Results 251 to 260 of about 596,920 (286)

Itaconate suppresses neonatal intestinal inflammation via metabolic reprogramming of M1 macrophage. [PDF]

Clin Transl Med
Huangfu S, Lan C, Li S, Wang H, Yan C, Yang Y, Tian B, Mu Y, Zhao P, Tian Y, Wang Y, Zhong W, Zhong L, Shi Y, Liu Y.   +14 more
europepmc   +1 more source

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

Dysregulation of cellular metabolism within the gut-brain axis is associated with behavioural changes in chronic intestinal inflammation. [PDF]

J Neuroinflammation
Devereaux J, Robinson AM, Stavely R, Davidson M, Filippone RT, Ephraim R, Kiatos D, Apostolopoulos V, Nurgali K.   +8 more
europepmc   +1 more source

Atomic Size Misfit for Electrocatalytic Small Molecule Activation

Advanced Functional Materials, EarlyView.
This review explores the application and mechanisms of atomic size misfit in catalysis for small molecule activation, focusing on how structural defects and electronic properties can effectively lower the energy barriers of chemical bonds in molecules like H2O, CO2, and N2.
Ping Hong, Changfan Xu, Huaping Zhao, Yong Lei   +3 more
wiley   +1 more source

2D Multifunctional Spin‐Orbit Coupled Dirac Nodal Line Materials

Advanced Functional Materials, EarlyView.
A total of 473 nonmagnetic and antiferromagnetic 2D spin‐orbit coupled Dirac nodal line materials are screened, spanning 5 layer groups and 12 magnetic space groups. Furthermore, it integrates their topological properties with electride, multiferroic, and magnetic characteristics, revealing unique systems with expanded functionalities and promising ...
Weizhen Meng, Ying Liu, Jialin Gong, Yalong Jiao, Xiaoming Zhang, Wenxian Li, Zhenxiang Cheng, Tie Yang   +7 more
wiley   +1 more source

Molecular Characterization and Pathogenicity of a Novel Recombinant NADC30-Like PRRSV Strain Isolated From Piglets Inducing Intestinal Inflammation, and Construction of Its Infectious Clone. [PDF]

Transbound Emerg Dis
Lin Y, Ouyang Y, Zheng J, Xiao C, Yang Y, Zhao Q, Zhang Y, Li Z, Liu K, Li B, Shao D, Qiu Y, Ma Z, Wei J.   +13 more
europepmc   +1 more source

Kinetic Insights into Precursor‐Assisted Soft Sphere Close Packing Revealed by In Situ GISAXS with Implications for Gas Sensing

Advanced Functional Materials, EarlyView.
The versatile precursor‐assisted soft sphere close packing during slot‐die coating is investigated with in situ X‐ray scattering. The soft crystallization pathways towards a close packing involve multistep structural transitions such as surface nucleation, in‐plane, and out‐of‐plane crystallization.
Guangjiu Pan, Wenhe Xie, Suzhe Liang, Ting Tian, Shanshan Yin, Lixing Li, Altantulga Buyan‐Arivjikh, Jinsheng Zhang, Thomas Baier, Zhuijun Xu, Matthias Schwartzkopf, Sarathlal Koyiloth Vayalil, Stephan V. Roth, Yonghui Deng, Peter Müller‐Buschbaum   +14 more
wiley   +1 more source

Macrophage-Mediated Transport of Insoluble Indirubin Induces Hepatic Injury During Intestinal Inflammation. [PDF]

Adv Sci (Weinh)
Xu Y, Shi J, Mok HL, Lyu C, Chen J, Huang C, Qin H, Lin C, Tan HY, Bian Z.   +9 more
europepmc   +1 more source

Giardia-induced Type 2 mucosal immunity attenuates intestinal inflammation caused by co-infection or colitis in mice. [PDF]

Nat Microbiol
Sardinha-Silva A, Gazzinelli-Guimaraes PH, Ajakaye OG, Oliveira FMS, Ferreira TR, Alves-Ferreira EVC, Tjhin ET, Gregg B, Fink MY, Coelho CH, Singer SM, Grigg ME.   +11 more
europepmc   +1 more source

Peroxiredoxin 1 promotes intestinal inflammation by activating the NLRP3 inflammasome in macrophages through lysosomal disruption in Crohn's disease. [PDF]

Cell Death Dis
Li S, Xia Q, He Y, Wu W, Tang D, Deng Z, Zeng Z, Tu S, Chen B, Gu L, Yang X, Peng Y, Yang H, Peng Z.   +13 more
europepmc   +1 more source