Results 21 to 30 of about 86,263 (270)
Th22 cells and the intestinal mucosal barrier. [PDF]
Front Immunol, 2023 T-helper 22 (Th22) cells represent a novel subset of CD4+ T cells that exhibit distinctive characteristics, namely the secretion of IL-22 while abstaining from secreting IL-17 and interferon-γ (IFN-γ). These cells serve as the primary source of IL-22, and both Th22 cells and IL-22 are believed to play a role in maintaining intestinal mucosal ...
Chen J, Yao J.
europepmc +4 more sources
Role of polyamines in intestinal mucosal barrier function. [PDF]
Semin ImmunopatholThe intestinal epithelium is a rapidly self-renewing tissue; the rapid turnover prevents the invasion of pathogens and harmful components from the intestinal lumen, preventing inflammation and infectious diseases. Intestinal epithelial barrier function depends on the epithelial cell proliferation and junctions, as well as the state of the immune system
Nakamura A, Matsumoto M.
europepmc +3 more sources
Mechanism of Qingchang Suppository on repairing the intestinal mucosal barrier in ulcerative colitis [PDF]
, 2023 Ulcerative colitis (UC) is a refractory inflammatory bowel disease, and the outcomes of conventional therapies of UC, including 5-aminosalicylic acid, glucocorticoids, immunosuppressants, and biological agents, are not satisfied with patients and ...
Jianye Yuan +4 more
core +1 more source
At the Forefront of the Mucosal Barrier: The Role of Macrophages in the Intestine [PDF]
Cells, 2020 Macrophages are part of the innate immunity and are key players for the maintenance of intestinal homeostasis. They belong to the group of mononuclear phagocytes, which exert bactericidal functions and help to clear apoptotic cells. Moreover, they play essential roles for the maintenance of epithelial integrity and tissue remodeling during wound ...
Ruder, Barbara, Becker, Christoph
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Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2020 Aim of review. Description of intestinal mucosal barrier permeability disruption causes as morbid factors in gastrointestinal tract (GIT) functional disorders.General provisions.
A. L. Kovaleva +2 more
doaj +1 more source
Therapeutic Advances in Gastroenterology, 2023 Inflammatory bowel disease (IBD) is a chronic gastrointestinal inflammatory disease that involves host genetics, the microbiome, and inflammatory responses.
Feng Zhou +5 more
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Potential Roles of Exosomal lncRNAs in the Intestinal Mucosal Immune Barrier
Journal of Immunology Research, 2021 The intestinal mucosal immune barrier protects the host from the invasion of foreign pathogenic microorganisms. Immune cells and cytokines in the intestinal mucosa maintain local and systemic homeostasis by participating in natural and adaptive immunity.
Shanshan Chen +4 more
doaj +1 more source
Canadian Journal of Infectious Diseases and Medical Microbiology, 2023 The intestinal microbiota is an “invisible organ” in the human body, with diverse components and complex interactions. Homeostasis of the intestinal microbiota plays a pivotal role in maintaining the normal physiological process and regulating immune ...
Zhaoyi Pan, Nanping Wu, Changzhong Jin
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Artificial Nutrition and Intestinal Mucosal Barrier Functionality [PDF]
Digestion, 2013 The gastrointestinal tract has a major role in digestion and absorption of nutrients while playing a leading role in defense of the body. It forms a shield against the invasion of various microorganisms or their products (e.g. antigens, toxins) and therefore it is important to establish its integrity and functionality.
Chrysostomos D, Anastasilakis +3 more
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The Role of lncRNAs in Regulating the Intestinal Mucosal Mechanical Barrier [PDF]
BioMed Research International, 2021 lncRNA is a transcript that is more than 200 bp in length. Currently, evidence has shown that lncRNA is of great significance in cell activity, involved in epigenetics, gene transcription, chromatin regulation, etc. The existence of an intestinal mucosal mechanical barrier hinders the invasion of pathogenic bacteria and toxins, maintaining the ...
Shanshan Chen +5 more
openaire +2 more sources