Barrett’s Esophagus and Intestinal Metaplasia
Intestinal metaplasia refers to the replacement of the differentiated and mature normal mucosal epithelium outside the intestinal tract by the intestinal epithelium.
Lu Zhang+7 more
doaj +2 more sources
Rabeprazole suppressed gastric intestinal metaplasia through activation of GPX4-mediated ferroptosis [PDF]
BackgroundGastric intestinal metaplasia is a common pathological feature in patients with Helicobacter pylori (H. pylori) infection. Rabeprazole was widely used as the first-line regimen for H. pylori infectious treatment.
Jing Xie+15 more
doaj +2 more sources
Metaplasia intestinal especializada de esôfago distal na doença do refluxo gastroesofágico: prevalência e aspectos clínico-epidemiológicos Specialized intestinal metaplasia of distal esophagus in the gastroesophageal reflux disease: prevalence and clinical-demographic features [PDF]
RACIONAL: A metaplasia intestinal especializada pode ser classificada, de acordo com os achados endoscópicos e histológicos, em Barrett longo, Barrett curto e metaplasia intestinal da cárdia.
Leiber C. Caum+5 more
doaj +2 more sources
Pathogenesis and potential reversibility of intestinal metaplasia − a milestone in gastric carcinogenesis [PDF]
Non-cardia gastric cancer remains a major cause of cancer-related mortality worldwide, despite declining incidence rates in many industrialized countries.
Drnovsek Jan+3 more
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Association of high organochlorine pesticide serum levels with oxidative stress in intestinal metaplasia and gastric cancer [PDF]
It has been revealed that certain organochlorine pesticides may increase the risk of gastric cancer incidence among farm workers. This research aimed to assay levels of 7 different organochlorine pesticides in the serum of functional dyspepsia ...
Gholamreza Asadikaram+4 more
doaj +2 more sources
Barrett's esophagus and gastric intestinal metaplasia are molecularly similar precancerous lesions, with epithelial cells being mosaics of gastric and intestinal phenotypes and stromal cells showing features of cancer-associated fibroblasts.
K. Nowicki-Osuch+14 more
semanticscholar +1 more source
Alcohol consumption and the risk of gastric intestinal metaplasia in a U.S. Veterans population
Background Chronic alcohol use is a risk factor for non-cardia gastric adenocarcinoma. However, it is less well understood whether alcohol use is a risk factor for premalignant mucosal changes, namely gastric intestinal metaplasia.
Hudson M. Holmes+4 more
doaj +2 more sources
Objective To investigate the incidence of gastric cancer (GC) attributed to gastric intestinal metaplasia (IM), and validate the Operative Link on Gastric Intestinal Metaplasia (OLGIM) for targeted endoscopic surveillance in regions with low-intermediate
semanticscholar +1 more source
Oral and gastric microbiome in relation to gastric intestinal metaplasia
Evidence suggests that Helicobacter pylori plays a role in gastric cancer (GC) initiation. However, epidemiologic studies on the specific role of other bacteria in the development of GC are lacking.
Fen Wu+21 more
semanticscholar +1 more source
Background: Gastric intestinal metaplasia is known as a precursor of gastric cancer in the cascade of events from chronic gastritis to gastric adenocarcinoma.
Leila Mahmoudieh+4 more
doaj +1 more source