Results 91 to 100 of about 401,397 (233)

Gastric Epithelial Dysplasia and Sulphomucin-Type Intestinal Metaplasia

, 1983
The HID-AB histologic staining technique, which distinguishes sulphomucin from sialomucin types of intestinal metaplasia, was employed in endoscopic gastric mucosal biopsies to evaluate their frequency of association with epithelial dysplasia ...
Francesco Di Mario, Massimo Rugge, Fabrizio Cardin, Roberto Farini, Remo Naccarato, Carla Arslan Pagnini   +5 more
core   +1 more source

Efficacy and Safety of Elagolix Versus Dienogest for Treatment of Moderate‐to‐Severe Endometriosis Pain: A Phase III, Multicentric, Double‐Blind, Active‐Controlled, Non‐Inferiority Study

BJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 11, Page 2025-2034, October 2026.
ABSTRACT Objective To compare the efficacy, safety and tolerability of elagolix with dienogest in women with moderate‐to‐severe endometriosis‐associated pain. Design A multicentre, double‐blind, double‐dummy, randomised, parallel‐group, active‐controlled, non‐inferiority phase III study. Setting Nineteen clinical centres across India.
Sneha Bhoir, Jaldhara Patel, Tushar Palve, Mrinal Kanti Dash, Sweety Saigal, Gourisankar Kamilya, Shalini Srivastava, Kartikbhai Savalia, Tanusree Gupta, Deepa Choudhary, Manohar Rangaswamy, Vidya V Bhatt, Neena Gupta, Malathi Ponnuru, Parul Shah, Apurva Shetty, Shruti Saha, Reshma Quadros, Sucheta Pandit, Dipak Patil, Piyush Patel, Pravin Ghadge, Lalit Lakhwani, Suyog Mehta, Sadhana Joglekar   +24 more
wiley   +1 more source

A Cell Marker Atlas to Distinguish Metaplastic Transitions in Human Esophagus and Stomach

Cellular and Molecular Gastroenterology and Hepatology
Metaplasia is an adaptative response to injury and inflammation and can be a precursor to dysplasia and cancer. Metaplasia in the esophagus, termed Barrett’s esophagus, is the replacement of the stratified squamous epithelium by glandular tissue ...
Karen J. Dunbar, Su-Hyung Lee, Yoonkyung Won, Emily M. Esquea, Jeong Yun Yang, Daniel O. Kechele, Sandra Ryeom, Julian A. Abrams, Frank D. McKeon, James M. Wells, Micheal Quante, Eunyoung Choi, Jianwen Que, Timothy C. Wang, Anil K. Rustgi, James R. Goldenring   +15 more
doaj   +1 more source

IL‐22Rα1 restrains pancreatic injury independently of its C‐terminal STAT3‐amplifying domain

Journal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.
IL‐22R, and to a lesser extent IL‐22, are key drivers of protection in acute pancreatitis. Although the C‐terminal domain of IL‐22R enhances STAT3 activation in the pancreas, it is not required for disease protection. Classical IL‐22R signaling alone is sufficient to control inflammation and promote pancreatic recovery.
Léna Puigdevall, Clara Stewardson, Lysa Dhulst, Emilie Hendrickx, Laure Dumoutier   +4 more
wiley   +1 more source

Bronchiectasis as an Underrecognized Extraintestinal Manifestation of Inflammatory Bowel Disease

JCC Plus, Volume 1, Issue 5, September 2026.
ABSTRACT Introduction Inflammatory bowel diseases (IBD) are chronic inflammatory diseases of the gastrointestinal tract, often presenting with extraintestinal manifestations (EIMs). The most prevalent pulmonary EIM is IBD‐associated bronchiectasis (IBD‐BE), which is often overlooked.
Lynn te Slaa, Josje Altenburg, Mark Löwenberg   +2 more
wiley   +1 more source

Current Helicobacter pylori Diagnostics: Established Methods, Resistance Testing, and Emerging Approaches

JGH Open, Volume 10, Issue 9, September 2026.
ABSTRACT Aims Accurate diagnosis of Helicobacter pylori infection is required to detect active infection, confirm eradication, assess gastric pathology when indicated, and obtain antimicrobial resistance information that may guide treatment. This review evaluates the clinical roles, limitations, and implementation maturity of established, molecular ...
Tianhua Tang, Erwin A. Paz, Kan Yu, Khui Hung Lee, Chin Yen Tay, Jingjing Wang, Barry James Marshall, Linli Hu, Wanting Fu, Ziyao Yang   +9 more
wiley   +1 more source

Knowledge gaps in tubular gut tumours: a critical appraisal of the 6th edition of the World Health Organization classification of tumours

The Journal of Pathology, Volume 270, Issue 1, Page 4-22, September 2026.
Abstract Gastrointestinal cancer is a global health problem. In the new 6th edition of the World Health Organization Classification of Tumours (WCT) of the Digestive System, updated evidence and guidance is provided for the aetiology, pathogenesis, diagnosis, classification, grading, staging and prognosis of these tumours.
Iris D Nagtegaal, Elizabeth A Montgomery, Alexandros D Polydorides, Anthony J Gill, Motohiro Kojima, Mark J Arends   +5 more
wiley   +1 more source

Small adenocarcinomas of the esophagogastric junction: association with intestinal metaplasia and dysplasia

, 2002
OBJECTIVES: Intestinal metaplasia in Barrett’s esophagus predisposes to esophageal adenocarcinoma. Intestinal metaplasia of the cardia is a common finding in persons without cancer. Many adenocarcinomas of the esophagogastric junction are large enough to
Cameron, Alan J, Souto, Enrico O, Smyrk, Thomas C   +2 more
core   +1 more source

When Fat Goes Astray: Your Liver and Pancreas Get Into Trouble

Portal Hypertension &Cirrhosis, Volume 5, Issue 3, Page 269-282, September 2026.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) and intrapancreatic fat deposition (IPFD) are both common manifestations of ectopic fat accumulation. Although they share multiple risk factors, they also show notable differences in pathological features, standardization of diagnosis, and research maturity.
Yuying Chen, Li Ding, Shan Zhao, Weihong Wang, Jing Zhong, Qiang Yan   +5 more
wiley   +1 more source

Dedicated Endoscopy for Barrett's Oesophagus With Higher Dysplasia Yield May Reduce Seattle Protocol Biopsies: Results From UK Multicentre Study

United European Gastroenterology Journal, Volume 14, Issue 7, September 2026.
ABSTRACT Background Dedicated service for Barrett's oesophagus (BO) surveillance may be more effective than conventional service, according to some single centre studies. Objective To determine whether the surveillance of BO through a dedicated service can improve key performance indicators (KPIs), and dysplasia detection rate (DDR) compared with ...
Champika Gamakaranage, James Britton, Elizabeth Ratcliffe, Neeraj Prasad, Richard Keld, Mark Murgatroyd, Shanmugasundaram Balakrishnan, Nazar Aslam, Vinay Sehgal, Jenni Marsh, Daniel Plant, Matthew Johnston, Stefanos Kateroglou, Jake Baker, Hannah Morgan, Claudia Cipriano, Anjan Dhar, Shaheen Hamdy, John McLaughlin, Yeng Ang, on behalf ofDEBO group   +20 more
wiley   +1 more source