Results 51 to 60 of about 357,808 (308)

TLR/MyD88-Mediated Inflammation Induced in Porcine Intestinal Epithelial Cells by Ochratoxin A Affects Intestinal Barrier Function

open access: yesToxics, 2023
The intestinal epithelium performs vital functions such as nutrient absorption and acting as an intestinal barrier to maintain the host’s homeostasis. Mycotoxin, which affects the processing and storage of animal feedstuff, is a problematic pollutant in ...
Jung Woong Yoon   +4 more
doaj   +1 more source

Intestinal barriers to water-soluble macromolecules [PDF]

open access: yesEnvironmental Health Perspectives, 1979
Neonates of some species of mammals absorb water-soluble macromolecules from the lumen of the gut to the circulation. This is a means for providing the neonate with passive immunological protection. The accepted model for absorption of macromolecules, particularly immunoglobulin G (IgG), has at least three phases: adherence of the macromolecule to the ...
openaire   +2 more sources

Intestinal Mucin Glycosylation: Structural Regulation, Homeostasis Maintenance and Disease Association

open access: yesBiomolecules
The intestinal barrier is a complex configuration that defends against external assaults and maintains intestinal health. Disruption of barrier function can lead to intestinal inflammation and various diseases.
Yunye Li   +3 more
doaj   +1 more source

Effects of Docetaxel Injection and Docetaxel Micelles on the Intestinal Barrier and Intestinal Microbiota

open access: yesAdvanced Science, 2021
Increasing evidence has suggested that chemotherapeutics affect the integrity of the intestinal barrier and alter the intestinal microbiota, thus limiting the therapeutic outcomes of cancer chemotherapy.
Qingya Liu   +8 more
doaj   +1 more source

Campylobacter jejuni colonization promotes the translocation of Escherichia coli to extra-intestinal organs and disturbs the short-chain fatty acids profiles in the chicken gut [PDF]

open access: yes, 2019
For a long time Campylobacter was only considered as a commensal microorganism in avian hosts restricted to the ceca, without any pathogenic features. The precise reasons for the symptomless chicken carriers are still unknown, but investigations of the ...
Aschenbach, J. R.   +6 more
core   +1 more source

Blinatumomab Utilization in Pediatric B‐Cell Acute Lymphoblastic Leukemia: Experience From the Mountain West

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Blinatumomab is a bispecific T‐cell engager approved for the treatment of pediatric B‐cell acute lymphoblastic leukemia (B‐ALL). Outpatient home infusion reduces hospitalization burden and optimizes resource utilization, but is logistically challenging.
Angela Parra del Riego   +10 more
wiley   +1 more source

Disulfiram alleviates acute lung injury and related intestinal mucosal barrier impairment by targeting GSDMD-dependent pyroptosis

open access: yesJournal of Inflammation, 2022
Background Pyroptosis was implicated in acute lung injury (ALI). Disulfiram is reported as an effective pyroptosis inhibitor by inhibiting gasdermin D(GSDMD).
Jiping Zhao   +6 more
doaj   +1 more source

Critical Signaling Transduction Pathways and Intestinal Barrier: Implications for Pathophysiology and Therapeutics

open access: yesPharmaceuticals, 2023
The intestinal barrier is a sum of the functions and structures consisting of the intestinal mucosal epithelium, mucus, intestinal flora, secretory immunoglobulins, and digestive juices.
Jingwang Gao   +5 more
doaj   +1 more source

Th22 cells and the intestinal mucosal barrier

open access: yesFrontiers in Immunology, 2023
T-helper 22 (Th22) cells represent a novel subset of CD4+ T cells that exhibit distinctive characteristics, namely the secretion of IL-22 while abstaining from secreting IL-17 and interferon-γ (IFN-γ). These cells serve as the primary source of IL-22, and both Th22 cells and IL-22 are believed to play a role in maintaining intestinal mucosal ...
Jieli Chen, Jun Yao
openaire   +3 more sources

Supporting Survivor‐Centered Care Through Digital Health Integration

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Survivors of childhood cancer face barriers to receiving guideline‐based, long‐term follow‐up care. Two digital tools, Passport for Care (PFC) and Cancer SurvivorLink (SurvivorLink), address complementary gaps by enabling tailored survivorship care plan (SCP) generation, updating, storage, and sharing.
Jordan G. Marchak   +15 more
wiley   +1 more source

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