Results 51 to 60 of about 724,233 (307)

Reduction of colonic inflammation in HLA-B27 transgenic rats by feeding Marie Ménard apples, rich in polyphenols [PDF]

, 2009
Inflammatory bowel diseases (IBD) are immunomediated ailments affecting millions of individuals. Although diet is regarded as an important factor influencing IBD, there are no accepted dietary recommendations presently available.
Luceri, C., Castagnini, C., Martin, R., Evelo, C.T.; id_orcid, Zoetendal, E.G., Messerini, L., Eijssen, L., Caderni, G., Femia, A.P., Eijssen, L.M.; id_orcid, Renard, C.M., Giovannelli, L., Gaj, S., Evelo, C., Bigagli, E., Baron, A., Toti, S., Lodovici, M., Salvadori, M., Dolara, P., Pitozzi, V.   +20 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Histopathological changes of chronic cestodes infection in local domesticated ducks (Anas platyrhynchas) in Baghdad city.

The Iraqi Journal of Veterinary Medicine, 2019
This study was conducted to investigate the histopathological changes of cestodes chronic intestinal infections in ten local domesticated ducks (Anas platyrhynchas) during the period 1/9/2016- 1/10/2017 in Baghdad city.
Haider Mohammed Ali Al-Rubaie
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

The Potential Role of Gut-Derived Inflammation in Multiple System Atrophy

Journal of Parkinson’s Disease, 2017
Background: Recent evidence suggests that Parkinson’s disease (PD) is associated with intestinal microbiota dysbiosis, abnormal intestinal permeability, and intestinal inflammation.
Phillip A. Engen, Hemraj B. Dodiya, Ankur Naqib, Christopher B. Forsyth, Stefan J. Green, Robin M. Voigt, Jeffrey H. Kordower, Ece A. Mutlu, Kathleen M. Shannon, Ali Keshavarzian   +9 more
doaj   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Effects of Aging on the Microbiota and Inflammatory Status of the Intestinal and Oviductal Mucosa in Laying Hens

The Journal of Poultry Science
Aging and inflammation of the intestinal and oviductal mucosa reduce egg production in laying hens. In mammals, microbiota changes in the intestine and reproductive mucosa are linked to aging and mucosal inflammation, but this ...
Takahiro Nii, Takumi Sugiura, Naoki Suzuki, Naoki Isobe, Yukinori Yoshimura   +4 more
doaj   +1 more source

Regulation of apoptosis is impaired in atrophic gastritis associated with gastric cancer

BMC Gastroenterology, 2017
Background Gastric premalignant conditions, atrophic gastritis (AG) and intestinal metaplasia (IM) are characterized by an increase of proliferation and a reduction of apoptosis in epithelial cells.
R. Rosania, M. Varbanova, T. Wex, C. Langner, J. Bornschein, F. Giorgio, E. Ierardi, P. Malfertheiner   +7 more
doaj   +1 more source

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin, Tianyuan Yang, Minglei Liu, Haiyang Luo, Jing Yuan, Ke Zhang, Xinsheng Han, Jing Yang, Yuming Xu   +8 more
wiley   +1 more source

Eosinophilic myenteric ganglionitis is associated with functional intestinal obstruction [PDF]

, 2003
The diagnostic features and clinical course of three children (aged 1 month to 15 years) with severe functional intestinal obstruction and inflammation of the colonic lamina propria and myenteric plexus are described.
Smith, VV, Lindley, KJ, Milla, PJ, Schappi, MG   +3 more
core