Results 141 to 150 of about 330,676 (367)

Avaliação da eficácia do colostro bovino hiperimune na infecção experimental de roedores com Cryptosporidium parvum

open access: yesBrazilian Journal of Veterinary Research and Animal Science, 2003
O colostro bovino hiperimune contém alta concentração de anticorpos anti- Cryptosporidium parvum. Este produto é considerado como uma das estratégias terapêuticas promissoras no controle da criptosporidiose intestinal em humanos.
Vicente José Salles de Abreu   +5 more
doaj   +1 more source

Mechanisms of Baicalin Alleviates Intestinal Inflammation: Role of M1 Macrophage Polarization and Lactobacillus amylovorus

open access: yesAdvanced Science, EarlyView.
Baicalin alleviates E. coli‐induced intestinal inflammation through dual mechanisms: direct inhibition of the TLR4/IRF/STAT signaling pathway to modulate macrophage polarization and antigen presentation, thereby regulating Th17/Treg cell differentiation; and microbiota‐mediated indirect effects via increasing Lactobacillus amylovorus abundance and ...
Shunfen Zhang   +10 more
wiley   +1 more source

Targeting PTBP3‐Mediated Alternative Splicing of COX11 Induces Cuproptosis for Inhibiting Gastric Cancer Peritoneal Metastasis

open access: yesAdvanced Science, EarlyView.
The splicing factor PTBP3 promotes COX11 exon skipping, allowing gastric cancer organoids to evade cuproptosis. Antisense oligonucleotide drugs targeting PTBP3‐mediated COX11 alternative splicing, in combination with copper ionophores, promote cuproptosis in organoids, thereby providing a therapeutic approach for gastric cancer peritoneal metastasis ...
Yajing Zhou   +11 more
wiley   +1 more source

Multi‐omics analyses reveal the interaction between colonic microbiota and host in Min and Yorkshire pigs

open access: yesAnimal Research and One Health, EarlyView., 2023
In the present study, we created the weight gain models with Min and Yorkshire pigs and conducted the metagenomics and metabolomics of colon contents and transcriptomics of colon tissue. Further, we revealed the characteristics and functions of the colonic microbiota in Min and Yorkshire pigs and analyzed their interactions with the host. Overall, this
Xiaoyu Huang   +6 more
wiley   +1 more source

Research Advance in Intestinal Mucosal Barrier and Pathogenesis of Crohn’s Disease

open access: yesGastroenterology Research and Practice, 2016
To date, the etiology and pathogenesis of Crohn’s disease (CD) have not been fully elucidated. It is widely accepted that genetic, immune, and environment factors are closely related to the development of CD. As an important defensive line for human body
Kuan Wang   +5 more
doaj   +1 more source

Myocardial regeneration after implantation of porcine small intestinal submucosa in the left ventricle

open access: yesBrazilian Journal of Cardiovascular Surgery, 2014
Introduction: Most cardiomyocytes do not regenerate after myocardial infarction. Porcine small intestinal submucosa has been shown to be effective in tissue repair.
Cassiana Maria Garcez Ramos   +12 more
doaj   +1 more source

AhR‐Dependent Induction of β‐Defensin 1 in Colonic Epithelial Cells Regulates Cross‐Talk between Gut Microbiota and Immune Response Leading to Attenuation of Colitis

open access: yesAdvanced Science, EarlyView.
This study identifies a key signaling pathway involving the environmental sensor AhR and antimicrobial peptides, such as BD‐1, in the regulation of intestinal homeostasis. It highlights the role of BD‐1 in regulating gut microbiota and the intestinal immune response.
Manikandan Palrasu   +16 more
wiley   +1 more source

MugenNet: A Novel Combined Convolution Neural Network and Transformer Network with its Application for Colonic Polyp Image Segmentation [PDF]

open access: yesarXiv
Biomedical image segmentation is a very important part in disease diagnosis. The term "colonic polyps" refers to polypoid lesions that occur on the surface of the colonic mucosa within the intestinal lumen. In clinical practice, early detection of polyps is conducted through colonoscopy examinations and biomedical image processing.
arxiv  

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