Results 31 to 40 of about 596,920 (286)

Role of subclinical gut inflammation in the pathogenesis of spondyloarthritis [PDF]

open access: yes, 2018
Subclinical gut inflammation occurring in patients affected by spondyloarthritis (SpA) is correlated with the severity of spine inflammation. Several evidences indicate that dysbiosis occurs in SpA, and that may modulate intestinal permeability and ...
Ciccia F.   +3 more
core   +1 more source

Intestinal inflammation in cystic fibrosis [PDF]

open access: yesArchives of Disease in Childhood, 2000
There is controversy about whether the inflammatory response observed in the cystic fibrosis (CF) lung occurs secondary to bacterial infection or is caused by a dysregulation of the inflammatory response associated with the basic cellular defect of CF.To study the inflammatory response in the gastrointestinal tract of children with CF; and to ...
R L, Smyth   +4 more
openaire   +2 more sources

Experimental Evaluation of the Impact of Gadolinium Orthovanadate GdVO4:Eu3+ Nanoparticles on the Carrageenan-Induced Intestinal Inflammation

open access: yesActa Medica, 2020
Aim: To evaluate the effects of orally administered gadolinium orthovanadate GdVO4:Eu3+ nanoparticles (VNPs) on the course of chronic carrageenan-induced intestinal inflammation. Methods: Samples of small intestinal tissue were collected from four groups
Anton S. Tkachenko   +6 more
doaj   +1 more source

Dysregulation of CD177+ neutrophils on intraepithelial lymphocytes exacerbates gut inflammation via decreasing microbiota-derived DMF

open access: yesGut Microbes, 2023
Neutrophils synergize with intestinal resident intraepithelial lymphocytes (IELs) to serve as the first-line defense and maintain intestinal homeostasis.
Huimin Chen   +11 more
doaj   +1 more source

Peroxisome proliferator‐activated receptor gamma (PPARγ) regulates lactase expression and activity in the gut

open access: yesEMBO Molecular Medicine, 2017
Lactase (LCT) deficiency affects approximately 75% of the world's adult population and may lead to lactose malabsorption and intolerance. Currently, the regulation of LCT gene expression remains poorly known.
Mathurin Fumery   +13 more
doaj   +1 more source

Alveolar macrophages and Toll-like receptor 4 mediate ventilated lung ischemia reperfusion injury in mice. [PDF]

open access: yes, 2012
BackgroundIschemia-reperfusion (I-R) injury is a sterile inflammatory process that is commonly associated with diverse clinical situations such as hemorrhage followed by resuscitation, transient embolic events, and organ transplantation.
Dodd-o, Jeffrey M   +5 more
core   +1 more source

Intestinal Macrophages in Resolving Inflammation [PDF]

open access: yesThe Journal of Immunology, 2019
Abstract Macrophages not only regulate intestinal homeostasis by recognizing pathogens to control enteric infections but also employ negative feedback mechanisms to prevent chronic inflammation. Hence, macrophages are intriguing targets for immune-mediated therapies, especially when barrier function in the gut is compromised to trigger ...
Ashley M, Hine, P'ng, Loke
openaire   +2 more sources

Enteric nervous system modulation of luminal pH modifies the microbial environment to promote intestinal health.

open access: yesPLoS Pathogens, 2022
The enteric nervous system (ENS) controls many aspects of intestinal homeostasis, including parameters that shape the habitat of microbial residents.
M Kristina Hamilton   +4 more
doaj   +1 more source

Neutrophils in Intestinal Inflammation: What We Know and What We Could Expect for the Near Future

open access: yesGastrointestinal Disorders, 2022
Neutrophils are short-lived cells that play a crucial role in inflammation. As in other tissues, these polymorphonuclear phagocytes are involved in the intestinal inflammatory response, on the one hand, contributing to the activation and recruitment of ...
Laura Arosa   +2 more
doaj   +1 more source

Vitamin D3 deficiency induced intestinal inflammatory response of turbot through nuclear factor-κB/inflammasome pathway, accompanied by the mutually exclusive apoptosis and autophagy

open access: yesFrontiers in Immunology, 2022
Vitamin D3 (VD3) participated widely in the nuclear factor-κB (NF-κB)-mediated inflammation, apoptosis, and autophagy through the vitamin D receptor (VDR). However, the molecular mechanisms remain not understood in teleost. The present study investigated
Zhichu Chen   +11 more
doaj   +1 more source

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