Results 51 to 60 of about 596,920 (286)

Macrobiota — helminths as active participants and partners of the microbiota in host intestinal homeostasis [PDF]

, 2016
Important insights have recently been gained in our understanding of the intricate relationship in the intestinal milieu between the vertebrate host mucosal immune response, commensal bacteria, and helminths. Helminths are metazoan worms (macrobiota) and
Gause, William C., Maizels, Rick M.
core   +1 more source

Wnt signaling in intestinal inflammation

Differentiation, 2019
Chronic inflammatory bowel diseases, including Crohn's disease and ulcerative colitis, are a major health burden worldwide. Numerous conserved signaling pathways control tissue injury and repair during colitis, but owing to the complexity of the inflammatory process, their individual contribution remains poorly understood.
Moparthi, Lavanya, Koch, Stefan
openaire   +3 more sources

Prebiotics in Chronic Intestinal Inflammation [PDF]

Inflammatory Bowel Diseases, 2009
Prebiotics are nondigestible fermentable fibers that are reported to have health benefits for the host. Older as well as more recent studies show beneficial effects in experimental colitis and lately also in human inflammatory bowel diseases (IBD), such as Crohn's disease, ulcerative colitis, and chronic pouchitis. In this review we give an overview of
Mirjam A C, Looijer-van Langen, Levinus A, Dieleman   +1 more
openaire   +2 more sources

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Intestinal inflammation responds to microbial tissue load independent of pathogen/non-pathogen discrimination. [PDF]

PLoS ONE, 2012
The intestinal immune system mounts inflammatory responses to pathogens but tolerates harmless commensal microbiota. Various mechanisms for pathogen/non-pathogen discrimination have been proposed but their general relevance for inflammation control is ...
Yvonne Willer, Beatrice Müller, Dirk Bumann   +2 more
doaj   +1 more source

Krill oil, vitamin D and Lactobacillus reuteri cooperate to reduce gut inflammation [PDF]

, 2018
Current research into original therapies to treat intestinal inflammation is focusing on no-drug therapies. KLD is a mixture of krill oil (KO), probiotic Lactobacillus reuteri (LR), and vitamin D (VitD3).
Cesi, V., Colantoni, E., Costanzo, M., Cucchiara, S., Leter, B., Negroni, A., Palone, F., Pierdomenico, M., Stronati, L., Vitali, R.   +9 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Oral chondroitin sulfate and prebiotics for the treatment of canine Inflammatory Bowel Disease: a randomized, controlled clinical trial [PDF]

, 2016
BACKGROUND Canine inflammatory bowel disease (IBD) is a chronic enteropathy of unknown etiology, although microbiome dysbiosis, genetic susceptibility, and dietary and/or environmental factors are hypothesized to be involved in its pathogenesis. Since
A Ghiselli, A Tvarijonaviciute, A Wächtershäuser, ABC Samuelsen, AE Jergens, AE Jergens, AJ Schottelius, Alberto Muñoz-Prieto, Alfonso Velasco, Antonio Rodríguez-Bertos, CG Fraga, CS Brennan, D Boehm, D Martínez-Puig, Daniel Martínez-Puig, E Gisbert, Fernando Rodríguez-Franco, G Rossi, G Rossi, IE Koutroubakis, JE Fogle, JJ Ceron, José Cerón, JS Suchodolski, JS Suchodolski, K Allenspach, K Allenspach, Karin Allenspach, KS Swanson, KW Simpson, L Kaufman, M Castillo, M García-Sancho, M Krzystek-Korpacka, M Nofrarías, M Roca, M Volkmann, MA Murphy, Marta Cerdà-Cuéllar, MT Collins, N Luckschander, O Erel, P Souich du, PG Xenoulis, RJ Washabau, S Martinez-Subiela, Sergi Segarra, Silvia Martínez-Subiela, TM McCann, VL Cabral, Y Minamoto, Y You   +51 more
core   +6 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Ochratoxin A induces liver inflammation: involvement of intestinal microbiota

Microbiome, 2019
Background Ochratoxin A (OTA) is a widespread mycotoxin and induces liver inflammation to human and various species of animals. The intestinal microbiota has critical importance in liver inflammation; however, it remains to know whether intestinal ...
Wence Wang, Shuangshuang Zhai, Yaoyao Xia, Hao Wang, Dong Ruan, Ting Zhou, Yongwen Zhu, Hongfu Zhang, Minhong Zhang, Hui Ye, Wenkai Ren, Lin Yang   +11 more
doaj   +1 more source