Results 41 to 50 of about 134,087 (293)
, 2009 Background Microbial infections induce ileal pancreatitis-associated protein/regenerating gene III (PAP/RegIII) mRNA expression. Despite increasing interest, little is known about the PAP/RegIII protein.
van der Meer, R. +9 more
core +1 more source
PEGylated bacteria restore intestinal mucosal barrier [PDF]
Acta Pharmaceutica Sinica BMenghang Zu, Xue Xia, Bo Xiao
doaj +2 more sources
Barriers of Mucosal Entry of HIV/SIV [PDF]
Current Immunology Reviews, 2019 Most new HIV infections, over 80%, occur through sexual transmission. During sexual transmission, the virus must bypass specific female and male reproductive tract anatomical barriers to encounter viable target cells. Understanding the generally efficient ability of these barriers to exclude HIV and the precise mechanisms of HIV translocation beyond ...
Ann M, Carias, Thomas J, Hope
openaire +2 more sources
Potential Roles of Exosomal lncRNAs in the Intestinal Mucosal Immune Barrier
Journal of Immunology Research, 2021 The intestinal mucosal immune barrier protects the host from the invasion of foreign pathogenic microorganisms. Immune cells and cytokines in the intestinal mucosa maintain local and systemic homeostasis by participating in natural and adaptive immunity.
Shanshan Chen +4 more
doaj +1 more source
Effect of zinc on the intestinal barrier function of weaned piglets
Siliao yanjiu, 2021 Zinc has various physiological function, such as improving growth performance, reproductive performance, increasing antioxidant and immune capacity, increasing collagen, keratin and epithelial layer thickness, and plays an important role in regulating ...
Hui-yun WANG, Yang-kui XIANG, Shu-jun WU
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Th22 cells and the intestinal mucosal barrier
Frontiers in Immunology, 2023 T-helper 22 (Th22) cells represent a novel subset of CD4+ T cells that exhibit distinctive characteristics, namely the secretion of IL-22 while abstaining from secreting IL-17 and interferon-γ (IFN-γ). These cells serve as the primary source of IL-22, and both Th22 cells and IL-22 are believed to play a role in maintaining intestinal mucosal ...
Jieli Chen, Jun Yao
openaire +3 more sources
, 2018 Understanding the function of oral mucosal epithelial barriers is essential for a plethora of research fields such as tumor biology, inflammation and infection diseases, microbiomics, pharmacology, drug delivery, dental and biomarker research.
Gruber, Reinhard +3 more
core +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source