Results 11 to 20 of about 1,145,868 (311)
Regulation of psoriasis, colitis, and the intestinal microbiota by clusterin
Scientific Reports, 2023 Psoriasis, a chronic and systemic inflammatory disorder characterized by activation of the interleukin (IL)-23/IL-17 axis, may be associated with the intestinal microbiota through the so-called “gut–skin axis.” Clusterin is a glycoprotein ubiquitously ...
Yu Kyung Jun +11 more
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Reduced diversity of intestinal T-cell receptor repertoire in patients with Crohn’s disease
Frontiers in Cellular and Infection Microbiology, 2022 BackgroundThe intestinal microenvironment directly determines the human T-cell receptor (TCR) repertoire. Despite its extreme diversity, TCR repertoire analysis may provide a better understanding of the immune system in patients with inflammatory bowel ...
Sung Noh Hong +7 more
doaj +1 more source
Gut microbes, 2020 Little is known about the regulatory effect of microbiota on the proliferation and regeneration of ISCs. Here, we found that L. reuteri stimulated the proliferation of intestinal epithelia by increasing the expression of R-spondins and thus activating ...
Haiqin Wu +6 more
semanticscholar +1 more source
Frontiers in Bioengineering and Biotechnology, 2020 The Caco-2 monolayer is the most widely used in vitro model of the human intestinal mucosa to study absorption. However, models lack communication from other cells present in the native intestine, such as signals from fibroblasts in the lamina propria ...
N. Darling +4 more
semanticscholar +1 more source
The intestinal γδ T cells: functions in the gut and in the distant organs
Frontiers in Immunology, 2023 Located in the frontline against the largest population of microbiota, the intestinal mucosa of mammals has evolved to become an effective immune system.
Guo-Qing Li +9 more
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IgG “Detoxes” the Intestinal Mucosa [PDF]
Cell Host & Microbe, 2015 Secretory IgA is important in mucosal defense, but other, incompletely understood effectors exist. In this issue of Cell Host & Microbe, Kamada et al. (2015) show that IgG antibodies are produced against surface virulence factors of an intestinal attaching/effacing pathogen, bind to bacteria localized at the epithelium, and direct their destruction by ...
Eckmann, Lars, Stappenbeck, Thaddeus S.
openaire +2 more sources
Veterinary Research, 2020 Akkermansia muciniphila, a novel mucin-degrading bacterium, has been demonstrated to prevent the development of obesity and related complications. However, whether it can protect poultry from intestinal mucosal damage by enteropathogens has never been ...
Linda Zhu +5 more
semanticscholar +1 more source
Oxidative Medicine and Cellular Longevity, 2020 To explore the effect of selenium-enriched yeast (SeY) on intestinal barrier functions in weaned pigs upon oxidative stress, a 2 × 2 factorial design was utilized and thirty-two pigs were randomly assigned into four groups.
Lei Liu +11 more
semanticscholar +1 more source
PLoS ONE, 2021 Interaction of Clostridioides difficile spores with the intestinal mucosa contributes to the persistence and recurrence of the infection. Advanced age is one of the main risk factors for C. difficile infection and recurrence of the disease.
Pablo Castro-Córdova +2 more
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Myosin light chain kinase mediates intestinal barrier disruption following burn injury. [PDF]
PLoS ONE, 2012 BACKGROUND: Severe burn injury results in the loss of intestinal barrier function, however, the underlying mechanism remains unclear. Myosin light chain (MLC) phosphorylation mediated by MLC kinase (MLCK) is critical to the pathophysiological regulation ...
Chuanli Chen +4 more
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