Results 101 to 110 of about 843,325 (293)
Data mining methods for the prediction of intestinal absorption using QSAR [PDF]
, 2014 Oral administration is the most common route for administration of drugs. With the growing cost of drug discovery, the development of Quantitative Structure-Activity Relationships (QSAR) as computational methods to predict oral absorption is highly ...
Newby, Danielle Anne
core
Intestinal permeability in normally nourished and malnourished children with and without diarrhea
, 2013 We evaluated the association between diarrhea, malnutrition and intestinal function using the lactulose-mannitol test. Our study showed that a third of all children have abnormal intestinal permeability, there was an expected increase of permeability in ...
Bose, A. +3 more
core +1 more source
Advanced Healthcare Materials, EarlyView.NeuroVisio SyncPatch integrates skin‐conformal electromyography (EMG) electrodes with camera‐tracked markers to jointly assess muscle activity and three‐dimensional knee kinematics during rehabilitation. Parallel feedback pathways provide real‐time kinematic guidance during movement and post‐trial neuromuscular feedback.
Bohyung Choi +11 more
wiley +1 more source
Mouse intestinal epithelial cell monolayers ex vivo to assess intestinal permeability in peanut allergy [PDF]
Peanut allergy is increasing in prevalence and, compared to other food allergens, more frequently causes severe allergic reactions. There are no effective methods to predict the severity of food allergic reactions.
Huan, Benjamin
core +1 more source
Atom‐Efficient Cerium‐Based Molecular Cages as Biocompatible Reactive Oxygen Scavengers
Advanced Healthcare Materials, EarlyView.Discrete mixed‐valent cerium molecular cages organize accessible redox centers within confined coordination environments and scavenge superoxide, hydrogen peroxide, and hydroxyl radicals. Encapsulation of the lead cage in an ROS‐responsive DTP nanoplatform enables lesion‐associated delivery, attenuates macrophage oxidative stress and inflammation, and ...
Chao Li +9 more
wiley +1 more source
Intestinal Permeability, Irritable Bowel Syndrome with Constipation, and the Role of Sodium-Hydrogen Exchanger Isoform 3 (NHE3) [PDF]
Brian E Lacy,1 David Rosenbaum,2 Susan Edelstein,2 Kenji Kozuka,2 Laura A Williams,2 David C Kunkel3 1Division of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, FL, USA; 2Ardelyx, Inc, Waltham, MA, USA; 3Division of Gastroenterology ...
Lacy BE +5 more
core
Hyperuricemia drives intestinal barrier dysfunction by regulating gut microbiota
HeliyonBackground: Hyperuricemia elevates gut permeability; however, the risk of its influence on the compromised intestinal barrier is poorly understood. Aims: This study was carried out, aiming to elucidate the orchestrators and disruptors of intestinal ...
Xiaomin Yang +6 more
doaj +1 more source
Intestinal Permeability in Dermatitis Herpetiformis
Journal of Investigative Dermatology, 1988 Differential absorption of D-xylose and 3-0-methyl-D-glucose, and unmediated intestinal permeation (simple diffusion) of lactulose and L-rhamnose, have been investigated in 20 patients with dermatitis herpetiformis. Both iso-osmolar and hyperosmolar test solutions were employed and the results were compared with those obtained from a group of healthy ...
Griffiths, Christopher E.M. +4 more
openaire +2 more sources
Crystal-liquid Fugacity Ratio as a Surrogate Parameter for Intestinal Permeability
Journal of Pharmacy & Pharmaceutical Sciences, 2016 Background: We assessed the feasibility of using crystal-liquid fugacity ratio (CLFR) as an alternative parameter for intestinal permeability in the biopharmaceutical classification (BCS) of passively absorbed drugs.
Parvin Zakeri-Milani +6 more
doaj +1 more source