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Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi+3 more
wiley +1 more source
Prediction model for irreversible intestinal ischemia in strangulated bowel obstruction
Background Preoperatively diagnosing irreversible intestinal ischemia in patients with strangulated bowel obstruction is difficult. Therefore, this study aimed to establish a prediction model for irreversible intestinal ischemia in strangulated bowel ...
Toshimichi Kobayashi+11 more
doaj +1 more source
Mitochondrial neurogastrointestinal encephalomyopathy: approaches to diagnosis and treatment [PDF]
Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is an ultra-rare disease caused by mutations in TYMP, the gene encoding for the enzyme thymidine phosphorylase.
Bax, BE
core +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
[Objectives] To analyze the influencing factors for postoperative intestinal obstruction of colorectal cancer and construct a prediction model. [Methods] A retrospective analysis was conducted on 300 patients with colorectal cancer admitted to our ...
Wang Zhen+5 more
doaj +1 more source
EFSUMB Recommendations and Guidelines for Gastrointestinal Ultrasound - Part 1: Examination Techniques and Normal Findings (Long version). [PDF]
▼ In October 2014 the European Federation of Societies for Ultrasound in Medicine and Biology formed a Gastrointestinal Ultrasound (GIUS) task force group to promote the use of GIUS in a clinical setting.
Calabrese, E.+16 more
core +5 more sources
A Rare Case of Foreign Body Ingestion, Mimicking as Mesenteric Cyst. "Case Report" [PDF]
Background: Foreign body ingestion by children is a commonly encountered problem and accounts for a significant emergency visits among pediatric population.
Hashim, I. (Imran)+5 more
core
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Risk factors of intestinal obstruction in pregnancy [PDF]
<p>Objective: to study risk factors and options for clinical course of acute intestinal obstruction in pregnancy. Materials and methods. A detailed study of history, clinical course, diagnosis and treatment characteristics of acute intestinal ...
Khvorostukhina N.F.+3 more
doaj
44-year-old female known case of Crohn’s disease and depression who presented with a few hours’ history of severe abdominal pain and multiple episodes of vomiting faeculant matter.
Abela, Franklin, Dimech, Anthony Pio
core +1 more source