Results 91 to 100 of about 24,724 (228)

Expression profile of mucins (MUC2, MUC5AC and MUC6) in Helicobacter pylori infected pre-neoplastic and neoplastic human gastric epithelium

Molecular Cancer, 2006
Background Helicobacter pylori (H. pylori) causes gastritis and intestinal metaplasia (IM) that may evolve to gastric carcinoma. The objective of this study was to compare the profile of mucins in the progressive stages of H.
Reis Celso A, Devaraj Niranjali, Jayanthi Venkataraman, Babu Subramani, Devaraj Halagowder   +4 more
doaj   +1 more source

Optimization of the Nonclinical Biological Evaluation of Medical Devices Using Toxicologic Pathology Best Practices

Advanced Healthcare Materials, Volume 15, Issue 3, 19 January 2026.
Nonclinical evaluation of biological responses to implanted medical devices and combination products in animals is required to predict possible outcomes and risks in patients. This paper describes globally accepted pathology “best practices” that 1) effectively address ISO standards and current regulatory guidance for medical device development and 2 ...
Kathleen A. Funk, JoAnn C. L. Schuh, Brad Bolon, Valerie S. Thomas, Jeffrey I. Everitt, Abraham Nyska, Jaime Paulin   +6 more
wiley   +1 more source

DKK3 Initially Preserves Acinar Integrity Through MEK‐Fos Signaling, but Later Switches to an Oncogenic Role in Pancreatic Cancer

Advanced Science, Volume 13, Issue 3, 14 January 2026.
In pancreatic cancer, the protein DKK3 is found to play a complex role: it initially slows early tumor growth but later promotes tumor aggressiveness. DKK3 expression evolves during progression and drives cancer severity by orchestrating cellular and molecular signaling pathways.
Dharini Srinivasan, Elodie Roger, Lukas Perkhofer, Eleni Zimmer, Thomas F.E. Barth, Julia P. Mosler, Anna Härle, Stephanie E. Weissinger, Nadine T. Gaisa, Peter Möller, Nico Fischer, Chantal Allgöwer, J.‐Matthias Löhr, Dirk Grimm, Thomas Seufferlein, Stefan Liebau, Ninel Azoitei, Michael K. Melzer, Frank Arnold, Johann Gout, Alexander Kleger   +20 more
wiley   +1 more source

Mature Cystic Teratoma of the Right Adrenal Gland in a Pediatric Patient: A Case Report

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Adrenal teratomas are rare neoplasms, most often benign but with potential for malignant transformation, particularly in the pediatric population. A seven‐year‐old girl from kawasoti, Nepal, presented with intermittent right‐sided abdominal pain for 2 months, initially attributed to dietary factors such as junk food intake.
Amit Gautam, Pukar Adhikari, Shishir Bhandari, Jabir Ahamad Miya, Nikesh Tiwari   +4 more
wiley   +1 more source

Immunoinformatics‐Based Multi‐Epitope Vaccine Targeting Helicobacter Pylori

Cancer Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Background The rising global incidence of Helicobacter pylori‐related diseases, particularly gastric cancer, underscores the urgent need for effective preventive vaccines, motivating the exploration of innovative immunoinformatic strategies to address this public health challenge.
Aytak Vahdat Khajeh Pasha, Mohammad Esfandiyari, Alireza Parnian, Mohammad Mahboubi‐Rabbani, Maryam Bayanati   +4 more
wiley   +1 more source

Integrated Single Cell Spatial Analysis Reveals Dysregulated Basal Progenitor Cells in Ulcerative Colitis Pathogenesis: A Multi Omics Study

Health Science Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Background and Aims Ulcerative colitis (UC), a chronic inflammatory bowel disease, causes persistent mucosal inflammation and epithelial dysfunction. Basal progenitor cells (BPCs), critical for intestinal regeneration and mucosal repair, exhibit altered behavior in UC.
Xiaopeng Chen, Chuiguo Huang, Zhuofeng Wen, Weixuan Liang, Haobin Zhou, Zhiyi Zhou, Songan Li, Jianyang Guo, Naijun Yuan, Wanzhe Liao   +9 more
wiley   +1 more source

Incomplete sulphomucin-secreting intestinal metaplasia for gastric cancer. Preliminary data from a prospective study from three centres. [PDF]

, 1985
M I Filipe, F Potet, Wladimir V. Bogomoletz, Paul A. Dawson, Bettina Fabiani, P Chauveinc, A Fenzy, Brian Gazzard, D Goldfain, R Zeegen   +9 more
openalex   +1 more source

Oral and gastric microbiome in relation to gastric intestinal metaplasia [PDF]

, 2021
Fen Wu, Liying Yang, Yuhan Hao, Boyan Zhou, Jiyuan Hu, Yaohua Yang, Sukhleen Bedi, Navin Ganesh Sanichar, Charley Cheng, Sophie Stevens, Wenche Tseng, Wenzhi Tseng, Mengkao Tseng, Fritz François, Anzalee Khan, Yihong Li, Martin J. Blaser, Xiao‐Ou Shu, Jirong Long, Huilin Li, Zhiheng Pei, Yu Chen   +21 more
openalex   +1 more source

Evaluation of Total Serum IgE Level and Associated Factors in Asthmatic Patients at the University of Gondar Hospital, Northwest Ethiopia: A Comparative Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Background and Aims Asthma is a chronic respiratory disorder with both genetic and environmental underlying risk factors. Allergic asthma, the most prevalent kind, is mostly ascribed to aberrant T helper type 2 (Th2) inflammation and is brought on by allergens.
Ayenew Assefa, Tadelo Wondmagegn, Markos Negash   +2 more
wiley   +1 more source

A Perspective on Software Intelligence for Autonomous Transformations in Biomedical Data and Knowledge

Learning Health Systems, Volume 10, Issue 1, January 2026.
ABSTRACT Introduction Persistent knowledge is essential for propagating the learning health system (LHS) cycle. Integral to the cycle are iterative transformations of data into knowledge. However, human efforts to undertake these transformations are increasingly challenged when dealing with larger data scales and complexities.
Vivek Navale
wiley   +1 more source