Results 21 to 30 of about 134,087 (293)

Intestinal Barrier, Permeability and Nonspecific Inflammation in Functional Gastrointestinal Disorders

open access: yesРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии, 2020
Aim of review. Description of intestinal mucosal barrier permeability disruption causes as morbid factors in gastrointestinal tract (GIT) functional disorders.General provisions.
A. L. Kovaleva   +2 more
doaj   +1 more source

Perspectives on Mucosal Vaccines: Is Mucosal Tolerance a Barrier? [PDF]

open access: yesThe Journal of Immunology, 2007
Abstract Mucosal administration of Ags induces specific Abs in external secretions and systemic unresponsiveness termed oral or mucosal tolerance. The dominant response depends on the species studied, the nature, dose, frequency, route of Ag application, and the use of adjuvants.
Jiri, Mestecky   +2 more
openaire   +2 more sources

Maintenance of Barrier Tissue Integrity by Unconventional Lymphocytes

open access: yesFrontiers in Immunology, 2021
Mucosal surfaces, as a first barrier with the environment are especially susceptible to damage from both pathogens and physical trauma. Thus, these sites require tightly regulated repair programs to maintain barrier function in the face of such insults ...
Joshua R. Cox   +4 more
doaj   +1 more source

Biliary Mucosal Barrier and Microbiome [PDF]

open access: yesVisceral Medicine, 2015
<b><i>Background:</i></b> The biliary system is in continuous contact with the complex microbiota of the intestine. Microbial products have recently been proposed as potential triggers for biliary diseases. <b><i>Methods:</i></b> The aim of this review is to provide a summary of the current knowledge ...
Julien Verdier   +2 more
openaire   +2 more sources

Pathways involved in gut mucosal barrier dysfunction induced in adult rats by maternal deprivation: corticotrophin-releasing factor and nerve growth factor interplay [PDF]

open access: yes, 2007
Neonatal maternal deprivation (NMD) increases gut paracellular permeability (GPP) through mast cells and nerve growth factor (NGF), and modifies corticotrophin-releasing factor (CRF) and corticosterone levels.
Lionel Bueno   +17 more
core   +1 more source

Editorial : Overcoming challenges in mucosal immunity : 2022 [PDF]

open access: yes, 2023
The mucous-producing membranes house the highest concentration of lymphoid tissue in the vertebrate body due to their extensive interaction with the external environment.
Laceta, Javier   +2 more
core   +1 more source

Role of Barrier Integrity and Dysfunctions in Maintaining the Healthy Gut and Their Health Outcomes

open access: yesFrontiers in Physiology, 2021
Mucosal surface layers are the critical borders throughout epithelial membranes. These epithelial cells segregate luminal material from external environments.
Shruti Panwar   +2 more
doaj   +1 more source

Skin barrier immunology from early life to adulthood

open access: yes, 2023
Our skin has a unique barrier function, which is imperative for the body's protection against external pathogens and environmental insults. Although interacting closely and sharing many similarities with key mucosal barrier sites, such as the gut and the
Aurélien Trompette   +3 more
core   +1 more source

Gut Microbiome Homeostasis and the CD4 T- Follicular Helper Cell IgA Axis in Human Immunodeficiency Virus Infection

open access: yesFrontiers in Immunology, 2021
Human Immunodeficiency Virus (HIV) and Simian Immunodeficiency Virus (SIV) are associated with severe perturbations in the gut mucosal environment characterized by massive viral replication and depletion of CD4 T cells leading to dysbiosis, breakdown of ...
Olusegun O. Onabajo   +1 more
doaj   +1 more source

NOD-like receptors mediate homeostatic intestinal epithelial barrier function: promising therapeutic targets for inflammatory bowel disease

open access: yesTherapeutic Advances in Gastroenterology, 2023
Inflammatory bowel disease (IBD) is a chronic gastrointestinal inflammatory disease that involves host genetics, the microbiome, and inflammatory responses.
Feng Zhou   +5 more
doaj   +1 more source

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