Results 51 to 60 of about 204,119 (341)
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
FEBS Letters, EarlyView.The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
Desmoid tumour: a rare etiology of intestinal obstruction
The Pan African Medical Journal, 2015 Intestinal obstruction is a frequently encountered entity in surgical practice. The signs and symptoms, many a times, are suggestive of the level of obstruction, making the diagnosis of obstruction evident.
Gaurav Aggarwal +3 more
doaj +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
A Case Report: Intestinal Obstruction Due to Acute Appendicitis [PDF]
, 2010 Appendicitis has always been the most common surgical case in our daily practices; however, appendicitis presenting mechanical intestinal obstruction is quite rare and it has never been reported in Immanuel Hospital. In this report we present a young man
Pangayoman, R. A. (Roys)
core
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Etiological Spectrum of Dynamic Intestinal Obstruction
Gomal Journal of Medical Sciences, 2004 Background: Intestinal obstruction is a common and potentially dangerous surgical emergency with high morbidity and mortality if managed inappropriately. It is essential to distinguish between its various types. The aim of this study was to determine the
Tariq Wahab Khanzada +2 more
doaj
Journal of Clinical QuestionBackground: Kawasaki disease (KD) is an acute febrile vasculitis that predominantly affects children under 5 years of age. Although gastrointestinal symptoms are common, severe complications, such as intestinal obstruction, are rare but clinically ...
Yuta Baba +6 more
doaj +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Effects of Single-Dose Prucalopride on Intestinal Hypomotility in Horses: Preliminary Observations [PDF]
, 2017 Abnormalities of gastrointestinal motility are often a challenge in horses; however, the use of prokinetic drugs in such conditions must be firmly established yet.
Bassotti, G. +7 more
core +2 more sources
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source