Results 81 to 90 of about 401,397 (233)

Traditional serrated adenoma of the colorectum: Evolving concepts in histological classification and terminology

Histopathology, EarlyView.
The definition of the colorectal traditional serrated adenoma (TSA) has evolved to recognize a broader morphological spectrum, including classical, flat and mixed lesions reflecting early development and neoplastic progression. Updated WHO classification highlights the need for consistent terminology to improve recognition and to distinguish TSA from ...
Christophe Rosty, Maurice B. Loughrey, Taiki Hashimoto, Markus Mäkinen, Rish K. Pai, Shigeki Sekine, Rhonda K. Yantiss, Iris D. Nagtegaal   +7 more
wiley   +1 more source

Apoptosis and proliferation in Helicobacter pylori-associated gastric intestinal metaplasia

, 2001
Background: Imbalance between apoptosis and proliferation may be one of the mechanisms underlying H. pylori associated gastric carcinogenesis. Aim: To examine the cell kinetics of gastric intestinal metaplasia and the effect of H.
Go, MYY, Chan, FKL, Ma, PK, Yu, J, Leung, WK, To, KF, Sung, JJY   +6 more
core   +1 more source

Comprehensive and reproducible grading of the Updated Sydney System in gastric biopsies using artificial intelligence: multi‐pathologist validation and a reader study

Histopathology, EarlyView.
SydneyMTL is an interpretable multi‐task model providing four‐level grading for the five Sydney System attributes. By significantly improving diagnostic concordance and reducing reading time, it offers a robust clinical tool to alleviate pathologist workloads and standardize routine gastric biopsy screening.
Ho Heon Kim, Won Chan Jeong, Yuri Hwang, Gisu Hwang, Kyungeun Kim, Young Sin Ko   +5 more
wiley   +1 more source

Born early, age fast: Consequences of premature birth on chronic disease and accelerated ageing

The Journal of Physiology, EarlyView.
Abstract figure legend ELGANs are exposed to several postnatal pro‐oxidant stressors, including ambient and supplemental oxygen, mechanical ventilation, infections, hyperalimentation, excessive glucocorticoids and intermittent hypoxia. Since endogenous antioxidant defences are underdeveloped, this imbalance promotes oxidative stress and inflammation ...
Estelle B. Gauda, Julijana Ivanovska, Dwayne Mascarenhas, Jeffrey Antwi, Atefeh Mohammadi, Bonny Jasani   +5 more
wiley   +1 more source

The multicellular environment of the re‐entrant circuit in post‐myocardial infarction ventricular tachycardia: Beyond fibrosis

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the temporal evolution of the post‐myocardial infarction substrate leading to ventricular tachycardia. Acute ischaemic injury initiates metabolic and electrophysiological disruption, followed by progressive inflammatory, fibrotic and structural remodelling within the infarct border zone.
Mohammed Obeidat, Jaffar Al‐Sheikhli, Andrew M. Blanks, Joseph Mayer, Nicolas Lellouche, Tarvinder Dhanjal, Christopher O'Shea   +6 more
wiley   +1 more source

Histological Helicobacter pylori Density Might Not be Associated With the Severity of Neutrophilic Inflammatory Activity

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Background While the Updated Sydney System classifies Helicobacter pylori density together with inflammatory scores, the clinical relevance of bacterial load remains uncertain. This study aimed to assess the association between histological H. pylori density and the severity of gastric inflammatory activity.
Guochun Lou, Zhengchen Yu, YongWei Wang, BingQiang Xu, Qin Du, Jun Ye   +5 more
wiley   +1 more source

Evaluation of Computer‐aided Detection for Identifying Missed Gastric Cancer After Endoscopic Submucosal Dissection

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Objectives Computer‐aided detection (CADe) using deep learning is promising for reducing missed gastric cancers (MGCs) and supporting physicians in double‐checking endoscopic images. We aimed to evaluate the CADe efficacy for MGCs after endoscopic submucosal dissection (ESD).
Tatsunori Minamide, Tomonori Sato, Seiichiro Sakaguchi, Noboru Kawata, Yuki Maeda, Masao Yoshida, Yoichi Yamamoto, Taishi Okumura, Tetsuya Suwa, Hiroshi Ashizawa, Kohei Shigeta, Haruka Nakamura, Akifumi Notsu, Toshio Uraoka, Hiroyuki Ono   +14 more
wiley   +1 more source

White Globe Appearance Is an Endoscopic Predictor of Metachronous Multiple Gastric Cancers

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Objectives White globe appearance (WGA) is a small white lesion with a globular shape identified during magnifying endoscopy with narrow‐band imaging. However, the association between WGA and metachronous gastric cancer remains unclear. Methods This study involved patients who underwent endoscopic submucosal dissection (ESD) for first‐episode ...
Manami Utsunomiya, Hiroyoshi Nakanishi, Naohiro Yoshida, Saori Miyajima, Azusa Kawasaki, Shigenori Wakita, Yosuke Kito, Kunihiro Tsuji, Haruhiko Shugo, Shigetsugu Tsuji, Sho Tsuyama, Kazuyoshi Katayanagi, Hiroshi Minato, Hisashi Doyama   +13 more
wiley   +1 more source

Early Gastric Cancer Detected During 15‐year Surveillance After Ménétrier Disease Remission and Successfully Treated With Endoscopic Submucosal Dissection: A Case Report

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Ménétrier disease (MD) was diagnosed based on hypoalbuminemia and giant gastric folds extending from the body to the fundus in a woman in her 70s. A serum anti‐Helicobacter pylori antibody test and urea breath test yielded negative results.
Takaaki Shamoto, Hideko Yamamoto, Takehito Naito, Masahiro Yamada, Hirotaka Suzuki, Emiko Hida, Takafumi Yamamoto, Yoshifumi Arai, Hiroshi Matsubara   +8 more
wiley   +1 more source

Third Space Endoscopic Therapies for Benign Motility Disorders: A Narrative Review

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Objectives To review the evidence base, evolution, outcomes, adverse events (AEs), and management for third‐space endoscopy (TSE) procedures for management of benign motility disorders. Methods This review examines TSE procedures for motility disorders, reviewing the current available techniques, success, outcomes, and long‐term outcomes from ...
Sanjana Bhagwat, Amol Bapaye
wiley   +1 more source