Results 71 to 80 of about 588,404 (299)

Somatostatin attenuates intestinal epithelial barrier injury during acute intestinal ischemia–reperfusion through Tollip/Myeloiddifferentiationfactor 88/Nuclear factor kappa-B signaling

, 2022
In the process of ischemia–reperfusion injury, intestinal ischemia and inflammation interweave, leading to tissue damage or necrosis. However, oxygen radicals and inflammatory mediators produced after reperfusion cause tissue damage again, resulting in ...
Ruo Shu (12088132), Yi Lei (766102), Yan Tian (298301), Yu Xu (52257), Xinfeng Zhang (1405234), Huayou Luo (7446911)   +5 more
core   +1 more source

Real‐World Safety of Concomitant Colchicine and Statin Therapy

Arthritis Care &Research, EarlyView.
Objective This study aimed to evaluate the risk of clinically meaningful muscle‐ and liver‐related outcomes associated with concomitant colchicine–statin therapy in a real‐world setting, and to determine whether concomitant therapy increases the incidence of toxicity compared with either agent alone.
Roni Meidan, Ranel Loutati, Dan Caspi, Ori Elkayam, Ran Abuhasira, Tali Eviatar   +5 more
wiley   +1 more source

Balloon occlusion of the aorta during cardiac arrest -a death blow to the intestines?

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Background The use of Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) in non-traumatic cardiac arrest may result in worsened intestinal ischaemia. What are the consequences?
Bjørn Hoftun Farbu, Jostein Brede
doaj   +1 more source

ROS‐Responsive Nanoparticle Delivery of Dexmedetomidine Protects the Gut Vascular Barrier After Intestinal Ischemia/Reperfusion via the HDAC‐H3K27ac‐TCF4 Axis [PDF]

Advanced science
A low dose of dexmedetomidine, delivered by ROS‐responsive nanoparticles, preferentially accumulates in the ischemic intestine and restores gut vascular barrier integrity after ischemia/reperfusion injury. This nanoparticle‐based strategy prevents bacterial translocation and liver damage without cardiorespiratory side effects, working through HDAC ...
Zhang H, Shen J, Zhang H, Gao S, Wang J, Wang Y, Li M, Liu Z, Zhang Y, Li Y, Zhang X.   +10 more
europepmc   +2 more sources

Polyphenol‐Inspired Materials for Agricultural Applications

Advanced Materials, EarlyView.
This review outlines the use of polyphenol‐inspired materials for sustainable agriculture, highlighting their molecular design, interfacial assembly, structure–property relationships, and prospects toward precision agriculture, climate resilience, ecosystem protection, and circular bioeconomy strategies.
Haofu Liu, Omid Mazaheri, Zhixing Lin, Tianzheng Wang, Jingqu Chen, Yuang Gu, Xia Liang, Deli Chen, Frank Caruso   +8 more
wiley   +1 more source

Laser Doppler Flowmetry in the Diagnosis of Intestinal Ischemia Severity

Russian Open Medical Journal
This systematic review evaluates the recent advancements over the past decade in the application of laser Doppler flowmetry (LDF) for measuring microcirculation and predicting outcomes in intestinal ischemia.
Gleb O. Mareev, Oleg V. Mareev, Sergey V. Kapralov, Grigory A. Klimenko, Tatyana Yu. Kalyuta   +4 more
doaj   +1 more source

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

Advanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin, Yimo Yan, Nikola Cesarovic, Simone Schuerle   +3 more
wiley   +1 more source

The Predictive Value of Mesenteric and Cerebral Tissue Oxygenation Measurements for Feeding Intolerance and Necrotizing Enterocolitis in Preterm

İstanbul Medical Journal
Introduction: Necrotizing enterocolitis (NEC) is a major cause of morbidity and mortality in preterm infants. Early detection of impaired intestinal perfusion may support preventive strategies.
Meltem Bor, Özkan İlhan
doaj   +1 more source

Calcitonin Gene-Related Peptide Downregulates Expression of Inducible Nitride Oxide Synthase and Caspase-3 after Intestinal Ischemia-Reperfusion Injury in Rats

Pediatrics and Neonatology, 2016
Various investigations have demonstrated that calcitonin gene-related peptide (CGRP) plays an important role in mediating ischemic preconditioning. CGRP has been shown to mimic the protective effects of ischemic preconditioning and mitigate ischemia ...
Chih-Cheng Luo, Chen-Sheng Huang, Yung-Ching Ming, Shih-Ming Chu, Hsun-Chin Chao   +4 more
doaj   +1 more source

Prolongation of the Intestinal Viability Using Oxygenated Perfluorocarbon in an Experimental Model of Acute Intestinal Ischemia [PDF]

, 2004
ObjectivesLiquid perfluorocarbons (PFCs) are well known for their capability to carry respiratory gases. The aim of this study was to evaluate the effectiveness of oxygenated F-Decalin on the intestinal viability, in an experimental model of acute ...
Pitoulias, G.A., D.K. Papadimitriou, E.N. Kaidoglou Anagnostopoulou, Papadimitriou, D.K., A.E. Alvanou Achparaki, Kotakidou, R.E., Kaidoglou Anagnostopoulou, E.N., Alvanou Achparaki, A.E., G.A. Pitoulias, R.E. Kotakidou   +9 more
core   +1 more source