Results 1 to 10 of about 85,320 (110)
The Role of Intestinal Mucosal Barrier in Autoimmune Disease: A Potential Target
Frontiers in Immunology, 2022 Autoimmune diseases are a series of diseases involving multiple tissues and organs, characterized by the over production of abnormal multiple antibodies.
Jia An +7 more
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Journal of Advanced Research, 2023 Background: Previous studies have focused on the involvement of small nucleolar RNAs (snoRNAs) and SNHGs in tumor cell proliferation, apoptosis, invasion, and metastasis via multiple pathways, including phosphatidylinositol-3-kinase/protein kinase B ...
Tian Yang, Jun Shen
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Frontiers in Pharmacology, 2023 Damage to the intestinal mucosal barrier play an important role in the pathogenesis of ulcerative colitis (UC). Discovering the key regulators and repairing the disturbed barrier are crucial for preventing and treating UC.
Yichen Zong +5 more
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Benign regulation of short-chain fatty acids: the underlying mechanism of the beneficial effects of manual acupuncture on cognitive ability and the intestinal mucosal barrier in APP/PS1 mice [PDF]
Frontiers in NeuroscienceBackgroundGut microbiota dysbiosis is closely related to the occurrence and progression of Alzheimer’s disease (AD). The destruction of the intestinal mucosal barrier caused by a decrease in short-chain fatty acids (SCFAs) plays a key role in gut ...
Ning Ding +4 more
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Regulatory Role of IGF2BP2 in Intestinal Mucosal Barrier Dysfunction in Ulcerative Colitis [PDF]
The Turkish Journal of GastroenterologyBackground/Aims: Ulcerative colitis (UC), an idiopathic and chronic inflammatory disease, primarily targets the mucosal lining of the colon. This research endeavors to reveal the mechanism of insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2 ...
Ruifan Li, Bin Gu, Anli Lv
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Frontiers in MicrobiologyObjectiveThe aim of the study is to investigate the function and mechanism of Zinc Gluconate (ZG) on intestinal mucosal barrier damage in antibiotics and Lipopolysaccharide (LPS)-induced mice.MethodsWe established a composite mouse model by inducing ...
Yongcai Wang +10 more
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Intestinal Mucosal Mast Cells: Key Modulators of Barrier Function and Homeostasis
Cells, 2019 The gastrointestinal tract harbours the largest population of mast cells in the body; this highly specialised leukocyte cell type is able to adapt its phenotype and function to the microenvironment in which it resides.
Mercé Albert-Bayo +7 more
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Zhuanggu Shubi ointment mediated the characteristic bacteria-intestinal mucosal barrier-bone metabolism axis to intervene in postmenopausal osteoporosis [PDF]
Frontiers in Cellular and Infection MicrobiologyBackgroundZhuanggu Shubi ointment (ZGSBG) has good efficacy in postmenopausal osteoporosis (PMO), but the mechanism of efficacy involving gut microecology has not been elucidated.ObjectiveThis study investigated the mechanism of ZGSBG in regulating gut ...
Xiaoya Li +16 more
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Intestinal mucosal barrier: a potential target for traditional Chinese medicine in the treatment of cardiovascular diseases [PDF]
Frontiers in PharmacologyCardiovascular disease (CVD) is a serious public health problem, and among non-communicable diseases, CVD is now the leading cause of mortality and morbidity worldwide.
Jiahui Liu +6 more
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Journal of Inflammation, 2022 Background Pyroptosis was implicated in acute lung injury (ALI). Disulfiram is reported as an effective pyroptosis inhibitor by inhibiting gasdermin D(GSDMD).
Jiping Zhao +6 more
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