Results 71 to 80 of about 596,920 (286)
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
PLoS ONE, 2019 Chronic intestinal inflammation contributes to pathologies such as inflammatory bowel disease (IBD) and colon cancer. While the precise etiology remains controversial, IBD is believed to manifest as a result of various factors.
Shaiya C Robinson +6 more
doaj +1 more source
Poultry Science, 2020 Gut inflammation caused by various factors including microbial infection leads to disorder of absorption of dietary nutrients and decrease in egg production in laying hens.
T. Nii, T. Bungo, N. Isobe, Y. Yoshimura
doaj +1 more source
Antrodia cinnamomea reduces obesity and modulates the gut microbiota in high-fat diet-fed mice. [PDF]
, 2018 BackgroundObesity is associated with gut microbiota dysbiosis, disrupted intestinal barrier and chronic inflammation. Given the high and increasing prevalence of obesity worldwide, anti-obesity treatments that are safe, effective and widely available ...
Chang, C-J +11 more
core
The role of the novel Th17 cytokine IL-26 in intestinal inflammation [PDF]
, 2008 Background and aims: Interleukin 26 (IL-26), a novel IL-10-like cytokine without a murine homologue, is expressed in T helper 1 (Th1) and Th17 cells. Currently, its function in human disease is completely unknown. The aim of this study was to analyse its
Auernhammer, Christoph J. +7 more
core +1 more source
Chronic Intestinal Inflammation and Intestinal Disease in Dogs [PDF]
Journal of Veterinary Internal Medicine, 2003 Normal individuals maintain tolerance to the endogenous bacterial flora residing within their alimentary tract, a phenomenon mediated by the gastrointestinal lymphoid tissue. Loss of this tolerance is a key factor in the development of chronic intestinal inflammation. Manifestations of such uncontrolled inflammation in humans include inflammatory bowel
A J, German, E J, Hall, M J, Day
openaire +2 more sources
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Effects of Aroclor 1254 on Intestinal Immunity, Metabolism, and Microflora in Zebrafish
Frontiers in Nutrition, 2022 Polychlorinated biphenyls (PCBs) are widely distributed environmental toxicants, whose biological toxicity is magnified step by step through the transmission of the food chain.
Di-Hua Zhu +9 more
doaj +1 more source
In situ PCR for Mycobacterium tuberculosis in endoscopic mucosal biopsy specimens of intestinal tuberculosis and Crohn disease [PDF]
, 2008 Tuberculosis and Crohn disease are granulomatous disorders affecting the intestinal tract with similar clinical manifestations and pathologic features.
Donoghue, HD +3 more
core +1 more source
Intestinal stasis associated bowel inflammation
World Journal of Gastroenterology, 1999 Anatomical structures that create reservoirs for stagnant intestinal contents are a characteristic feature of common inflammatory disorders such as diverticulitis and appendicitis. Intestinal diverticula, surgically constructed blind loops and pouches, obstructing carcinomas of the colon, and Hirschsprung’s disease are accompanied by chronic ...
Shunichiro, Komatsu +2 more
openaire +2 more sources