Results 61 to 70 of about 1,145,868 (311)

The Potential Role of Gut-Derived Inflammation in Multiple System Atrophy

Journal of Parkinson’s Disease, 2017
Background: Recent evidence suggests that Parkinson’s disease (PD) is associated with intestinal microbiota dysbiosis, abnormal intestinal permeability, and intestinal inflammation.
Phillip A. Engen, Hemraj B. Dodiya, Ankur Naqib, Christopher B. Forsyth, Stefan J. Green, Robin M. Voigt, Jeffrey H. Kordower, Ece A. Mutlu, Kathleen M. Shannon, Ali Keshavarzian   +9 more
doaj   +1 more source

TMPRSS2 and TMPRSS4 mediate SARS-CoV-2 infection of human small intestinal enterocytes

bioRxiv, 2020
Both gastrointestinal symptoms and fecal shedding of SARS-CoV-2 RNA have been frequently observed in COVID-19 patients. However, whether SARS-CoV-2 replicate in the human intestine and its clinical relevance to potential fecal-oral transmission remain ...
Ruochen Zang, M. G. Castro, B. McCune, Q. Zeng, Paul W. Rothlauf, Naomi M. Sonnek, Zhuoming Liu, Kevin F. Brulois, Xin Wang, H. Greenberg, M. Diamond, Matthew A. Ciorba, S. Whelan, Siyuan Ding   +13 more
semanticscholar   +1 more source

A Novel Decellularized Fibrocartilage Graft Promotes Tympanic Membrane Repair

Advanced Healthcare Materials, EarlyView.
An off‐the‐shelf decellularized porcine meniscus fibrocartilage graft (MEND) is engineered for pediatric tympanoplasty. Featuring a microchannel architecture that promotes host cell invasion, MEND rapidly closes tympanic membrane perforations and fully remodels in vivo, outperforming fascia and matching cartilage grafts while avoiding donor‐site ...
Paul M. Gehret, Ryan M. Friedman, Gautham Nair, Stephanie L. Fung, Dana D. Ragbirsingh, John Germiller, Riccardo Gottardi   +6 more
wiley   +1 more source

Dysbiosis of Fungal Microbiota in the Intestinal Mucosa of Patients with Colorectal Adenomas

Scientific Reports, 2015
The fungal microbiota is an important component of the human gut microbiome and may be linked to gastrointestinal disease. In this study, the fungal microbiota of biopsy samples from adenomas and adjacent tissues was characterized by deep sequencing ...
Chunguang Luan, L. Xie, Xi Yang, Huifang Miao, Na Lv, Ruifen Zhang, Xue Xiao, Yongfei Hu, Yulan Liu, Na Wu, Yuanmin Zhu, B. Zhu   +11 more
semanticscholar   +1 more source

Co‐Electrospinning Extracellular Matrix with Polycaprolactone Enables a Modular Approach to Balance Bioactivity and Mechanics of a Multifunctional Bone Wrap

Advanced Healthcare Materials, EarlyView.
The incorporation of nondigested ECM and synthetic polymers into a co‐electrospinning system enables the decoupling of bioactivity and mechanical properties within a single wrap. This technique is used to develop a multifunctional bone wrap that achieves augmented membrane durability, sustained infection control, and enhanced vascularity for use in ...
Sarah Jones, Madeline Laude, Zeenat Oyebanji, Ruchi Birur, Andres Luengo Martinez, Isabelle Gilbert, Phillip Baek, Nichole Longbottom, Nicole McCullough, Staci J. Horn, Chien‐Yu Lin, Matthew J. Lohr, Fred Clubb, Manuel K. Rausch, Elizabeth Cosgriff‐Hernandez   +14 more
wiley   +1 more source

Regulation of apoptosis is impaired in atrophic gastritis associated with gastric cancer

BMC Gastroenterology, 2017
Background Gastric premalignant conditions, atrophic gastritis (AG) and intestinal metaplasia (IM) are characterized by an increase of proliferation and a reduction of apoptosis in epithelial cells.
R. Rosania, M. Varbanova, T. Wex, C. Langner, J. Bornschein, F. Giorgio, E. Ierardi, P. Malfertheiner   +7 more
doaj   +1 more source

Bioinspired Adaptive Sensors: A Review on Current Developments in Theory and Application

Advanced Materials, EarlyView.
This review comprehensively summarizes the recent progress in the design and fabrication of sensory‐adaptation‐inspired devices and highlights their valuable applications in electronic skin, wearable electronics, and machine vision. The existing challenges and future directions are addressed in aspects such as device performance optimization ...
Guodong Gong, You Zhou, Qingxiu Li, Wenyu Zhao, Sunyingyue Geng, Hangfei Li, Yan‐Bing Leng, Shirui Zhu, Guanglong Ding, Yongbiao Zhai, Ziyu Lv, Ye Zhou, Su‐Ting Han   +12 more
wiley   +1 more source

Effects of Aging on the Microbiota and Inflammatory Status of the Intestinal and Oviductal Mucosa in Laying Hens

The Journal of Poultry Science
Aging and inflammation of the intestinal and oviductal mucosa reduce egg production in laying hens. In mammals, microbiota changes in the intestine and reproductive mucosa are linked to aging and mucosal inflammation, but this ...
Takahiro Nii, Takumi Sugiura, Naoki Suzuki, Naoki Isobe, Yukinori Yoshimura   +4 more
doaj   +1 more source

Short segment Barrett's esophagus and distal gastric intestinal metaplasia Esôfago de Barrett de segmento curto e metaplasia intestinal gástrica distal

Arquivos de Gastroenterologia, 2006
BACKGROUND: Short segment Barrett's esophagus is defined by the presence of
Judite Dietz, Sílvia Chaves-e-Silva, Luíse Meurer, Setsuo Sekine, Andréa Ribeiro de Souza, Gilmara Coelho Meine   +5 more
doaj   +1 more source

Rapid Fabrication of Self‐Propelled and Steerable Magnetic Microcatheters for Precision Medicine

Advanced Materials, EarlyView.
A rapid Joule heating fabrication method for the production of self‐propelling, adaptive microcatheters, with tunable stiffness and integrated microfluidic channels is presented. Demonstrated through three microrobotic designs, including a steerable guiding catheter, an untethered wave‐crawling TubeBot, and a distal‐end propelled microcatheter, it was ...
Zhi Chen, Boris Rivkin, David Castellanos‐Robles, Ivan Soldatov, Lukas Beyer, Mariana Medina‐Sánchez   +5 more
wiley   +1 more source