Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze+3 more
wiley +1 more source
Biochemical disorders in patients with strangulated abdominal hernias, complicatedby acute intestinal obstruction [PDF]
Existing literature sources related to the problem of strangulated hernias are contradictory. Specific attention is paid to intestinal obstruction as a complication of strangulated hernias.
Karliychuk, O.O.+3 more
core
The power of microRNA regulation—insights into immunity and metabolism
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto+2 more
wiley +1 more source
Adult-onset Still’s disease (AOSD) is a rare autoinflammatory disorder that can lead to a cytokine storm, causing a range of symptoms. Acute intestinal pseudo-obstruction is another rare condition that results in intestinal obstruction without anatomical
Pierre Rossignon, Alain Soupart
doaj +1 more source
An intriguing autopsy case of gangrene intestine [PDF]
Background Hashimoto’s thyroiditis is one of the most common causes of hypothyroidism. Hypothyroidism is a known cause of hyperlipidemia. There is a strong correlation between coronary and mesenteric vessel atherosclerosis.
E., E.Jayashankar+4 more
core
Correlation between capillary oxygen saturation and small intestinal wall thickness in the equine colic patient [PDF]
The surgical evaluation of haemorrhagic infarcted intestine and the decision for or against bowel resection require a lot of experience and are subjective.
Kunzmann, Robert+4 more
core +1 more source
Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner+7 more
wiley +1 more source
Oclusão intestinal por compressas cirúrgicas intraluminais: experiência de cinco casos
Despite being unusual, retained foreign bodies after surgical procedures is a matter of great concern for surgeons. The main purpose of this article is to describe five cases of intestinal obstruction due to intraluminal surgical sponges.
Christiano Marlo Paggi Claus+3 more
doaj +1 more source
Eosinophilic Gastroenteritis Presenting as Intestinal Obstruction - A Case Series. [PDF]
Eosinophilic Gastroenteritis is a rare disease characterized by infiltration of the gastrointestinal tract by an increased number of eosinophils as compared to the normal.
Amitha, K, Kumar, AD, Shariff, SA
core +1 more source
Cystic fibrosis mice carrying the missense mutation G551D replicate human genotype phenotype correlations [PDF]
We have generated a mouse carrying the human G551D mutation in the cystic fibrosis transmembrane conductance regulator gene (CFTR) by a one-step gene targeting procedure.
Alton, Ewfw+11 more
core +2 more sources