Results 41 to 50 of about 588,404 (299)

Evaluating Remote Ischemic Conditioning in a Rat Model of Intestinal Ischemia Reperfusion: A Study Highlighting Experimental Model Limitations

Journal of Indian Association of Pediatric Surgeons
Context: Remote ischemic conditioning (RIC) protects distant organs from ischemia-reperfusion injury (IRI) through brief, nonlethal ischemic episodes. In pediatric intestinal IRI, such as in midgut volvulus and necrotizing enterocolitis, RIC may enhance ...
Apurva Gupta, Manish Pathak, Poonam Elhence, Tripti Sharma, Prasunpriya Nayak, Ravisekhar Gadepalli, Shailja Sharma, Avinash S Jadhav, Shubhalaxmi Nayak, Kirtikumar J Rathod, Rahul Saxena, Arvind Sinha   +11 more
doaj   +1 more source

ROENTGENOGRAPHIC ASPECTS OF INTESTINAL ISCHEMIA [PDF]

American Journal of Roentgenology, 1972
Until recent years, the general concept of vascular disease involving the intestine was of overwhelming infarction leading to rapid death unless corrected surgically. While this type of involvement may occur, there has been increasing recognition of a whole spectrum of intestinal ischemic states. Some are mild and chronic. Longstanding symptoms such as
S L, Smith, R H, Tutton, S F, Ochsner
openaire   +2 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Ischemic preconditioning and the gene expression of enteric endothelial cell biology of rats submitted to intestinal ischemia and reperfusion [PDF]

Acta Cirúrgica Brasileira, 2013
PURPOSE: To investigate the effects of ischemic preconditioning (IPC) on the expression of pro and anti-apoptotic genes in rat endothelial cells undergoing enteric ischemia (I) and reperfusion (R).
Murched Omar Taha, Regiane Miranda Ferreira, Nabiha Saadi Abrahão Taha, Hugo Pequeno Monteiro, Afonso Caricati-Neto, Itamar Souza Oliveira-Júnior, Djalma José Fagundes   +6 more
doaj   +3 more sources

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Monitoring of lung edema by microwave reflectometry during lung ischemia-reperfusion injury in vivo [PDF]

, 2006
It is still unclear whether lung edema can be monitored by microwave reflectometry and whether the measured changes in lung dry matter content (DMC) are accompanied by changes in PaO(2) and in pro-to anti-inflammatory cytokine expression (IFN-gamma and ...
Metzger, R. P., Gross, W., Nowak, K., Schaefer, M., Post, S., Gebhard, M. M., Hohenberger, P.   +6 more
core   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng, Diego Z. Carvalho, Shahid Karim, Anwar Chahal, Virend K. Somers   +4 more
wiley   +1 more source

Small intestinal viability assessment using dielectric relaxation spectroscopy and deep learning

Scientific Reports, 2022
Intestinal ischemia is a serious condition where the surgeon often has to make important but difficult decisions regarding resections and resection margins. Previous studies have shown that 3 h (hours) of warm full ischemia of the small bowel followed by
Jie Hou, Runar Strand-Amundsen, Christian Tronstad, Tor Inge Tønnessen, Jan Olav Høgetveit, Ørjan Grøttem Martinsen   +5 more
doaj   +1 more source

Adaptive mechanisms in no flow vs. low flow ischemia in equine jejunum epithelium: Different paths to the same destination

Frontiers in Veterinary Science, 2022
Intestinal ischemia reperfusion injury (IRI) is a frequent complication of equine colic. Several mechanisms may be involved in adaptation of the intestinal epithelium to IRI and might infer therapeutic potential, including hypoxia-inducible factor (HIF ...
Franziska Dengler, Felix Sternberg, Marei Grages, Sabine BR Kästner, Sabine BR Kästner, Nicole Verhaar   +5 more
doaj   +1 more source

Enlarged infarct volume and loss of BDNF mRNA induction following brain ischemia in mice lacking FGF-2 [PDF]

, 2006
FGF-2, a potent multifunctional and neurotrophic growth factor, is widely expressed in the brain and upregulated in cerebral ischemia. Previous studies have shown that intraventricularly or systemically administered FGF-2 reduces the size of cerebral ...
Kiprianova, Irina, Dono, Rosanna, Schindowski, Katharina, Krause, Sonja, Bohlen und Halbach, Oliver von, Schwaninger, Markus, Unsicker, Klaus   +6 more
core   +1 more source