Results 31 to 40 of about 127,813 (257)

Mucins in the mucosal barrier to infection [PDF]

Mucosal Immunology, 2008
The mucosal tissues of the gastrointestinal, respiratory, reproductive, and urinary tracts, and the surface of the eye present an enormous surface area to the exterior environment. All of these tissues are covered with resident microbial flora, which vary considerably in composition and complexity.
Linden, S. K., Sutton, P., Karlsson, N.G., Korolik, V., McGuckin, M. A.   +4 more
openaire   +5 more sources

Role of Barrier Integrity and Dysfunctions in Maintaining the Healthy Gut and Their Health Outcomes

Frontiers in Physiology, 2021
Mucosal surface layers are the critical borders throughout epithelial membranes. These epithelial cells segregate luminal material from external environments.
Shruti Panwar, Sapna Sharma, Prabhanshu Tripathi   +2 more
doaj   +1 more source

NOD-like receptors mediate homeostatic intestinal epithelial barrier function: promising therapeutic targets for inflammatory bowel disease

Therapeutic Advances in Gastroenterology, 2023
Inflammatory bowel disease (IBD) is a chronic gastrointestinal inflammatory disease that involves host genetics, the microbiome, and inflammatory responses.
Feng Zhou, Guo Dong Zhang, Yang Tan, Shi An Hu, Qun Tang, Gang Pei   +5 more
doaj   +1 more source

Gut Microbiome Homeostasis and the CD4 T- Follicular Helper Cell IgA Axis in Human Immunodeficiency Virus Infection

Frontiers in Immunology, 2021
Human Immunodeficiency Virus (HIV) and Simian Immunodeficiency Virus (SIV) are associated with severe perturbations in the gut mucosal environment characterized by massive viral replication and depletion of CD4 T cells leading to dysbiosis, breakdown of ...
Olusegun O. Onabajo, Joseph J. Mattapallil   +1 more
doaj   +1 more source

Modulation of Gut Barrier Functions in Ulcerative Colitis by Hyaluronic Acid System

Advanced Science, 2022
The active stages of intestinal inflammation and the pathogenesis of ulcerative colitis are associated with superficial mucosal damage and intermittent wounding that leads to epithelial barrier defects and increased permeability. The standard therapeutic
Niranjan G. Kotla, Isma Liza Mohd Isa, Swetha Rasala, Secil Demir, Rajbir Singh, Becca V. Baby, Samantha K. Swamy, Peter Dockery, Venkatakrishna R. Jala, Yury Rochev, Abhay Pandit   +10 more
doaj   +1 more source

Repairing the intestinal mucosal barrier of traditional Chinese medicine for ulcerative colitis: a review

Frontiers in Pharmacology, 2023
Damage to the intestinal mucosal barrier play an important role in the pathogenesis of ulcerative colitis (UC). Discovering the key regulators and repairing the disturbed barrier are crucial for preventing and treating UC.
Yichen Zong, Jie Meng, Tangyou Mao, Qiang Han, Peng Zhang, Lei Shi   +5 more
doaj   +1 more source

Simian Immunodeficiency Virus Infection of Rhesus Macaques Results in Delayed Zika Virus Clearance

mBio, 2019
Flaviviruses are controlled by adaptive immune responses but are exquisitely sensitive to interferon-stimulated genes (ISGs). How coinfections, particularly simian immunodeficiency viruses (SIVs), that induce robust ISG signatures influence flavivirus ...
Carol L. Vinton, Samuel J. Magaziner, Kimberly A. Dowd, Shelly J. Robertson, Emerito Amaro-Carambot, Erik P. Karmele, Alexandra M. Ortiz, Carly E. Starke, Joseph C. Mudd, Stephen S. Whitehead, Sonja M. Best, Theodore C. Pierson, Heather D. Hickman, Jason M. Brenchley   +13 more
doaj   +1 more source

Editorial: Allergen source-specific mucosal barrier disruptors [PDF]

Frontiers in Allergy
Rajna Minić, Lidija Burazer, Andrijana Nešić, Sabine Flicker   +3 more
doaj   +2 more sources

Contribution of Lactobacilli on Intestinal Mucosal Barrier and Diseases: Perspectives and Challenges of Lactobacillus casei

Life, 2022
The intestine barrier, the front line of normal body defense, relies on its structural integrity, microbial composition and barrier immunity. The intestinal mucosal surface is continuously exposed to a complex and dynamic community of microorganisms ...
Da Qin, Yixuan Ma, Yanhong Wang, Xilin Hou, Liyun Yu   +4 more
doaj   +1 more source

PEGylated bacteria restore intestinal mucosal barrier [PDF]

Acta Pharmaceutica Sinica B
Menghang Zu, Xue Xia, Bo Xiao
doaj   +2 more sources