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Intestinal Barrier in Human Health and Disease [PDF]
International Journal of Environmental Research and Public Health, 2021 The intestinal mucosa provides a selective permeable barrier for nutrient absorption and protection from external factors. It consists of epithelial cells, immune cells and their secretions. The gut microbiota participates in regulating the integrity and function of the intestinal barrier in a homeostatic balance.
Antonio Gasbarrini +1 more
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IL-1β and the Intestinal Epithelial Tight Junction Barrier
Frontiers in Immunology, 2021 The intestinal epithelial tight junction (TJ) barrier controls the paracellular permeation of contents from the intestinal lumen into the intestinal tissue and systemic circulation.
Lauren W. Kaminsky +2 more
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Rapamycin Prevents Sulfate-Reducing Bacteria-Induced Effects on Snail and GSK-3 and Impaired Intestinal Barrier [PDF]
MicroorganismsDesulfovibrio spp. are sulfate-reducing bacteria (SRB) associated with conditions such as inflammatory bowel disease (IBD) that are linked to intestinal barrier dysfunction (leaky gut).
Sudha B. Singh +3 more
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The Compromised Intestinal Barrier Induced by Mycotoxins
Toxins, 2020 Mycotoxins are fungal metabolites that occur in human foods and animal feeds, potentially threatening human and animal health. The intestine is considered as the first barrier against these external contaminants, and it consists of interconnected ...
Yanan Gao +4 more
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Intestinal Barrier, Claudins and Mycotoxins [PDF]
Toxins, 2021 The intestinal barrier is the main barrier against all of the substances that enter the body. Proper functioning of this barrier guarantees maintained balance in the organism. Mycotoxins are toxic, secondary fungi metabolites, that have a negative impact both on human and animal health.
Marta Justyna Kozieł +2 more
openaire +3 more sources
Role of the Intestinal Microbiome, Intestinal Barrier and Psychobiotics in Depression [PDF]
Nutrients, 2021 The intestinal microbiota plays an important role in the pathophysiology of depression. As determined, the microbiota influences the shaping and modulation of the functioning of the gut–brain axis. The intestinal microbiota has a significant impact on processes related to neurotransmitter synthesis, the myelination of neurons in the prefrontal cortex ...
Paulina Trzeciak, Mariola Herbet
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Carotenoid metabolism at the intestinal barrier [PDF]
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2020 Carotenoids exert a rich variety of physiological functions in mammals and are beneficial for human health. These lipids are acquired from the diet and metabolized to apocarotenoids, including retinoids (vitamin A and its metabolites). The small intestine is a major site for their absorption and bioconversion.
Johannes, von Lintig +3 more
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Stromal regulation of the intestinal barrier
Mucosal Immunology, 2023 The intestinal barrier is a complex structure that allows the absorption of nutrients while ensuring protection against intestinal pathogens and balanced immunity. The development and maintenance of a functional intestinal barrier is a multifactorial process that is only partially understood.
Sylvestre, Marvin +2 more
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Journal of Immunology Research, 2022 Objectives. Intestinal epithelial barrier function is an important mechanical barrier to maintain intestinal homeostasis and resist the invasion of intestinal pathogens and microorganisms.
Yuejin Li +7 more
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Pharmacological Research, 2023 Succinate is a vital signaling metabolite produced by the host and gut microbiota. Succinate has been shown to regulate host metabolic homeostasis and inhibit obesity-associated inflammation in macrophages by engaging its cognate receptor, SUCNR1 ...
Xuan Li +6 more
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