Results 31 to 40 of about 198,094 (268)
Regulation of IgA Production by Intestinal Dendritic Cells and Related Cells
Frontiers in Immunology, 2019 The intestinal mucosa is a physiological barrier for most microbes, including both commensal bacteria and invading pathogens. Under homeostatic conditions, immunoglobulin A (IgA) is the major immunoglobulin isotype in the intestinal mucosa.
Hiroyuki Tezuka, Toshiaki Ohteki
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Research progress of
Siliao yanjiu, 2021 Clostridium butyricum is a beneficial bacteria in intestines of animals. The butyric acid secreted by Clostridium butyricum can repair damaged intestinal mucosa, eliminate inflammation and nourish the intestines.
Zi-jie ZHANG +7 more
doaj
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Animals, 2021 Some Enterococcus faecalis and E. faecium strains are used as probiotics or feed additives. Adherence to the intestinal mucosa is considered a crucial step for intestinal bacteria to colonize and further interact with the host epithelium and the immune ...
Mohsen Hanifeh +5 more
doaj +1 more source
Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
Lactobacillus salivarius reverse antibiotic-induced lung defense impairment in a ventilator model
Journal of Translational Medicine, 2018 Background Widespread use of antibiotics in the intensive care unit is a potential cause of the emergence of hospital-acquired pneumonia. This study determined whether Lactobacillus salivarius feeding could reverse antibiotic-induced lung defense ...
Tzyy-Bin Tsay +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
The Potential Role of Gut-Derived Inflammation in Multiple System Atrophy
Journal of Parkinson’s Disease, 2017 Background: Recent evidence suggests that Parkinson’s disease (PD) is associated with intestinal microbiota dysbiosis, abnormal intestinal permeability, and intestinal inflammation.
Phillip A. Engen +9 more
doaj +1 more source
The Iraqi Journal of Veterinary Medicine, 2019 This study was conducted to investigate the histopathological changes of cestodes chronic intestinal infections in ten local domesticated ducks (Anas platyrhynchas) during the period 1/9/2016- 1/10/2017 in Baghdad city.
Haider Mohammed Ali Al-Rubaie
doaj +1 more source