Results 11 to 20 of about 22,347 (209)

Rabeprazole suppressed gastric intestinal metaplasia through activation of GPX4-mediated ferroptosis [PDF]

Frontiers in Pharmacology
BackgroundGastric intestinal metaplasia is a common pathological feature in patients with Helicobacter pylori (H. pylori) infection. Rabeprazole was widely used as the first-line regimen for H. pylori infectious treatment.
Jing Xie, Xinhua Liang, Fangfang Xie, Canxin Huang, Zijun Lin, Shuping Xie, Fangying Yang, Fengfeng Zheng, Lanlan Geng, Lanlan Geng, Wanfu Xu, Wanfu Xu, Sitang Gong, Sitang Gong, Li Xiang, Li Xiang   +15 more
doaj   +2 more sources

Pathogenesis and potential reversibility of intestinal metaplasia − a milestone in gastric carcinogenesis [PDF]

Radiology and Oncology
Non-cardia gastric cancer remains a major cause of cancer-related mortality worldwide, despite declining incidence rates in many industrialized countries.
Drnovsek Jan, Homan Matjaz, Zidar Nina, Smid Lojze M   +3 more
doaj   +2 more sources

Association of high organochlorine pesticide serum levels with oxidative stress in intestinal metaplasia and gastric cancer [PDF]

Heliyon
It has been revealed that certain organochlorine pesticides may increase the risk of gastric cancer incidence among farm workers. This research aimed to assay levels of 7 different organochlorine pesticides in the serum of functional dyspepsia ...
Gholamreza Asadikaram, Mohammad Reza Ashrafi, Sodaif Darvish Moghaddam, Moslem Abolhassani, Fatemeh Bagheri   +4 more
doaj   +2 more sources

Alcohol consumption and the risk of gastric intestinal metaplasia in a U.S. Veterans population

PLoS ONE, 2021
Background Chronic alcohol use is a risk factor for non-cardia gastric adenocarcinoma. However, it is less well understood whether alcohol use is a risk factor for premalignant mucosal changes, namely gastric intestinal metaplasia.
Hudson M. Holmes, Andre G. Jove, Mimi C. Tan, Hashem B. El-Serag, Aaron P. Thrift   +4 more
doaj   +2 more sources

Barrett’s Esophagus and Intestinal Metaplasia

Frontiers in Oncology, 2021
Intestinal metaplasia refers to the replacement of the differentiated and mature normal mucosal epithelium outside the intestinal tract by the intestinal epithelium.
Lu Zhang, Binyu Sun, Xi Zhou, QiongQiong Wei, Sicheng Liang, Gang Luo, Tao Li, Muhan Lü   +7 more
doaj   +1 more source

Identification of serum microRNAs as potential diagnostic biomarkers for detecting precancerous lesions of gastric cancer

Annals of Gastroenterological Surgery, Volume 7, Issue 1, Page 63-70, January 2023., 2023
We found that microRNA‐196b‐5p was significantly upregulated in precancerous lesions and that combining it with other microRNAs increased the accuracy of detection. Since endoscopy is associated with risk, the identification of high‐risk groups for gastric cancer is expected to make it possible to clearly identify groups that should undergo endoscopy ...
Hajime Otsu, Sho Nambara, Qingjiang Hu, Yuichi Hisamatsu, Takeo Toshima, Kazuki Takeishi, Yusuke Yonemura, Takaaki Masuda, Eiji Oki, Koshi Mimori   +9 more
wiley   +1 more source

Analysis of Probable Risk Factors of Gastric Intestinal Metaplasia in Patients Referred to the Gastroenterology Clinic with Dyspepsia

Asian Pacific Journal of Cancer Biology, 2023
Background: Gastric intestinal metaplasia is known as a precursor of gastric cancer in the cascade of events from chronic gastritis to gastric adenocarcinoma.
Leila Mahmoudieh, Naghmeh Salarieh, Mojgan Forootan, Somayeh Fatemizadeh, Pardis Ketabi Moghadam   +4 more
doaj   +1 more source

Prevalence of subtypes of gastric intestinal metaplasia and its relationship with Helicobacter pylori infection

Journal of Pathology of Nepal, 2020
Background: Gastric intestinal metaplasia is seen chronic gastritis associated with Helicobacter pylori. The objective of this study was to determine the prevalence of subtypes of intestinal metaplasia and presence of Helicobacter pylori infection ...
Sanat Chalise, Roshan Ghimire, Sailesh B. Pradhan   +2 more
doaj   +1 more source

Lipid metabolism in pancreatic cancer: emerging roles and potential targets

Cancer Communications, Volume 42, Issue 12, Page 1234-1256, December 2022., 2022
Abstract Pancreatic cancer is one of the most serious health issues in developed and developing countries, with a 5‐year overall survival rate currently <9%. Patients typically present with advanced disease due to vague symptoms or lack of screening for early cancer detection.
Xinpeng Yin, Ruiyuan Xu, Jianlu Song, Rexiati Ruze, Yuan Chen, Chengcheng Wang, Qiang Xu   +6 more
wiley   +1 more source

Shared features of metaplasia and the development of adenocarcinoma in the stomach and esophagus

Frontiers in Cell and Developmental Biology, 2023
Introduction: Plasticity is an inherent property of the normal gastrointestinal tract allowing for appropriate response to injury and healing. However, the aberrancy of adaptable responses is also beginning to be recognized as a driver during cancer ...
Yongji Zeng, Qing K. Li, Sujayita Roy, Jason C. Mills, Jason C. Mills, Ramon U. Jin   +5 more
doaj   +1 more source