Results 31 to 40 of about 1,145,868 (311)

Metabolism of Chenodeoxycholate by Intestinal Mucosa

open access: yesGastroenterology, 1976
The metabolism of 14C-labeled bile salts was studied in vitro during their absorption from infused segments of rat intestine. The transported bile salts were recovered in transudates which were collected from the serosal surface of infused segments. In the jejunum, 36% of transported [14C]deoxycholate and 48% of transported [14C]chenodeoxycholate were
D, Rachmilewitz, D R, Saunders
openaire   +2 more sources

Protective Effect and Mechanisms of Radix Astragali Injection on the Intestinal Mucosa of Rats with Obstructive Jaundice

open access: yesMediators of Inflammation, 2010
Objective. To research the protective effects and mechanisms of Radix Astragali injection on the intestinal mucosa of rats with obstructive jaundice (OJ). Methods.
Zhang Xiping   +4 more
doaj   +1 more source

The role of intestinal microbes on intestinal barrier function and host immunity from a metabolite perspective

open access: yesFrontiers in Immunology, 2023
The gut is colonized by many commensal microorganisms, and the diversity and metabolic patterns of microorganisms profoundly influence the intestinal health.
Yifeng Fu, Jin Lyu, Shuangshuang Wang
semanticscholar   +1 more source

Intestinal Barrier in Human Health and Disease

open access: yesInternational Journal of Environmental Research and Public Health, 2021
The intestinal mucosa provides a selective permeable barrier for nutrient absorption and protection from external factors. It consists of epithelial cells, immune cells and their secretions. The gut microbiota participates in regulating the integrity and
Natalia Di Tommaso   +2 more
semanticscholar   +1 more source

Transcriptional and Molecular Pathways Activated in Mesenteric Adipose Tissue and Intestinal Mucosa of Crohn’s Disease Patients

open access: yesInternational Journal of Inflammation, 2017
Crohn’s disease (CD) is a chronic inflammatory disorder, characterized by cytokine imbalance and transcription signaling pathways activation. In addition, the increase of mesenteric adipose tissue (MAT) near the affected intestinal area is a hallmark of ...
Andressa Coope   +11 more
doaj   +1 more source

Changes of biochemical parameters in rat intestinal mucosa induced by methotrexate and effects of enteral administration of glutamine [PDF]

open access: yesArchive of Oncology, 2004
BACKGROUND: Rapidly proliferating crypt cells of the intestinal epithelium, the precursors of the mature enterocytes, are extremely sensitive to the effects of cytostatic agents. We investigated the effects of the methotrexate on rat intestinal mucosa in
Bajin-Katić Katica   +2 more
doaj   +1 more source

Activation of Immune and Defense Responses in the Intestinal Mucosa by Outer Membrane Vesicles of Commensal and Probiotic Escherichia coli Strains

open access: yesFrontiers in Microbiology, 2016
The influence of microbiota in human health is well-known. Imbalances in microbiome structure have been linked to several diseases. Modulation of microbiota composition through probiotic therapy is an attempt to harness the beneficial effects of ...
María-José Fábrega   +7 more
semanticscholar   +1 more source

Effects of Dietary Supplementation with Glutamine on the Immunity and Intestinal Barrier Gene Expression in Broiler Chickens Infected with Salmonella Enteritidis

open access: yesAnimals, 2022
The effects of glutamine (Gln) on immunity and intestinal barrier gene expression levels in broilers challenged with Salmonella Enteritidis were evaluated.
Qiujue Wu   +6 more
doaj   +1 more source

Potential role of mesenchymal stem cells in alleviating intestinal ischemia/reperfusion impairment. [PDF]

open access: yesPLoS ONE, 2013
BACKGROUND: Transplantation of bone marrow mesenchymal stem cells (MSCs) provides a promising therapeutic efficiency for a variety of disorders caused by ischemia or reperfusion impairment.
Haitao Jiang   +5 more
doaj   +1 more source

Biotransformation of xenobiotics in human intestinal mucosa [PDF]

open access: yesEnvironmental Health Perspectives, 1979
Drug-metabolizing enzymes, especially monooxygenases, play a major role in biotransformation and detoxification of many foreign compounds including environmental carcinogens. Although largely localized in the liver they are also found in the small intestine, which is the portal of entry of dietary toxins.
H P, Hoensch, R, Hutt, F, Hartmann
openaire   +2 more sources

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