Results 61 to 70 of about 588,404 (299)
Anticoagulation Treatment Response Among Phenotypic ESUS Clusters: Evidence From CASPR
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate treatment effect heterogeneity across phenotypic clusters of patients with cryptogenic embolic stroke using causal inference methods. Methods From a retrospective, multicenter cohort of patients with cryptogenic embolic stroke, we estimated the treatment effect of anticoagulation versus antiplatelet therapy in patients ...
Elena Badillo Goicoechea +53 more
wiley +1 more source
Maintaining oxygen delivery is crucial to prevent intestinal ischemia in critical ill patients.
PLoS ONE, 2021 BackgroundIntestinal ischemia is a common complication with obscure pathophysiology in critically ill patients. Since insufficient delivery of oxygen is discussed, we investigated the influence of oxygen delivery, hemoglobin, arterial oxygen saturation ...
Jochen J Schoettler +10 more
doaj +1 more source
Measurement of glutathione synthesis by isotope ratio mass spectrometry in systemic inflammation [PDF]
, 2010 During sepsis and critical illness, a systemic inflammatory response can significantly produce reactive oxygen and nitrogen species, which can damage host tissues.
Kimura, Y.
core
Glucagon‐Like Peptide‐1 Receptor Agonists in Multiple Sclerosis: A Topical Narrative Review
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT The glucagon‐like peptide‐1 (GLP‐1) receptor agonists (RAs) are a relatively new class of drugs that were initially approved by the US Food and Drug Administration to improve glycemic control in patients with type 2 diabetes mellitus and, subsequently, weight reduction in patients with obesity.
Audrey Y. Chang, Farrah J. Mateen
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective The aim of this study was to determine the differences in demographic, serologic, and clinical characteristics between male and female patients with systemic sclerosis (SSc) in an Australian cohort. Methods This was a retrospective observational study using data from the Australian Scleroderma Cohort Study.
Emily Lin +14 more
wiley +1 more source
Farnesoid X Receptor Activation Attenuates Intestinal Ischemia Reperfusion Injury in Rats.
PLoS ONE, 2017 IntroductionThe farnesoid X receptor (FXR) is abundantly expressed in the ileum, where it exerts an enteroprotective role as a key regulator of intestinal innate immunity and homeostasis, as shown in pre-clinical models of inflammatory bowel disease ...
Laurens J Ceulemans +11 more
doaj +1 more source
Effects of exercise preconditioning on intestinal ischemia-reperfusion injury [PDF]
, 2014 Background: To investigate the effects of exercise preconditioning on oxidative injury in the intestinal tissue of rats. Methods: Sixty male Wistar rats were randomly divided into six groups as sham (n = 10), ischemia-reperfusion (n = 10), exercise (n ...
Esen, H. +4 more
core +1 more source
Arthritis Care &Research, EarlyView.Objective The objective of this study was to evaluate the real‐world effectiveness and safety of secukinumab in patients with giant cell arteritis (GCA). Methods This multicenter retrospective study included patients with GCA who received secukinumab at 14 Italian centers with at least six months of follow‐up.
Luca Iorio +28 more
wiley +1 more source
Journal of Investigative Surgery, 2019 Purpose/Aim: Acute mesenteric ischemia is a syndrome characterized by sudden onset abdominal pain followed by intestinal necrosis. Morbidity and mortality increase with delayed diagnosis.
Mikail Cakir +10 more
doaj +1 more source
Bacterial translocation and mortality on rat model of intestinal ischemia and obstruction [PDF]
Acta Cirúrgica Brasileira, 2017 Purpose: To develop an experimental model of intestinal ischemia and obstruction followed by surgical resection of the damaged segment and reestablishment of intestinal transit, looking at bacterial translocation and survival.
Rafael Izar Domingues da Costa +4 more
doaj +1 more source