Results 11 to 20 of about 86,263 (270)

Blockade of high-mobility group box 1 attenuates intestinal mucosal barrier dysfunction in experimental acute pancreatitis

open access: yesScientific Reports, 2017
The release of inflammatory cytokines, that plays a dominant role in local pancreatic inflammation and systemic complications in severe acute pancreatitis (SAP).
Xia Chen   +3 more
doaj   +2 more sources

Maintenance of intestinal homeostasis by mucosal barriers [PDF]

open access: yesInflammation and Regeneration, 2018
Background The intestine is inhabited by a tremendous number of microorganisms, which provide many benefits to nutrition, metabolism and immunity. Mucosal barriers by intestinal epithelial cells make it possible to maintain the symbiotic relationship ...
Ryu Okumura, Kiyoshi Takeda
doaj   +3 more sources

The Effect of Peritoneal Air Exposure on Intestinal Mucosal Barrier [PDF]

open access: yesGastroenterology Research and Practice, 2014
Background. Damage of the intestinal mucosa barrier may result in intestinal bacterial and endotoxin translocation, leading to local and systemic inflammation. The present study was designed to investigate whether peritoneal air exposure induces damage of intestinal mucosal barrier.Methods.
Jun Bao   +11 more
openaire   +4 more sources

Intestinal Mucosal Barrier Is Injured by BMP2/4 via Activation of NF-κB Signals after Ischemic Reperfusion [PDF]

open access: yesMediators of Inflammation, 2014
Intestinal ischemic reperfusion (I/R) can cause dysfunction of the intestinal mucosal barrier; however, the mechanism of the intestinal mucosal barrier dysfunction caused by I/R remains unclear.
Kang Chen   +7 more
doaj   +2 more sources

Progress in Mycotoxins Affecting Intestinal Mucosal Barrier Function [PDF]

open access: yesInternational Journal of Molecular Sciences, 2019
Mycotoxins, which are widely found in feed ingredients and human food, can exert harmful effects on animals and pose a serious threat to human health. As the first barrier against external pollutants, the intestinal mucosa is protected by a mechanical barrier, chemical barrier, immune barrier, and biological barrier. Firstly, mycotoxins can disrupt the
Zhihua Ren   +6 more
openaire   +3 more sources

Intestinal Mucosal Barrier Is Regulated by Intestinal Tract Neuro-Immune Interplay [PDF]

open access: yesFrontiers in Pharmacology, 2021
Inflammatory bowel disease, irritable bowel syndrome and severe central nervous system injury can lead to intestinal mucosal barrier damage, which can cause endotoxin/enterobacteria translocation to induce infection and is closely related to the ...
Xin-yu You   +7 more
doaj   +3 more sources

Effects of different environmental intervention durations on the intestinal mucosal barrier and the brain-gut axis in rats with colorectal cancer

open access: yesScientific Reports, 2022
An enriched environment (EE) is a promising strategy for protecting the intestinal mucosal barrier and regulating the brain-gut axis, but the optimal EE intervention duration is unknown.
Liu Dun   +4 more
doaj   +2 more sources

From the intestinal mucosal barrier to the enteric neuromuscular compartment: an integrated overview on the morphological changes in Parkinson’s disease [PDF]

open access: yesEuropean Journal of Histochemistry, 2021
Gastrointestinal dysfunctions represent the most common non-motor symptoms in Parkinson’s disease (PD). Of note, changes in gut microbiota, impairments of intestinal epithelial barrier (IEB), bowel inflammation and neuroplastic rearrangements of the ...
Carolina Pellegrini   +6 more
doaj   +2 more sources

Intestinal epithelial barrier and mucosal immunity

open access: yesCellular and Molecular Life Sciences, 2005
Intestinal mucosa integrates primary digestive functions with immune functions such as pathogen surveillance, antigen transport and induction of mucosal immunity and tolerance. Intestinal adaptive immunity is elicited in organized mucosa-associated lymphoid tissue (O-MALT) that is composed of antigen-presenting cells and lymphocytes and achieved by ...
Rumbo, Martín, Schiffrin, Eduardo J.
  +12 more sources

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