Results 1 to 10 of about 726,579 (340)

Deficiency of Splicing Factor 1 (SF1) Reduces Intestinal Polyp Incidence in Apc^Min/+ Mice [PDF]

Biology, 2020
Background: Splicing factor 1 (SF1) is a conserved alternative splicing factor expressed in many different mammalian cell types. The genetically modified Sf1+/− (or Sf1β-geo/+) mice express reduced levels of SF1 protein in mouse tissues, including in ...
Jyotsna D. Godavarthi, Shahrazad Polk, Lisa Nunez, Amruthesh Shivachar, Nancy L. Glenn Griesinger, Angabin Matin   +5 more
doaj   +3 more sources

Small Intestinal Polyp Burden in Pediatric Peutz–Jeghers Syndrome Assessed through Capsule Endoscopy: A Longitudinal Study [PDF]

Children, 2023
The management of pediatric Peutz–Jeghers Syndrome (PJS) focuses on the prevention of intussusception complicating small intestinal (SI) polyposis. This hinges on the accurate appraisal of the polyp burden to tailor therapeutic interventions.
Jeremy Stewart, Nathan R. Fleishman, Vincent S. Staggs, Mike Thomson, Nicole Stoecklein, Caitlin E. Lawson, Michael P. Washburn, Shahid Umar, Thomas M. Attard   +8 more
doaj   +4 more sources

HASPIN kinase inhibitor CHR-6494 suppresses intestinal polyp development, cachexia, and hypogonadism in Apcmin/+ mice. [PDF]

Eur J Cancer Prev, 2020
HASPIN has been identified as a nuclear Ser/Thr kinase specifically expressed in haploid germ cells. HASPIN kinase inhibitors were recently isolated, and their antitumor activity reported. Colorectal cancer occurs with high incidence worldwide.
Tanaka H, Wada M, Park J.
europepmc   +3 more sources

Promotion or Suppression of Murine Intestinal Polyp Development by iNKT Cell Directed Immunotherapy. [PDF]

Front Immunol, 2019
The glycosphingolipid α-galactosylceramide (α-GalCer) is a well-described immune activator with strong anti-tumor properties in animal models. It is presented on CD1d and acts by stimulating the invariant, type I, natural killer T (iNKT) lymphocytes to ...
Wang Y, Sedimbi SK, Löfbom L, Besra GS, Porcelli SA, Cardell SL.   +5 more
europepmc   +3 more sources

Multiplex immunohistochemistry reveals histological features of three different intestinal polyp subtypes in pediatric patients [PDF]

BMC Pediatrics
Background Histologically, our understanding of intestinal polyps remains limited in scope, particularly regarding the diverse subtypes observed in pediatric patients.
Lanlan Huang, Xinjia Liu, Songyang Li, Yongjie Liu, Weijian Chen, Yana Li, Hongyan Peng, Xiangyu Wang, Peiwen Xiong, Qinglan Yang, Shuting Wu, Ling Che, Hongmei Zhao, Yafei Deng   +13 more
doaj   +3 more sources

Factors Affecting Adenoma Risk Level in Patients with Intestinal Polyp and Association Analysis. [PDF]

J Healthc Eng, 2022
Objective To explore the factors affecting the adenoma risk level in patients with intestinal polyp and association. Methods The clinical data of 3,911 patients with intestinal polyp treated in our hospital from January 2018 to January 2021 were ...
Dai Y, Chen W, Xu X, Chen J, Mo W, Chen Y, Xu S.   +6 more
europepmc   +2 more sources

Intestinal schistosomiasis masquerading as intestinal polyps [PDF]

BMC Infectious Diseases, 2021
Abstract Background Schistosomiasis is very common in the southern part of the Yangtze River Basin in China. It is mainly manifested as appendicitis, ulcers, hematomas, and thickening of the intestinal tract. Schistosomiasis of the appendix is rare, mainly manifested as appendicitis, which is easy to be misdiagnosed.
Xiu Li Zhu, Ji Zhong Song, Wen Yong Yu, Li Qun Hua, Ming Li Zhang   +4 more
openaire   +5 more sources

Theracurmin inhibits intestinal polyp development in Apc-mutant mice by inhibiting inflammation-related factors. [PDF]

Cancer Sci, 2020
Colorectal cancer (CRC) is the second leading cause of cancer death worldwide. Therefore, it is important to establish useful methods for preventing CRC.
Adachi S, Hamoya T, Fujii G, Narita T, Komiya M, Miyamoto S, Kurokawa Y, Takahashi M, Takayama T, Ishikawa H, Tashiro K, Mutoh M.   +11 more
europepmc   +2 more sources

Genetic mapping of novel modifiers for Apc Min induced intestinal polyps’ development using the genetic architecture power of the collaborative cross mice [PDF]

BMC Genomics, 2021
Background Familial adenomatous polyposis is an inherited genetic disease, characterized by colorectal polyps. It is caused by inactivating mutations in the Adenomatous polyposis coli (Apc) gene. Mice carrying a nonsense mutation in the Apc gene at R850,
Alexandra Dorman, Ilona Binenbaum, Hanifa J. Abu-Toamih Atamni, Aristotelis Chatziioannou, Ian Tomlinson, Richard Mott, Fuad A. Iraqi   +6 more
doaj   +2 more sources

Factors Associated with Intestinal Polyp Recurrence after Electroresection

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2023
OBJECTIVE To investigate the frequency of recurrence after colonoscopic high-frequency electroresection of intestinal polyps and analyse the risk factors associated with recurrence. STUDY DESIGN Observational study.
Juan Jin, Bo Yan, Shanfeng Yang, Min Du
openalex   +3 more sources