Barrett’s Esophagus and Intestinal Metaplasia [PDF]
Frontiers in Oncology, 2021 Intestinal metaplasia refers to the replacement of the differentiated and mature normal mucosal epithelium outside the intestinal tract by the intestinal epithelium.
Lu Zhang +7 more
doaj +4 more sources
Pathogenesis and potential reversibility of intestinal metaplasia − a milestone in gastric carcinogenesis [PDF]
Radiology and OncologyNon-cardia gastric cancer remains a major cause of cancer-related mortality worldwide, despite declining incidence rates in many industrialized countries.
Drnovsek Jan +3 more
doaj +3 more sources
Severity of gastric intestinal metaplasia predicts the risk of gastric cancer: a prospective multicentre cohort study (GCEP) [PDF]
Gut, 2021 Objective To investigate the incidence of gastric cancer (GC) attributed to gastric intestinal metaplasia (IM), and validate the Operative Link on Gastric Intestinal Metaplasia (OLGIM) for targeted endoscopic surveillance in regions with low-intermediate
Jonathan Lee +27 more
openalex +2 more sources
Journal of Pathology of Nepal, 2020 Background: Gastric intestinal metaplasia is seen chronic gastritis associated with Helicobacter pylori. The objective of this study was to determine the prevalence of subtypes of intestinal metaplasia and presence of Helicobacter pylori infection ...
Sanat Chalise +2 more
doaj +3 more sources
TFF3 initiates gastric intestinal metaplasia by activating JAK2 and STAT3 under high salt conditions [PDF]
Scientific ReportsThe mechanism underlying the role of trefoil factor family 3 (TFF3) in intestinal metaplasia remains unclear. This study reveals the molecular mechanism by which TFF3, in the process of gastric mucosal epithelial cell intestinal metaplasia (IM) induced ...
Yanhong Wang +10 more
doaj +2 more sources
Gastroenterology, 2023 Gastric intestinal metaplasia (GIM), which denotes conversion of gastric mucosa into an intestinal phenotype, can occur in all regions of the stomach, including cardiac, fundic, and pyloric mucosa. Since the earliest description of GIM, its association with gastric cancer of the differentiated (intestinal) type has been a well-recognized concern.
Sugano, Kentaro +2 more
openaire +2 more sources
Rabeprazole suppressed gastric intestinal metaplasia through activation of GPX4-mediated ferroptosis [PDF]
Frontiers in PharmacologyBackgroundGastric intestinal metaplasia is a common pathological feature in patients with Helicobacter pylori (H. pylori) infection. Rabeprazole was widely used as the first-line regimen for H. pylori infectious treatment.
Jing Xie +15 more
doaj +2 more sources
Adenocarcinoma risk in gastric atrophy and intestinal metaplasia: a systematic review [PDF]
BMC Gastroenterology, 2017 BackgroundGastric cancer (GC) has a poor prognosis with wide variation in survival rates across the world. Several studies have shown premalignant lesions gastric atrophy (GA) and intestinal metaplasia (IM) influence gastric cancer risk.
Andrew D. Spence +6 more
openalex +2 more sources
Oral and gastric microbiome in relation to gastric intestinal metaplasia [PDF]
International Journal of Cancer, 2021 Fen Wu +21 more
openalex +2 more sources
Association of high organochlorine pesticide serum levels with oxidative stress in intestinal metaplasia and gastric cancer [PDF]
HeliyonIt has been revealed that certain organochlorine pesticides may increase the risk of gastric cancer incidence among farm workers. This research aimed to assay levels of 7 different organochlorine pesticides in the serum of functional dyspepsia ...
Gholamreza Asadikaram +4 more
doaj +2 more sources