Results 41 to 50 of about 724,233 (307)
Metabolism of Chenodeoxycholate by Intestinal Mucosa
Gastroenterology, 1976 The metabolism of 14C-labeled bile salts was studied in vitro during their absorption from infused segments of rat intestine. The transported bile salts were recovered in transudates which were collected from the serosal surface of infused segments. In the jejunum, 36% of transported [14C]deoxycholate and 48% of transported [14C]chenodeoxycholate were
D, Rachmilewitz, D R, Saunders
openaire +2 more sources
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Research progress of
Siliao yanjiu, 2021 Clostridium butyricum is a beneficial bacteria in intestines of animals. The butyric acid secreted by Clostridium butyricum can repair damaged intestinal mucosa, eliminate inflammation and nourish the intestines.
Zi-jie ZHANG +7 more
doaj
Animals, 2021 Some Enterococcus faecalis and E. faecium strains are used as probiotics or feed additives. Adherence to the intestinal mucosa is considered a crucial step for intestinal bacteria to colonize and further interact with the host epithelium and the immune ...
Mohsen Hanifeh +5 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
, 2022 Proliferative activity of stem cells of the intestinal crypts of the intestinal mucosa epithelium (KI—Ki67 positive cells) and apoptosis of intestinal villi epithelial cells in the mucosa (AC—apoptotic cells) in the proximal, middle, and distal segments ...
Jarosław Woliński (4097539) +4 more
core +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Lactobacillus salivarius reverse antibiotic-induced lung defense impairment in a ventilator model
Journal of Translational Medicine, 2018 Background Widespread use of antibiotics in the intensive care unit is a potential cause of the emergence of hospital-acquired pneumonia. This study determined whether Lactobacillus salivarius feeding could reverse antibiotic-induced lung defense ...
Tzyy-Bin Tsay +4 more
doaj +1 more source
IHC determination of c-kit in the intestinal mucosa.
, 2016 Original magnification, ×40. Numerous positive cells are displayed in the intestinal mucosa in the rats of NC and MC+TGP groups (A, C). Only few positive cells are observed in the intestinal mucosa of the STC animals (B). Arrow: positive cells.
Yongsheng Zhang (307948) +5 more
core +1 more source