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Gastric Cancer Risk in Patients with Intestinal Metaplasia: Long-Term Outcomes from a Large Single-Center Cohort in Türkiye. [PDF]

open access: goldJ Clin Med
Tomar VB   +10 more
europepmc   +3 more sources

Comment: Gastric intestinal metaplasia and smoking Comentario: Metaplasia intestinal gástrica y tabaco

open access: yesGaceta Sanitaria, 2008
Although the pathogenesis of intestinal metaplasia remains unknown1, it is well recognized that chronic gastritis and intestinal metaplasia are precursor conditions of gastric cancer.
Carlos A. González
doaj   +4 more sources

CDX2-induced intestinal metaplasia in human gastric organoids derived from induced pluripotent stem cells

open access: yesiScience, 2022
Summary: Intestinal metaplasia is related to gastric carcinogenesis. Previous studies have suggested the important role of CDX2 in intestinal metaplasia, and several reports have shown that the overexpression of CDX2 in mouse gastric mucosa caused ...
Takahiro Koide   +4 more
doaj   +1 more source

Alcohol consumption and the risk of gastric intestinal metaplasia in a U.S. Veterans population

open access: yesPLoS ONE, 2021
Background Chronic alcohol use is a risk factor for non-cardia gastric adenocarcinoma. However, it is less well understood whether alcohol use is a risk factor for premalignant mucosal changes, namely gastric intestinal metaplasia.
Hudson M. Holmes   +4 more
doaj   +2 more sources

Single-Cell RNA Sequencing Unifies Developmental Programs of Esophageal and Gastric Intestinal Metaplasia

open access: yesCancer Discovery, 2023
Barrett's esophagus and gastric intestinal metaplasia are molecularly similar precancerous lesions, with epithelial cells being mosaics of gastric and intestinal phenotypes and stromal cells showing features of cancer-associated fibroblasts.
K. Nowicki-Osuch   +14 more
semanticscholar   +1 more source

Helicobacter pylori promotes gastric intestinal metaplasia through activation of IRF3-mediated kynurenine pathway

open access: yesCell Communication and Signaling, 2023
Background Metabolic reprogramming is a critical event for cell fate and function, making it an attractive target for clinical therapy. The function of metabolic reprogramming in Helicobacter pylori ( H.
Xinhua Liang   +10 more
semanticscholar   +1 more source

The subtleties of intestinal metaplasia [PDF]

open access: yesGut, 2001
See article on page 73 Even if its incidence has decreased due to the influence of environmental and nutritional factors, gastric carcinoma remains a major concern because of its very poor prognosis. Screening for precancerous conditions, including intestinal metaplasia, is one method of improving the prognosis of gastric carcinoma. Nevertheless, the
R, Rouzier, S, Robine
openaire   +2 more sources

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