Results 1 to 10 of about 134,087 (293)

Small nucleolar RNAs and SNHGs in the intestinal mucosal barrier: Emerging insights and current roles

open access: yesJournal of Advanced Research, 2023
Background: Previous studies have focused on the involvement of small nucleolar RNAs (snoRNAs) and SNHGs in tumor cell proliferation, apoptosis, invasion, and metastasis via multiple pathways, including phosphatidylinositol-3-kinase/protein kinase B ...
Tian Yang, Jun Shen
doaj   +4 more sources

Restoring mucosal barrier homeostasis by in situ formation of a living-synthetic therapeutic coating [PDF]

open access: yesNature Communications
The mucosal barrier consisting of physicochemical, immune, and microbial components is the first line of defense against external stimuli. Breakdown of the mucosal barrier causes the occurrences of various diseases, while methods capable of ...
Wei Yu   +9 more
doaj   +3 more sources

Mucosal Barrier Functions of Fish under Changing Environmental Conditions [PDF]

open access: yesFishes, 2019
The skin, gills, and gut are the most extensively studied mucosal organs in fish. These mucosal structures provide the intimate interface between the internal and external milieus and serve as the indispensable first line of defense.
Nikko Alvin R. Cabillon   +1 more
doaj   +4 more sources

Protective effect of zinc gluconate on intestinal mucosal barrier injury in antibiotics and LPS-induced mice

open access: yesFrontiers in Microbiology
ObjectiveThe aim of the study is to investigate the function and mechanism of Zinc Gluconate (ZG) on intestinal mucosal barrier damage in antibiotics and Lipopolysaccharide (LPS)-induced mice.MethodsWe established a composite mouse model by inducing ...
Yongcai Wang   +10 more
doaj   +4 more sources

The Role of Intestinal Mucosal Barrier in Autoimmune Disease: A Potential Target

open access: yesFrontiers in Immunology, 2022
Autoimmune diseases are a series of diseases involving multiple tissues and organs, characterized by the over production of abnormal multiple antibodies.
Jia An   +7 more
doaj   +3 more sources

Maintenance of intestinal homeostasis by mucosal barriers [PDF]

open access: yesInflammation and Regeneration, 2018
Background The intestine is inhabited by a tremendous number of microorganisms, which provide many benefits to nutrition, metabolism and immunity. Mucosal barriers by intestinal epithelial cells make it possible to maintain the symbiotic relationship ...
Ryu Okumura, Kiyoshi Takeda
doaj   +3 more sources

Repairing the intestinal mucosal barrier of traditional Chinese medicine for ulcerative colitis: a review

open access: yesFrontiers in Pharmacology, 2023
Damage to the intestinal mucosal barrier play an important role in the pathogenesis of ulcerative colitis (UC). Discovering the key regulators and repairing the disturbed barrier are crucial for preventing and treating UC.
Yichen Zong   +5 more
doaj   +3 more sources

Non-canonical IL‑22 receptor signaling remodels the oral mucosal barrier during Candida albicans immunosurveillance [PDF]

open access: yesNature Communications
Mucosal barrier integrity is vital for homeostasis with commensal organisms while preventing pathogen invasion. Here we show that fungal-induced immunosurveillance enhances resistance to fungal outgrowth and tissue invasion by remodeling the oral mucosal
Nicolas Millet   +14 more
doaj   +2 more sources

Laryngopharyngeal Reflux and Inflammatory Responses in Mucosal Barrier Dysfunction of the Upper Aerodigestive Tract

open access: yesJournal of Inflammation Research, 2021
Danling Liu,1,* Tingting Qian,1,* Shan Sun,1 Jack J Jiang1,2 1Otorhinolaryngology Department, ENT Institute, Eye & ENT Hospital, State Key Laboratory of Medical Neurobiology, NHC Key Laboratory of Hearing Medicine Research, Fudan University, Shanghai
Liu D, Qian T, Sun S, Jiang JJ
doaj   +2 more sources

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