammatory Bowel Diseases

Cells, 2020
To communicate with each other, cells release exosomes that transfer their composition, including lipids, proteins and nucleic acids, to neighboring cells, thus playing a role in various pathophysiological processes.
Anaïs Larabi, N. Barnich, H. Nguyen
semanticscholar   +1 more source

The multiple roles of the NlpC_P60 peptidase family in mycobacteria – an underexplored target for antimicrobial drug discovery

FEBS Letters, EarlyView.
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva, Marcio Vinicius Bertacine Dias   +1 more
wiley   +1 more source

Intestinal Microbiome in Hematopoietic Stem Cell Transplantation For Autoimmune Diseases: Considerations and Perspectives on Behalf of Autoimmune Diseases Working Party (ADWP) of the EBMT

Frontiers in Oncology, 2021
Over the past decades, hematopoietic stem cell transplantation (HSCT) has been evolving as specific treatment for patients with severe and refractory autoimmune diseases (ADs), where mechanistic studies have provided evidence for a profound immune ...
Tobias Alexander, Tobias Alexander, John A. Snowden, John A. Snowden, Joachim Burman, Hyun-Dong Chang, Hyun-Dong Chang, Nicoletta Del Papa, Dominique Farge, Dominique Farge, Dominique Farge, James O. Lindsay, Florent Malard, Paolo A. Muraro, Rosamaria Nitti, Azucena Salas, Basil Sharrack, Basil Sharrack, Mohamad Mohty, Raffaella Greco   +19 more
doaj   +1 more source