Results 51 to 60 of about 321,806 (308)

The role of mucosal immunity in the pathogenesis of necrotizing enterocolitis [PDF]

, 2017
Necrotizing enterocolitis (NEC) is the most devastating gastrointestinal disease of prematurity. Although the precise cause is not well understood, the main risk factors thought to contribute to NEC include prematurity, formula feeding, and bacterial ...
Bolock, Alexa M, Good, Misty, Hodzic, Zerina   +2 more
core   +2 more sources

Intestinal Microbiota Metabolism and Atherosclerosis

Chinese Medical Journal, 2015
This review aimed to summarize the relationship between intestinal microbiota metabolism and cardiovascular disease (CVD) and to propose a novel CVD therapeutic target.This study was based on data obtained from PubMed and EMBASE up to June 30, 2015.
Tian-Xing Liu, Hai-Tao Niu, Shu-Yang Zhang   +2 more
openaire   +3 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Ammonia exposure induced intestinal inflammation injury mediated by intestinal microbiota in broiler chickens via TLR4/TNF-α signaling pathway

Ecotoxicology and Environmental Safety, 2021
Ammonia is a known environmental pollutant that causes injury to the intestine. Growing evidence suggests that intestinal microbiota dysbiosis involves in the development of intestinal injury under environmental pollution. However, the specific mechanism
Ying Zhou, Minhong Zhang, Xin Zhao, Jinghai Feng   +3 more
doaj   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

[Intestinal microbiota].

Bulletin de l'Academie nationale de medecine, 2016
The human body normally lives in symbiosis with a considerable microscopic environment present on all interfaces with the external environment; it hosts ten times more microbes (microbiota) that it has somatic or germ cells, representing a gene diversity (microbiome) 100-150 times higher than the human genome. These germs are located mainly in the gut,
Patrice, Debré, Jean-Yves, Le Gall
openaire   +3 more sources

Murine fecal microbiota transplantation lowers gastrointestinal pathogen loads and dampens pro-inflammatory immune responses in Campylobacter jejuni infected secondary abiotic mice [PDF]

, 2019
Conventional mice are protected from Campylobacter jejuni infection by the murine host-specific gut microbiota composition. We here addressed whether peroral fecal microbiota transplantation (FMT) might be an antibiotics-independent option to lower even ...
Bereswill, Stefan, Heimesaat, Markus M., Mrazek, Katharina   +2 more
core   +1 more source

The globalization of intestinal microbiota [PDF]

European Journal of Clinical Microbiology & Infectious Diseases, 2010
Many microorganisms reside in human mucosa, specifically in the gut. There are many sources of the microorganisms that colonize our gut, and these sources are mainly environmental. Indeed, food is a major source of bacteria and viruses. Food also modifies the equilibrium of microorganisms in our gut, with vegetables favoring a wider diversity.
openaire   +2 more sources

Dual‐Layer Living Hydrogel Enables On‐Demand Delivery of Phages and Probiotics for Synergistic Wound Infection Therapy

Advanced Functional Materials, EarlyView.
A dual‐layer living hydrogel, ProΦGel, integrates bacteriophages and probiotics for synergistic wound infection therapy. The outer gelatin‐based matrix releases phages on demand in response to P. aeruginosa infections, while inner alginate beads sustain probiotic delivery.
Siyuan Tao, Darine D'Adam, Anna Hu, Sixuan Zhang, Josua Roduner, Katharina Maniura‐Weber, Qun Ren   +6 more
wiley   +1 more source

The SERPINB4 gene mutation identified in twin patients with Crohn’s disease impaires the intestinal epithelial cell functions

Scientific Reports
Crohn’s disease (CD) is a chronic inflammatory autoimmune disease of unknown etiology. To identify new targets related to the initiation of CD, we screened a pair of twins with CD, which is a rare phenomenon in the Chinese population, for genetic ...
Xiao-Mei Ouyang, Jun-Hui Lin, Ying Lin, Xian-Ling Zhao, Ya‐Ni Huo, Lai-Ying Liang, Yong-Dong Huang, Gui-Jing Xie, Peng Mi, Zhen-Yu Ye, Bayasi Guleng   +10 more
doaj   +1 more source