Results 41 to 50 of about 357,808 (308)
LRH-1 mitigates intestinal inflammatory disease by maintaining epithelial homeostasis and cell survival. [PDF]
, 2018 Epithelial dysfunction and crypt destruction are defining features of inflammatory bowel disease (IBD). However, current IBD therapies targeting epithelial dysfunction are lacking.
Bayrer, James R +8 more
core +2 more sources
PLK1 protects against sepsis-induced intestinal barrier dysfunction
Scientific Reports, 2018 Sepsis and sepsis-associated intestinal barrier dysfunction are common in intensive care units, with high mortality. The aim of this study is to investigate whether Polo-like kinase 1 (PLK1) ameliorates sepsis-induced intestinal barrier dysfunction in ...
Yingya Cao +7 more
doaj +1 more source
Intestinal barrier dysfunction in severe burn injury
Burns & Trauma, 2019 Severe burn injury is often accompanied by intestinal barrier dysfunction, which is closely associated with post-burn shock, bacterial translocation, systemic inflammatory response syndrome, hypercatabolism, sepsis, multiple organ dysfunction syndrome ...
Wen He, Yu Wang, Pei Wang, Fengjun Wang
doaj +1 more source
Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2020 Aim of review. Description of intestinal mucosal barrier permeability disruption causes as morbid factors in gastrointestinal tract (GIT) functional disorders.General provisions.
A. L. Kovaleva +2 more
doaj +1 more source
Mechanisms of Intestinal Barrier Dysfunction in Sepsis [PDF]
Shock, 2016 Intestinal barrier dysfunction is thought to contribute to the development of multiple organ dysfunction syndrome in sepsis. Although there are similarities in clinical course following sepsis, there are significant differences in the host response depending on the initiating organism and time course of the disease, and pathways of gut injury vary ...
Benyam P, Yoseph +9 more
openaire +2 more sources
Frontiers in NutritionIntroductionExisting studies have demonstrated a significant correlation between intestinal barrier and disease outcomes. The intestinal barrier is particularly susceptible to impairment following digestive surgery.
Jingjing Wang +6 more
doaj +1 more source
Gut microbiota-derived tryptophan metabolite indole-3-carboxaldehyde enhances intestinal barrier function via aryl hydrocarbon receptor/AMP-activated protein kinase signaling activation [PDF]
Animal BioscienceObjective Intestinal inflammatory diseases significantly affect animal health, primarily by disrupting intestinal barrier function. Indole-3-carboxaldehyde (IAld), a key metabolite of tryptophan derived from gut microbiota, exhibits protective properties
Donglin Shi +5 more
doaj +1 more source
Intestinal Barrier and Permeability in Health, Obesity and NAFLD
Biomedicines, 2021 The largest surface of the human body exposed to the external environment is the gut. At this level, the intestinal barrier includes luminal microbes, the mucin layer, gastrointestinal motility and secretion, enterocytes, immune cells, gut vascular ...
Piero Portincasa +7 more
doaj +1 more source
Lactoferrin Decreases the Intestinal Inflammation Triggered by a Soybean Meal-Based Diet in Zebrafish [PDF]
, 2016 Indexación: Web of ScienceIntestinal inflammation is a harmful condition in fish that can be triggered by the ingestion of soybean meal. Due to the positive costs-benefits ratio of including soybean meal in farmed fish diets, identifying additives with ...
Alaurent, Trevor G. S. +7 more
core +4 more sources
Frontiers in PhysiologyGut serves as the largest interface between humans and the environment, playing a crucial role in nutrient absorption and protection against harmful substances. The intestinal barrier acts as the initial defense mechanism against non-specific infections,
Hong-Yun Nie +14 more
doaj +1 more source